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Gliomi nizkega gradusa pri otrocih in zdravljenje z inhibitorji MEK : prikaz primera = Pediatric low-grade gliomas and MEK ingibitors : case reportJenko, Urša, zdravnica ...Gliomi nizkega gradusa (angl. low-grade gliomas, LGG) so najpogostejši primarni tumorji v osrednjem živčnem sistemu pri otrocih. Histološko so heterogena skupina možganskih tumorjev. Najpogostejši ... med njimi je pilocitni astrocitom. V njihovo patogenezo je med drugim vpletena signalna pot proteinske kinaze, aktivirane z mitogenom (angl. mitogen-activated protein kinase, MAPK), zato je iskanje učinkovitih tarčnih zdravil z malo neželenimi učinki osrednji predmet trenutnih raziskav. V prispevku predstavljamo klinični primer dečka z neoperabilnim LGG, ki je bil slabo odziven na uveljavljene sistemske oblike zdravljenja, zato smo se odločili za tarčno zdravljenje z inhibitorjem MEK.Source: Slovenska pediatrija : revija Združenja pediatrov Slovenije in Združenja specialistov šolske in visokošolske medicine Slovenije. - ISSN 1318-4423 (Letn. 30, št. 3, 2023, str. 131-136)Type of material - article, component partPublish date - 2023Language - slovenianCOBISS.SI-ID - 173695747
source: Slovenska pediatrija : revija Združenja pediatrov Slovenije in Združenja specialistov šolske in visokošolske medicine Slovenije. - ISSN 1318-4423 (Letn. 30, št. 3, 2023, str. 131-136)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Jenko, Urša, zdravnica | |
Stefanović, Milica, 1983- | 34912 |
Faganel Kotnik, Barbara | 35916 |
Kitanovski, Lidija | 19257 |
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