Course-based undergraduate research experiences (CUREs) have been increasingly incorporated into science, technology, engineering, and mathematics (STEM) curricula, leading to greater inclusion of students in real-world STEM practices. Implicit within the definition of CUREs is the notion that generated research findings will have relevancy to one or more communities beyond the boundaries of the classroom. However, limited studies have examined this dimension of CUREs, and those that have present conflicting results. To address these concerns, we conducted an exploratory mixed methods study to investigate the impact of embedding a museum education experience into a one-semester introductory biology CURE on student, faculty, and staff outcomes. Analysis of student survey data indicated improvement in attitudes, confidence, and science/museum skills following participation in the CURE. Semi-structured interview responses provided by CURE faculty and museum staff revealed similar perceptions, highlighting the value of museums as a novel avenue for engaging CURE students. Collectively, these data suggest that involving and supporting STEM students in the design and installation of museum exhibits has the potential to be a powerful tool for achieving broader relevance in CUREs.