This paper expounds the emergency disposal technology based on mapping knowledge domain, dynamically integrates the mapping knowledge domain and emergency disposal plan, and uses data fusion technology to integrate multi-source heterogeneous data to construct the mapping knowledge domain of fire and coupling disasters, disaster management graph and supervision department graph. The mapping knowledge domain technology is used to establish a multi-department emergency response plan generation model with dynamic injection of data and process, realizes the cross-department and multi-agent efficient dynamic collaborative emergency response method, and provides data basis and auxiliary decision support for the generation of emergency plans.