Most of the patients with gastric cancer in China have been at the middle and advanced stages during diagnostic and treatment with poor prognosis overall. Perioperative radiotherapy, chemotherapy, immune therapy and other comprehensive treatment methods for gastric cancer patients preoperative and intraoperation may reduce tumor staging, increase the rate of surgical resection and prolong the time of patient survival. Perioperative comprehensive treatment has developed more than 30 years in China. Many results from relevant research were gotten combined with laying down the consensus and guidelines, and applied to clinic in recent years. With the emergence and development of new technologies and new strategies for comprehensive treatment, perioperative comprehensive treatment and conversion therapy will improve at much extent the rate of survival for gastric cancer patients in China.