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Acute effects of coffeine on central and peripheral hemodynamics [Elektronski vir] = Akutni učinki kofeina na centralno in periferno hemodinamikoRajšp, Patric ; Križmarić, MiljenkoUvod Učinek kofeina na hemodinaiko še vedno skriva neznanke. V študiji smo raziskali učinek kofeina na variabilnost frekvence srca in na funkcijo srca. Metode Izvedli smo prospektivno dvojno slepo ... randomizirano študijo, ki je vključila 5 preiskovancev. Opazovali smo enkratni iztis srca (SV), minutni iztis srca (CO), krvni tlak (BP) in sistemsko upornost ožilja (TPR). Uporabili smo CNAP tehnologijo neprekinjenega merjenja krvnega tlaka. Rezultati Na dan pitja kave, smo zasledili povišanje tako sistoličnega (SBP) kot diastoličnega krvnega tlaka (DBP) (p<0,001). SBP je povišal za 35 %, DBP pa za 50 %. TPR se je povišala za 56 % (p<0,001). Klinično ni bilo sprememb med enkratnim iztisom srca in frekvenco srca zaradi zaužitja kofeina. Učinka nismo opazili v placebo obravnavi. Diskusija in zaključek Študija je pokazala, da so vzroki za povišanje krvnega tlaka v vazokonstrikciji. Prav tako lahko zaključimo, da je učinek kofeina med mirovanjem povezan s povečano aktivnostjo parasimpatičnega živčevja in zmanjšanega delovanja simpatičnega.Source: Zbornik predavanj [Elektronski vir] = Conference proceedings (Str. 258-260)Type of material - conference contributionPublish date - 2016Language - slovenianCOBISS.SI-ID - 2217124
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Rajšp, Patric | ![]() |
Križmarić, Miljenko | 25641 |
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