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Stranski učinki bioloških zdravil pri vnetnih revmatičnih boleznih = Side effects of biological therapy used in inflammatory rheumatic diseasesGradišnik, Suzana, 1966- ...Uvedba zaviralcev dejavnika tumorske nekroze (TNF) alfa predstavlja pomemben napredek obravnave bolnikov z revmatoidnim artritisom. Poročila o primerih tuberkuloze, drugih resnih okužbah, kongestivni ... srčni odpovedi, malignomih in avtoimunih obolenjih podajajo sum o varnosti njihove uporabe. Pri vseh treh uporabljanih zaviralcih TNF alfa je povečano tveganje reaktivacije tuberkuloze. Po podatkih iz literature je povečano tveganje obolevanja za limfomi ne-Hodgkinovega tipa, ki je podobno tveganju pri bolnikih za RA, ki se zdravijo z drugimi zdravili. Ni podatkov o povečanem tveganju za nastanek solidnih tumorjev. Zaenkrat tudi ni dokazanega vpliva na izid nosečnosti ali teratogenem učinku.Source: Zbornik predavanj in praktikum (Str. 65-75)Type of material - conference contribution ; adult, seriousPublish date - 2007Language - slovenianCOBISS.SI-ID - 2671167
Author
Gradišnik, Suzana, 1966- |
Holc, Iztok, 1963- |
Dai, Klara |
Pahor, Artur
Topics
Arthritis, Rheumatoid |
therapy |
Revmatoidni artritis |
Zdravljenje |
Drug Therapy |
adverse effects |
Zdravljenje z zdravili |
Stranski učinki |
Tumor Necrosis Factor-alpha |
antagonists and inhibitors |
Tumor nekrotizirajoči faktor-alfa |
Antagonisti in inhibitorji
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Gradišnik, Suzana, 1966- | |
Holc, Iztok, 1963- | 23194 |
Dai, Klara | |
Pahor, Artur | 15750 |
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