During the upcoming Run 3 and Run 4 at the LHC the upgraded ALICE (A Large Ion Collider Experiment) will operate at a significantly higher luminosity and will collect two orders of magnitude more ...events than in Run 1 and Run 2. A part of the ALICE upgrade is the new Fast Interaction Trigger (FIT). This thoroughly redesigned detector combines, in one system, the functionality of the four forward detectors used by ALICE during the LHC Run 2: T0, V0, FMD, and AD. The FIT will monitor luminosity and background, provide feedback to the LHC, and generate minimum bias, vertex and centrality triggers, in real time. During the offline analysis FIT data will be used to extract the precise collision time needed for time-of-flight (TOF) particle identification. During the heavy-ion collisions, FIT will also determine multiplicity, centrality, and event plane. The FIT electronics is designed to function both in the continuous and the triggered readout mode. In these proceedings the FIT simulation, software, and raw data processing are briefly described. However, the main focus is on the detector performance, trigger efficiencies, collision time, and centrality resolution.
Determine the primary antibiotic resistance of Helicobacter pylori (H. pylori) strains isolated from patients living in the European part of the Russian Federation.
As part of a clinical laboratory ...study, from 2015 to 2018, 27 gastrobiopsy samples obtained from H. pylori-infected patients were analyzed. H. pylori infection was verified using a rapid urease test or a 13C-urea breath test. The values of the minimum inhibitory concentration (MIC) of antibiotics were determined by the diffusion method using E-test strips (BioMerieux, France) according to the recommendations of the manufacturer. The sensitivity of the isolates was determined for 6 antibacterial drugs (amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, rifampicin).
According to the data obtained, resistance to amoxicillin was 0%, clarithromycin 11.1%, metronidazole 59.3%, levofloxacin 3.7%, tetracycline 0%, and rifampicin 14.8%. Dual resistance to clarithromycin and metronidazole was recorded in two isolates (7.4%).
Thus, the first results of the evaluation of H. pylori antibiotic resistance in the European part of the Russian Federation indicate a low resistance of the microorganism to clarithromycin and quite high to metronidazole.
Introduction
In esthetic surgery, the use of silicone implants is a topic of hot discussion.
Material and methods
An analysis of 119 esthetic surgical interventions on the mammary gland was ...performed. A study of the immune and endocrine parameters after mammoplasty was carried out.
Results
The phenomenon of an increase in the levels of autoantibodies to the TSH receptor was revealed. The phenomenon of pre-operative growth of prolactin and TSH levels has been confirmed. An increase in thyroid autoimmunity after silicone mammoplasty is interpreted as a result of a silicone adjuvant action. An increase in the incidence of ASIA syndrome in patients who underwent breast surgery was registered. However, it was observed in both patients with silicone and non-silicone breast surgeries and therefore could not be solely explained by the use of silicone. Within 12 months following silicone mammoplasty, the patients with an increase of anti-TSH receptor autoimmunity nevertheless did not show any clinical and laboratory signs of overt thyroid disease, thus staying in a pre-nosological state.
Practical recommendations
Based on these results, we recommend the following for esthetic surgery: (a) all patients planned for silicone implant surgery should be examined for autoantibodies to the TSH receptor and (b) patients who have undergone breast endoprosthesis, starting 6 months after the operation, need long-term follow-up for thyroid status with mandatory testing for the level of these autoantibodies.
ALICE T0 detector Bondila, M.; Grigoriev, V.A.; Guber, F.F. ...
IEEE transactions on nuclear science,
10/2005, Volume:
52, Issue:
5
Journal Article
Peer reviewed
T0-the fast timing and trigger detector for the ALICE experiment at CERN LHC-is described. Performance of the T0 prototype measured with a mixture of 6 GeV/c negative pions and kaons is given. The ...best time resolution (28 ps r.m.s.) was reached with a radiator diameter matching that of the photocathode. The results for all the tested radiator sizes are considerably better than 50 ps-the minimum requirement for the ALICE experiment.
