In this work, in a first step, a novel methacrylate monomer, 2-(4-hydroxyanilino)-2-oxoethyl-2-methylprop-2-enoate (HAOEME), was synthesized containing a phenolic hydroxyl group in the side branch. ...Then, the copolymers of this monomer were obtained by a free radical solution polymerization method with glycidyl methacrylate (GMA), a commercial monomer, at 65 °C in 1,4-dioxane solvent. The structural characterization of the synthesized monomers and copolymers was carried out using Fourier transform infrared (FTIR) spectroscopy, proton nuclear magnetic resonance (
1
H NMR), and
13
C NMR techniques. Based on the monomer reactivity ratios obtained, the HAOEME monomer was found to be more reactive than GMA. The thermogravimetric analysis results showed that the thermal resistance of copolymers increased with an increase in the number of HAOEME units in the copolymer. It was also observed that the Tg value of copolymers increased with an increase of the molar fraction of HAOEMA units in the copolymer. The thermal degradation activation energy values of the polymers were determined using approaches including the Kissinger and Ozawa methods. The result of the biological activity studies revealed that the copolymers show moderate activity against different bacterial and fungal species. The swelling properties of the polymers were investigated using water. The variations in the swelling percentages were examined according to time and temperature parameters.
Objective: Food allergies are an important factor causing hesitancy towards childhood
vaccines. This study aimed to investigate the effect of the COVID-19 pandemic
on vaccine hesitancy and vaccine ...refusal in children with food allergies.
Material and Methods: This study was conducted with 104 children and their parents,
who applied to the pediatric allergy clinic between October 1, 2020, and March
30, 2021. The children were classified as “fully vaccinated,” “incompletely vaccinated,”
and “unvaccinated.” Moreover, fully vaccinated children were divided into
two subgroups: “fully vaccinated on time” and “fully vaccinated with a delay.” Their
vaccination statuses and histories of COVID-19 were questioned. The Beck Anxiety
Scale was applied to the parents in the patient and control groups.
Results: Although there were no unvaccinated children, there were 12 (11.5%) incompletely
vaccinated children, 57 (54.8%) children who were fully vaccinated on
time, and 35 (33.6%) children who were fully vaccinated with a delay. Logistic regression
analysis determined that living outside the city center (OR: 6.9) and having a
family history of COVID-19 (OR: 5.8) caused a delay in vaccination. The analysis also
revealed that a high anxiety score (OR: 1.8) led to missed vaccinations.
Conclusion: The rate of delay in vaccination administration increased among individuals
living outside of a city center and those with a family history of COVID-19 infections.
It was also found that the rate of missed vaccinations increases with increased
parental anxiety.
We first present the salient features of the gravitational time dilation and redshift effects in two ways; by considering the oscillation frequencies/rates of clocks at different heights/potentials ...and by considering the photons emitted by these clocks such as atoms/nuclei. We then point out to the extension of these gravitational effects to static electricity along with two experiments performed in the '30s with null results of the electrostatic redshift. We show that the absence of this redshift is a consequence of the conservation of electric charge. We discuss the electrical time dilation and redshift effects in detail and argue that the electrostatic time dilation in an electric field must be a fact of Nature. We then present a general relativistic scheme that explains this effect. We also introduce an electrical equivalence principle analogous to the gravitational one and demonstrate how to obtain the electrostatic time dilation by this principle. We emphasize the importance of ionic atomic clocks to measure this effect whose confirmation would support the general relativistic scheme presented. We finally go over an attempt in the literature to explain the impossibility of the experimental observation of the electrostatic redshift due to its smallness by employing the Reissner - Nordström metric in general relativity. We argue that the Q2 - term in this metric is due to the minuscule contribution of the energy of the electric field of the central body to its gravitational field. Thus being gravitational, this metric cannot be used to calculate the amount of the alleged electrostatic redshift.
Purpose
To evaluate the effects of Duloxetine on anterior segment parameters and intraocular pressure (IOP) in open angle eyes.
