ObjectiveTo assess the burden of urological symptoms in a clinically defined cohort of patients with a clinical diagnosis of PSP and CBS.BackgroundUrinary symptoms are common in PD and atypical parkinsonian syndromes. Urological dysfunction significantly impacts quality of life and may portend a worse prognosis. However, studies addressing this in PSP and CBS remain relatively few in number.MethodsA retrospective review of patients attending two atypical parkinsonism clinics in Dublinwith a diagnosis of PSP was performed. The prevalence of irritative and obstructive urological symptoms in the cohort was assessed. The range of therapeutic interventions deployed were reviewed.Results30 patients (14 female, 16 male, 20 PSP, 10 CBS) were included in the study. Urological symptoms were reported in 66.6% of patients. The most commonly reported symptom was nocturia (n=11, 37%). Irritative symptoms predominated (n=17, 57%) over obstructive symptoms (n=4, 13%). Mirabegron was the most commonly used medication (n=4, 13%). 2 patients required long term catheters.ConclusionsUrological symptoms are common in tauopathies and our experience reflects the high prevalence found in some previous studies. Developing effective strategies for investigating and treating urological dysfunction in PSP and CBS has the potential to improve quality of life for patients.