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Mulkey, Sarah B., MD, PhD; Ramakrishnaiah, Raghu H., MBBS; McKinstry, Robert C., MD, PhD; Chang, Taeun, MD; Mathur, Amit M., MD; Mayock, Dennis E., MD; Van Meurs, Krisa P., MD; Schaefer, G. Bradley, MD; Luo, Chunqiao, MS; Bai, Shasha, PhD; Juul, Sandra E., MD, PhD; Wu, Yvonne W., MD, MPH
The Journal of pediatrics, 07/2017, Letnik: 186Journal Article
In the Neonatal Erythropoietin and Therapeutic Hypothermia Outcomes study, 9/20 erythropoietin-treated vs 12/24 placebo-treated infants with hypoxic-ischemic encephalopathy had acute brain injury. Among infants with acute brain injury, the injury volume was lower in the erythropoietin than the placebo group ( P = .004). Higher injury volume correlated with lower 12-month neurodevelopmental scores. Trial registration ClinicalTrials.gov : NCT01913340.