ALICE (A Large Ion Collider Experiment) experiment at CERN LHC is designed to study the properties of the Quark-Gluon Plasma (QGP) in heavy-ion collisions. In 2019-2020 the upgrade of CERN LHC will ...increase the luminosity and the collision rate beyond the design parameters of the current ALICE setup. To be able to benefit from the improved performance of the LHC, ALICE will upgrade several of its key detector systems including the Fast Interaction Trigger (FIT) 2. FIT is designed to provide the functionality of the old forward detectors while retaining or even improving their performance. It will provide Minimum Bias trigger with efficiency higher than 90% for pp collisions, measure luminosity for pp and Pb-Pb, sustain interaction rates up to 1MHz and 50kHz, respectively. FIT will determine the collision time with a resolution better than 50ps, and will be used to measure the event multiplicity, the centrality and the reaction plane. The detector consists of 2 arrays of Cherenkov radiators with MCP-PMT sensors, placed on both sides of the interaction point and of a single large-diameter scintillator ring. This presentation will discuss the main design concepts, detector construction, beam test results, MC simulations, and the results of detector performance studies.
The cross sections of forward emission of one, two and three neutrons by 158A GeV 115In nuclei in collisions with Al, Cu, Sn and Pb targets are reported. The measurements were performed in the ...framework of the ALICE–LUMI experiment at the SPS facility at CERN. Various corrections accounting for the absorption of beam nuclei and produced neutrons in target material and surrounding air were introduced. The corrected cross section data are compared with the predictions of the RELDIS model for electromagnetic fragmentation of 115In in ultraperipheral collisions, as well as with the results of the abrasion–ablation model for neutron emission in hadronic interactions. The measured neutron emission cross sections well agree with the RELDIS results, with the exception of In–Al collisions where the measured cross sections are larger compared to RELDIS. This is attributed to a relatively large contribution of hadronic fragmentation of In on Al target with respect to electromagnetic fragmentation, in contrast to similar measurements performed earlier with 30A GeV 208Pb colliding with Al.
Development of a RICH detector for electron identification in CBM Höhne, C.; Das, S.; Dürr, M. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
09/2008, Volume:
595, Issue:
1
Journal Article
Peer reviewed
The Compressed Baryonic Matter (CBM) experiment at the future FAIR accelerator at Darmstadt, Germany, will investigate baryonic matter at highest net-baryon densities but moderate temperatures by ...colliding nuclei at beam energies from 8 to 45
AGeV. One of the key observables are low-mass vector mesons and charmonium decaying into lepton pairs. For electron identification a RICH detector is foreseen. In this contribution detector simulations, feasibility studies and first steps in the detector development are discussed.
The paper considers the possibilities of using the Moodle learning management system when studying English at university. The peculiarities of teaching students a foreign language in a non-language ...university and the possibilities of increasing the effectiveness of learning by using distance (electronic) learning in comparison with the face-to-face format of similar labor intensity are noted. Written skills and abilities in the use of a foreign language are one of the important aspects of communicative competence. They are necessary for practical mastery of everyday speech and the language of specialty. The possibilities of learning management systems and distance learning facilitate the work of the teacher. The developed special interactive exercises are aimed at accelerated formation of students' written skills as part of their foreign language communicative competence.
The application of micro-pixel Avalanche photodiodes (MAPD) for the readout of hadron calorimeters is discussed. A prototype calorimeter was constructed consisting of individual lead/scintillator ...sandwich modules with a sampling satisfying the compensating condition. The light from each scintillator tile is captured and transported with WLS fibers embedded in the scintillator and extended to the rear end of the module. A set of 6 WLS fibers from neighboring tiles is grouped in one bundle and viewed by a 3×3
mm
2 avalanche micro-pixel photodiode. The design provides a longitudinal segmentation of the module into 10 sections with independent MAPD readout. Use of MAPDs with pixel density 10
4/mm
2 ensures good linearity of calorimeter response over a wide dynamical range. The performance of the calorimeter prototype in beam tests is reported.
Usage of electrodes made of glass with low bulk resistivity seems to be a promising way to adapt the Resistive Plate Chambers (RPC) to the high-rate environment of the upcoming CBM experiment. A ...pilot four-gap RPC sample with electrodes made of phosphate glass, which has bulk resistivity in the order of 1010Ωcm, has been studied with MIP beam for TOF applications. The tests have yielded satisfactory results: the efficiency remains above 95% and the time resolution stays within 120ps up to the particle rate of 18kHz/cm2. The increase in rate from 2.25 to 18kHz/cm2 leads to an increase of estimated tails fraction in the time spectrum from 1.5% to 4%.
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