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  • Defined picogram dose inclusion and release of macromolecules using polyelectrolyte microcapsules
    Dejugnat, Christophe ; Haložan, David ; Sukhorukov, Gleb B.
    Reversible pH=induced swelling of (PAH/PSS) polyelectrolyte microcapsules is accompanied by increase porosity, making them permeable to poly(acrylic acid)(PAA) at pH values higher than 11.2. This ... pH-switchable permeability was used to encapsulate the polyanion in alkaline conditions. Relationship between starting PAA concentration in solution and amount finally being encapsulated has been established and can be used further as calibration curve. A desired amount of encapsulate polymer in the picogram range per capsule can be achieved. The loaded capsules were then used as microreactors by forming a complex between the PAA and Ca2+ions.
    Source: Macromolecular rapid communications. - ISSN 1022-1336 (26, 12, Jun. 2005, str. 961-967)
    Type of material - article, component part ; adult, serious
    Publish date - 2005
    Language - english
    COBISS.SI-ID - 14187016

source: Macromolecular rapid communications. - ISSN 1022-1336 (26, 12, Jun. 2005, str. 961-967)

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