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Katz, Yarden; Wang, Eric T; Silterra, Jacob; Schwartz, Schraga; Wong, Bang; Thorvaldsdóttir, Helga; Robinson, James T; Mesirov, Jill P; Airoldi, Edoardo M; Burge, Christopher B
Bioinformatics, 07/2015, Letnik: 31, Številka: 14Journal Article
Analysis of RNA sequencing (RNA-Seq) data revealed that the vast majority of human genes express multiple mRNA isoforms, produced by alternative pre-mRNA splicing and other mechanisms, and that most alternative isoforms vary in expression between human tissues. As RNA-Seq datasets grow in size, it remains challenging to visualize isoform expression across multiple samples. To help address this problem, we present Sashimi plots, a quantitative visualization of aligned RNA-Seq reads that enables quantitative comparison of exon usage across samples or experimental conditions. Sashimi plots can be made using the Broad Integrated Genome Viewer or with a stand-alone command line program. Software code and documentation freely available here: http://miso.readthedocs.org/en/fastmiso/sashimi.html
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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