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Marchesi, Federico; Valente, Marina; Riccò, Matteo; Rottoli, Matteo; Baldini, Edoardo; Mecheri, Fouzia; Bonilauri, Stefano; Boschi, Sergio; Bernante, Paolo; Sciannamea, Andrea; Rolla, Jessica; Francescato, Alice; Bollino, Ruggero; Cartelli, Concetto; Lanaia, Andrea; Anzolin, Francesca; Del Rio, Paolo; Fabbi, Diletta; Petracca, Gabriele Luciano; Tartamella, Francesco; Dalmonte, Giorgio
Obesity surgery, 06/2021, Letnik: 31, Številka: 6Journal Article
Introduction The favorable effects of bariatric surgery (BS) on overall pulmonary function and obesity-related comorbidities could influence SARS-CoV-2 clinical expression. This has been investigated comparing COVID-19 incidence and clinical course between a cohort of patients submitted to BS and a cohort of candidates for BS during the spring outbreak in Italy. Materials and Methods From April to August 2020, 594 patients from 6 major bariatric centers in Emilia-Romagna were administered an 87-item telephonic questionnaire. Demographics, COVID-19 incidence, suggestive symptoms, and clinical outcome parameters of operated patients and candidates to BS were compared. The incidence of symptomatic COVID-19 was assessed including the clinical definition of probable case, according to World Health Organization criteria. Results Three hundred fifty-three operated patients (Op) and 169 candidates for BS (C) were finally included in the statistical analysis. While COVID-19 incidence confirmed by laboratory tests was similar in the two groups (5.7% vs 5.9%), lower incidence of most of COVID-19-related symptoms, such as anosmia ( p: 0.046 ), dysgeusia ( p: 0.049 ), fever with rapid onset ( p: 0.046 ) were recorded among Op patients, resulting in a lower rate of probable cases (14.4% vs 23.7%; p: 0.009 ). Hospitalization was more frequent in C patients (2.4% vs 0.3%, p: 0.02). One death in each group was reported (0.3% vs 0.6%). Previous pneumonia and malignancies resulted to be associated with symptomatic COVID-19 at univariate and multivariate analysis. Conclusion Patients submitted to BS seem to develop less severe SARS-CoV-2 infection than subjects suffering from obesity.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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in: SICRIS
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