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Martin, Tim; Houck, Jon M.; Bish, Joel Pearson; Kičić, Dubravko; Woodruff, C. Chad; Moses, Sandra N.; Lee, Dustin C.; Tesche, Claudia D.
Human brain mapping, July 2006, Letnik: 27, Številka: 7Journal Article
Magnetoencephalography (MEG) was used to measure brain activity while participants performed a simple reaction to targets after either a random interval (uncued targets) or a series of isochronous warning stimuli with 200‐ms intervals that acted as a countdown. Targets could arrive “on time” or “early” relative to the preceding warning stimuli. Cerebellar activity before any stimulus onset predicted uncued simple reaction time. Onset of activity in somatomotor cortex relative to the target predicted reaction time after two warning stimuli when the target arrived on time or early. After three warning stimuli, when the target arrived on time and was certain to occur, prestimulus cerebellar activity and somatomotor onset were significant predictors of reaction time. When the target arrived early after three warning stimuli, prestimulus cerebellar and cingulate activity were predictive. The cerebellar results may reflect a number of possible factors, including a role in timing, response readiness, prediction and attention. Hum. Brain Mapping 2005. © 2005 Wiley‐Liss, Inc.
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