Methods
38 eyes of 38 patients with fibromyalgia who had open or wide ...open angles according to the Shaffer classification. Anterior segment optic coherence tomography was performed before and after (month 3) Duloxetine treatment. IOP, central corneal thickness (CCT), corneal endothelial cell density (CECD) and anterior chamber depth (ACD) were also recorded and evaluated.
Results
No statistically significant difference was determined in IOP, CCT and CECD (
p
> 0.05). However, a statistically significant decrease was determined in both the temporal and nasal anterior chamber angle, angle opening distance, nasal trabecular-iris space area and ACD values between the baseline and month 3 (
p
< 0.001).
Discussion
We think that the short term use of Duloxetine does not lead to clinically significant changes despite their statistically significant effects on the anterior chamber parameters.
Amaç: Maksiller sinüs anatomisi hakkında yeterli bilgi, perioperatif veya postoperatif komplikasyonlardan kaçınmak için gereklidir. Bu çalışmanın amacı, konik ışınlı bilgisayarlı tomografi (KIBT) ile ...posterior superior alveolar arterin (PSAA) prevalansını, çapını, yerini ve maksiller sinüs tabanı ve alveolar kret ile ilişkisini belirlemektir.
Yöntem: Konik Işınlı Bilgisayarlı Tomografi görüntülemesi yapılmış 50 hastanın (100 maksiller sinüs) maksiller sinüsteki PSAA konumu ve çapları ile PSAA’nın lateral duvardaki alt noktası ile sinüs tabanı ve kret tepesi arasındaki mesafelerin cinsiyet ile ilişkisi retrospektif olarak değerlendirilmiştir. Tüm veriler SPSS versiyon 22.0 programı kullanılarak analiz edilmiştir. Sonuçlar p<0,05 için istatistiksel olarak anlamlı kabul edilmiştir.
Bulgular: PSAA, KIBT taramalarının %100'ünde tespit edilmiştir. Arterin yerleşim yeri ile cinsiyet arasında istatistiksel olarak anlamlı fark bulunmuştur (p=0,005). PSAA'nın kadınlarda %56, erkeklerde ise %34 oranında sinüs membranının altında yerleştiği saptanmıştır. PSAA'nın lateral sinüs duvarının dış korteksinde yerleşimi ise erkeklerde kadınlara oranla 10 kat daha fazla bulunmuştur. Ortalama PSAA çapı 1,07 mm olarak ölçülmüştür. PSAA’nın alt sınırı ile sinüs tabanı arasında dik olarak ölçülen ortalama mesafe 8,30±4,17 mm, oblik olarak ölçülen ortalama mesafe 9,26±4,34 mm idi. PSAA’nın alt sınırı ile kret tepesi arasında dik olarak yapılan ölçümlerdeki ortalama mesafe 16,66±5,17 mm, oblik olarak ölçülen ortalama mesafe ise 18,36±4,84 mm olarak bulunmuştur. Sonuç: Bu çalışmadan elde edilen bulgular, PSAA konumu ve PSAA ile maksiller sinüs tabanı arasındaki mesafenin cinsiyete göre farklılık gösterebileceğini düşündürmüştür. Bu yönlerden KIBT'lerin preoperatif değerlendirilmesi tedavi planı ve başarısı açısından oldukça önemlidir.
The purpose of this study is to explore effects of team enablers (team autonomy and organizational support) and team cohesion dimensions
on project team success and the mediating effect of team ...cohesion dimensions in this relation. Partial Least Squares Structural Equation
Model (PLS-SEM) was used in the study conducted on 110 project teams which had 343 team members in a multinational financial
institution. Reliability of the measures were calculated by Cronbach Alpha (α) coefficient and validity of the measures were calculated by
exploratory and confirmatory factor analyses. As the unit of analysis is “project team”, the question items were aggregated to team level by
calculating the arithmetic mean and inter-rater agreement values (rwg) were checked for reliability. The findings of the research revealed
that organizational support was a significant antecedent of team task cohesion and team effectiveness. Team task cohesion was found to
have a partial mediating role in the relationship between organizational support and team effectiveness. In addition, although the
significant positive effects of team autonomy on project team success dimensions were confirmed, none of the dimensions of team cohesion
had a significant relationship with team autonomy. In accordance with the literature, positive effects of task cohesion on team effectiveness
and team innovation were supported, however the effect of social cohesion on project team success was not significant.
