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  • Reductions in claudin-1 may...
    De Benedetto, Anna, MD; Slifka, Mark K., PhD; Rafaels, Nicholas M., MS; Kuo, I-Hsin, MS; Georas, Steve N., MD; Boguniewicz, Mark, MD; Hata, Tissa, MD; Schneider, Lynda C., MD; Hanifin, Jon M., MD; Gallo, Richard L., MD; Johnson, David C., PhD; Barnes, Kathleen C., PhD; Leung, Donald Y.M., MD, PhD; Beck, Lisa A., MD

    Journal of allergy and clinical immunology, 07/2011, Letnik: 128, Številka: 1
    Journal Article

    To the Editor: Atopic dermatitis (AD) is the most common inflammatory skin disease, affecting up to 20% of children in the United States, and is characterized by an increased susceptibility to cutaneous infections.1,2 One in 10 subjects with AD has difficulty clearing cutaneous infections with a host of viruses including herpes simplex, vaccinia, human papilloma, and/or molluscum contagiosum.1 This typically manifests as more extensive cutaneous and sometimes systemic disease and/or resistance to standard therapies.