•New decentralized multi-scale controller design for MIMO processes.•Multi-scale control (MSC) scheme leads to PID controller with augmented filter.•Effective approach to synthesize PID controllers for MIMO processes.•Numerical examples demonstrate the usefulness of the proposed approach. Based on the recently proposed (SISO) multi-scale control scheme, a new approach is introduced to design multi-loop controllers for multivariable processes. The basic feature of the multi-scale control scheme is to decompose a given plant into a sum of basic modes. To achieve good nominal control performance and performance robustness, a set of sub-controllers are designed based on the plant modes in such a way that they are mutually enhanced with each other so as to optimize the overall control objective. It is shown that the designed multi-scale controller is equivalent to a conventional PID controller augmented with a filter. The multi-scale control scheme offers a systematic approach to designing multi-loop PID controllers augmented with filters. Numerical studies show that the proposed multi-loop multi-scale controllers provide improved nominal performance and performance robustness over some well-established multi-loop PID controller schemes.