ABSTRACT People with disabilities is one of the most vulnerable groups in any society. The objective of this paper is to reflect about the inclusion and exclusion of people with disabilities in Mexico and specifically in the state of Guanajuato, which helps to understand what happens with government initiatives to provide assistance and support to this sector, population, which is still far from fully exercising its right to work and an independent life. The conclusions suggest that societies are increasingly aware of diversity, however, exclusion still prevails for people with disabilities in different spheres, especially labor, which is reinforced by stereotypes that limit the exercise of their human rights. La disminución o carencia de alguna capacidad física o mental deriva en desigualdad, exclusión, rezago social y pobreza, lo cual dificulta la integración de este sector de la población al mercado laboral, de modo que se considera población vulnerable.