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  • Clinical translation of a h...
    Gilja, Vikash; Pandarinath, Chethan; Blabe, Christine H; Nuyujukian, Paul; Simeral, John D; Sarma, Anish A; Sorice, Brittany L; Perge, János A; Jarosiewicz, Beata; Hochberg, Leigh R; Shenoy, Krishna V; Henderson, Jaimie M

    Nature medicine, 10/2015, Letnik: 21, Številka: 10
    Journal Article

    Neural prostheses have the potential to improve the quality of life of individuals with paralysis by directly mapping neural activity to limb- and computer-control signals. We translated a neural prosthetic system previously developed in animal model studies for use by two individuals with amyotrophic lateral sclerosis who had intracortical microelectrode arrays placed in motor cortex. Measured more than 1 year after implant, the neural cursor-control system showed the highest published performance achieved by a person to date, more than double that of previous pilot clinical trial participants.