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Lin, Y.-J.; Chang, W.-N.; Chang, H.-W.; Ho, J.-T.; Lee, T.-C.; Wang, H.-C.; Tsai, N.-W.; Tsai, M.-H.; Lu, C.-H.
European journal of neurology, 20/May , Letnik: 15, Številka: 5Journal Article
Background and purpose: Seizures are important neurologic complications of spontaneous aneurysmal subarachnoid hemorrhage (SAH). A better understanding of the risk factors of seizures following aneurysmal SAH is needed to predict those who will require treatment. Methods: A total of 137 adult patients were enrolled in this two‐year retrospective study. Baseline prognostic variables were analyzed based on Cox’s proportional hazards model after a minimum of one‐year follow‐up. Results: Seizures occurred in 21 patients who had SAH, including acute symptomatic seizures in 11.7% (16/137) and unprovoked seizures in 3.6% (5/137). None progressed to status epilepticus during hospitalization. After a minimum of one‐year follow‐up, the mean Glasgow Outcome Score was 3.5 ± 1.4 for patients with seizures and 3.1 ± 1.1 for those without. Conclusions: Higher mean World Federation of Neurological Societies grade on presentation was predictive of seizure, but seizure itself was not a significant prognostic predictor after a minimum of one‐year follow‐up. Regarding potential side effects of anti‐epileptic drugs, anti‐epileptic therapy should be carefully administered to patients with seizures after aneurysmal SAH.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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in: SICRIS
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