The article discusses the main parameters of interaction between industrial sites and settlement areas in the Ural plant towns. Fundamental transformations of the old industrial areas in the 20th century based on the new modernist principles have disrupted the historically established architectural and urban planning structure of workers' settlements. Today, the fragmentation and disorganization of the urban space is a significant problem that impedes the sustainable socio-economic and cultural development of plant towns. The parameters that determine the nature of interaction between plant and urban space make it possible to assess a certain Ural old industrial town in relation to problems and potential for reintegration of its industrial production site into the structure of the settlement.