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  • Dopaminergic modulation of ...
    Cobacho, Nuria; de la Calle, José Luis; Paíno, Carlos Luis

    Brain research bulletin, 07/2014, Letnik: 106
    Journal Article

    Highlights • Quinpirole alleviates cold and tactile allodynia in a rat model of neuropathic pain. • Spinal mechanisms might be involved in the anti-allodynic effect of quinpirole. • However, supraspinal mechanisms probably account for most of the analgesic activity. • Pain relief is gradually achieved when quinpirole in chronically administered. • The study shows the potential of D2R agonists for the management of neuropathic pain.