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Kontrola kvalitete DNA mikromrež nizke gostote = Quality control of low-density DNA microarraysDevjak, Rok ...DNA microarray technology, showing great perspective in clinical diagnostics and prognostics, is facing a problem of loosely defined and non-unified data quality control. We have developed a general ... approach for controlling the quality of low density DNA microarrays, which is based on the analysis of covariance of control probes. We have applied the approach to the Steroltalk microarray, which was developed to study genes in connection with cholesterol homeostasis. We analyzed changes in genes expression in human primary hepatocytes treated with rifampicin and rosuvastatin and evaluated the approach by comparing our results to these from the literature. The proposed approach is independent of the type of DNA microarray and therefore may contribute to more rapid transfer of this technology to the clinical practice.Source: Informatica medica slovenica. - ISSN 1318-2129 (Letn. 12, št. 2, 2007, str. 1-13)Type of material - article, component partPublish date - 2007Language - slovenianCOBISS.SI-ID - 23707353
Author
Devjak, Rok |
Režen, Tadeja |
Rozman, Damjana, 1960- |
Juvan, Peter, računalničar
Topics
Oligonucleotide Probes |
Gene Expression |
Cells, Cultured |
Drug Effects |
Liver |
Rifampin |
Antilipemic Agents |
Celične kulture |
Gensko izražanje |
Jetra |
Oligonukleotidne sonde |
Rifampin |
Lipolitiki
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Year | Impact factor | Edition | Category | Classification | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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DRS, in which the journal is indexed
Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Devjak, Rok | 30828 |
Režen, Tadeja | 22459 |
Rozman, Damjana, 1960- | 06013 |
Juvan, Peter, računalničar | 21352 |
Source: Personal bibliographies
and: SICRIS
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