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Declercq, Pierre-Louis; Fournel, Isabelle; Demeyere, Matthieu; Berraies, Anissa; Ksiazek, Eléa; Nyunga, Martine; Daubin, Cédric; Ampere, Alexandre; Sauneuf, Bertrand; Badie, Julio; Delbove, Agathe; Nseir, Saad; Artaud-Macari, Elise; Bironneau, Vanessa; Ramakers, Michel; Maizel, Julien; Miailhe, Arnaud-Felix; Lacombe, Béatrice; Delberghe, Nicolas; Oulehri, Walid; Georges, Hugues; Tchenio, Xavier; Clarot, Caroline; Redureau, Elise; Bourdin, Gaël; Federici, Laura; Adda, Mélanie; Schnell, David; Bousta, Mehdi; Salmon-Gandonnière, Charlotte; Vanderlinden, Thierry; Plantefeve, Gaëtan; Delacour, David; Delpierre, Cyrille; Le Bouar, Gurvan; Sedillot, Nicholas; Beduneau, Gaëtan; Rivière, Antoine; Meunier-Beillard, Nicolas; Gélinotte, Stéphanie; Rigaud, Jean-Philippe; Labruyère, Marie; Georges, Marjolaine; Binquet, Christine; Quenot, Jean-Pierre
Intensive care medicine, 08/2023, Letnik: 49, Številka: 10Journal Article
Purpose: Survivors after acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) are at high risk of developing respiratory sequelae and functional impairment. The healthcare crisis caused by the pandemic hit socially disadvantaged populations. We aimed to evaluate the influence of socio-economic status on respiratory sequelae after COVID-19 ARDS.Methods: We carried out a prospective multicenter study in 30 French intensive care units (ICUs), where ARDS survivors were pre-enrolled if they fulfilled the Berlin ARDS criteria. For patients receiving high flow oxygen therapy, a flow ≥ 50 l/min and an FiO2 ≥ 50% were required for enrollment. Socio-economic deprivation was defined by an EPICES (Evaluation de la Précarité et des Inégalités de santé dans les Centres d'Examens de Santé - Evaluation of Deprivation and Inequalities in Health Examination Centres) score ≥ 30.17 and patients were included if they performed the 6-month evaluation. The primary outcome was respiratory sequelae 6 months after ICU discharge, defined by at least one of the following criteria: forced vital capacity < 80% of theoretical value, diffusing capacity of the lung for carbon monoxide < 80% of theoretical value, oxygen desaturation during a 6-min walk test and fibrotic-like findings on chest computed tomography.Results: Among 401 analyzable patients, 160 (40%) were socio-economically deprived and 241 (60%) non-deprived; 319 (80%) patients had respiratory sequelae 6 months after ICU discharge (81% vs 78%, deprived vs non-deprived, respectively). No significant effect of socio-economic status was identified on lung sequelae (odds ratio (OR), 1.19 95% confidence interval (CI), 0.72-1.97), even after adjustment for age, sex, most invasive respiratory support, obesity, most severe P/F ratio (adjusted OR, 1.02 95% CI 0.57-1.83).Conclusions: In COVID-19 ARDS survivors, socio-economic status had no significant influence on respiratory sequelae 6 months after ICU discharge.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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in: SICRIS
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