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  • COVID-19 in Pregnancy and O...
    Mark, Elyse G.; McAleese, Samuel; Golden, W. Christopher; Gilmore, Maureen M.; Sick-Samuels, Anna; Curless, Melanie S.; Nogee, Lawrence M.; Milstone, Aaron M.; Johnson, Julia

    The Pediatric infectious disease journal, 05/2021, Letnik: 40, Številka: 5
    Journal Article

    Limited data are available about the outcomes of COVID-19 during pregnancy and risk of vertical transmission in exposed neonates. We reviewed studies published February 1, 2020, through August 15, 2020, on outcomes in pregnant women with COVID-19 and neonates with perinatal exposure. Among pregnant women with COVID-19, 181 (11%) required ICU admission and 123 (8%) required mechanical ventilation. There were 22 maternal deaths. Most infections occurred in the third trimester. Among women who delivered, 28% had a preterm birth and 57% had a Caesarean section. Sixty-one (4%) of 1222 neonates with reported testing had at least one positive SARS-CoV-2 polymerase chain reaction (PCR) test. The most common symptom among neonates was respiratory distress (n=126, 21%). There were 14 neonatal deaths, one of which occurred in a neonate with positive testing. Further study of COVID-19 in pregnant women and neonates, including standardized reporting of outcomes, testing, and treatment protocols, are essential to optimize maternal and neonatal care.