To prospectively examine the effects of selective laser trabeculoplasty (SLT) on the anterior chamber angle (ACA) and its related parameters using anterior segment-optic coherence tomography ...(AS-OCT). Fifty eyes of 50 patients with primary open angle glaucoma (POAG) and ocular hypertension were included in the study. AS-OCT was performed before SLT application, immediately after and at 1 day and 1 month. Intraocular pressure (IOP), central corneal thickness (CCT) and anterior chamber depth (ACD) were also recorded and evaluated. No statistically significant difference was determined in ACA and other AS-OCT parameters (AOD, angle opening distance at 500 and 750 mm; TISA, trabecular-iris space area at 500 and 750 mm) before and 1 day after SLT application (
p
> 0.05). However, a statistically significant increase was determined in both the temporal and nasal ACA, AOD and TISA values between the baseline and day 30 (
p
< 0.001). No statistically significant change was observed in the CCT or ACD values (
p
> 0.05). SLT resulted in an increase in ACA, AOD and TISA when evaluated using AS-OCT. We think that this study provides a different perspective concerning the effects of SLT in the angle region and the involved mechanism.
Aim: To evaluate the strain ratio of the optic nerve and retina-choroid-sclera (RCS) layers in individuals with physiological optic disc cupping (PC) and glaucoma patients using strain ...elastography.Material and methods: We evaluated 56 eyes of 56 subjects (20 eyes with glaucoma, 19 eyes with PC, and 17 normal eyes). The strain ratio of orbital fat to optic nerve (SROFON) was calculated as the ratio of the optic nerve to intraconal fat tissue and the strain ratio of orbital fat to retina-choroid-sclera (SROFRCS) was calculated as the ratio of RCS layers to intraconal fat tissue.Results: SROFON was 0.92 in the control group, 1.07 in the PC group and 1.6 in the glaucoma group and a statistically significant difference was present between the three groups (p<0.05). SROFRCS had no statistically significant difference between the three groups.Conclusions: SROFON values could contribute to the differentiation of the patients with glaucoma and PC.
Purpose: To determine the role of Molsidomine in preventing radiation-induced retinopathy after head and neck region irradiation of rats with a single radiation dose of 15 Gy.
Materials and Methods: ...Male Wistar albino rats were randomly grouped into five as follows: (1) control group rats, which were applied through an intraperitoneal (i.p.) vehicle without radiotherapy (RT); (2) RT group rats received a single dose of 15 Gy irradiation and after daily 0.1 ml vehicle i.p. for 5 consecutive days; (3) molsidomine (MOL) group rats were treated for 5 consecutive days by i.p. with 4 mg/kg/day MOL; (4) irradiation plus MOL group (RT+MOL) rats received irradiation and after 10 days single daily i.p. dose of MOL for 5 consecutive days; and (5) MOL+RT group rats were treated for 5 consecutive days by i.p. with MOL before RT. At the end of the work the rats were sacrificed under high-dose anesthesia on the 16
th
day and then eye tissues were taken for histopathological, immunohistochemical (caspase-3), and biochemical analyses (superoxide dismutase SOD, glutathione peroxidase GSH, and malondialdehyde MDA).
Results: RT significantly decreased both the content of GSH and the activity of SOD, and significantly increased the production of MDA level in the rat eyes. MOL treatment significantly increased the SOD and GSH levels and significantly decreased the MDA production (p < 0.0001). In addition, RT significantly increased the number of ganglion cells (GCs; p = 0.001), whereas especially pretreatment with MOL improved (p = 0.013). RT led to significant retinopathy formation, and MOL therapy protected the retina from radiation-induced retinopathy (p < 0.0001).
Conclusions: We suggest that MOL is a powerful antioxidant and free radical scavenger that prevents the rat eyes from radiation-induced retinopathy and oxidative stress.
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