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Haibe-Kains, Benjamin; El-Hachem, Nehme; Birkbak, Nicolai Juul; Jin, Andrew C; Beck, Andrew H; Aerts, Hugo J W L; Quackenbush, John
Nature (London), 12/2013, Letnik: 504, Številka: 7480Journal Article
Two large-scale pharmacogenomic studies were published recently in this journal. Genomic data are well correlated between studies; however, the measured drug response data are highly discordant. Although the source of inconsistencies remains uncertain, it has potential implications for using these outcome measures to assess gene-drug associations or select potential anticancer drugs on the basis of their reported results.
