Romania has aligned itself with objectives related to the conservation and protection of biodiversity, the safeguarding of natural habitats, and the protection of wild species by identifying and assessing Natura 2000 sites. These are recognized and protected not only at the European level but also internationally. They can be connected to broader ecological networks, such as the PanEuropean Ecological Corridors and international biodiversity protection networks, playing a significant role in promoting sustainable development by integrating nature conservation with socioeconomic activities. Additionally, they provide opportunities for biodiversity conservation, sustainable resource utilization, tourism development, and involvement of local communities. The study aims to identify the main forms of tourism practiced, as well as those with potential within the 15 Natura 2000 sites in the North-East region of Romania. In a comparative manner, it highlights best practices and measures necessary for promoting ecotourism and other sustainable economic activities that support nature conservation.