The article presents the results of determining the dynamic loading of a tank wagon with malleable links between the pot and the frame. This solution will help to reduce the loading of the load-bearing structure of a tank wagon in the vertical plane. Mathematical modelling of the dynamic loading of the load-bearing structure of a tank wagon was carried out. As a prototype, the tank wagon of model 15-1443-06 was selected, with the actual dimensions of structural components recorded during field studies. It was established that the accelerations acting on the pot of the tank wagon were about 2.6 m/s2. The fields of distribution of accelerations relative to the load-bearing structure of the tank wagon were determined. The discrepancy between the results of computer and mathematical modelling was about 8%. The coefficient of fatigue strength reserve of the load-bearing structure of the tank wagon was calculated. The results of the calculation showed that the coefficient of fatigue resistance is 15% higher than permissible. The conducted research will help to reduce the loading of the load-bearing structures of tank wagons during operational modes, extend the life and safety of their operation, reduce maintenance costs, as well as create recommendations for the design of innovative structures.