Context. With the space-borne missions CoRoT and Kepler, a large amount of asteroseismic data is now available and has led to a variety of work. So-called global oscillation parameters are inferred ...to characterize the large sets of stars, perform ensemble asteroseismology, and derive scaling relations. The mean large separation is such a key parameter, easily deduced from the radial-frequency differences in the observed oscillation spectrum and closely related to the mean stellar density. It is therefore crucial to measure it with the highest accuracy in order to obtain the most precise asteroseismic indices. Aims. As the conditions of measurement of the large separation do not coincide with its theoretical definition, we revisit the asymptotic expressions used for analyzing the observed oscillation spectra. Then, we examine the consequence of the difference between the observed and asymptotic values of the mean large separation. Methods. The analysis is focused on radial modes. We use series of radial-mode frequencies in published analyses of stars with solar-like oscillations to compare the asymptotic and observational values of the large separation. This comparison relies on the proper use of the second-order asymptotic expansion. Results. We propose a simple formulation to correct the observed value of the large separation and then derive its asymptotic counterpart. The measurement of the curvature of the radial ridges in the échelle diagram provides the correcting factor. We prove that, apart from glitches due to stellar structure discontinuities, the asymptotic expansion is valid from main-sequence stars to red giants. Our model shows that the asymptotic offset is close to 1/4, as in the theoretical development, for low-mass, main-sequence stars, subgiants and red giants. Conclusions. High-quality solar-like oscillation spectra derived from precise photometric measurements are definitely better described with the second-order asymptotic expansion. The second-order term is responsible for the curvature observed in the échelle diagrams used for analyzing the oscillation spectra, and this curvature is responsible for the difference between the observed and asymptotic values of the large separation. Taking it into account yields a revision of the scaling relations, which provides more accurate asteroseismic estimates of the stellar mass and radius. After correction of the bias (6% for the stellar radius and 3% for the mass), the performance of the calibrated relation is about 4% and 8% for estimating, respectively, the stellar radius and the stellar mass for masses less than 1.3 M⊙; the accuracy is twice as bad for higher mass stars and red giants.
Context. CoRoT is a space telescope dedicated to stellar seismology and the search for extrasolar planets. The mission is led by the CNES in association with French laboratories and has a large ...international participation. The European Space Agency (ESA), Austria, Belgium, and Germany contribute to the payload, and Spain and Brazil contribute to the ground segment. Development of the spacecraft, which is based on a PROTEUS low earth orbit (LEO) recurrent platform, commenced in October 2000, and the satellite was launched on December 27, 2006. Aims. The instrument and platform characteristics prior to launch have been described in ESA publication (SP-1306). In the present paper we explain the behaviour in flight, based on raw and corrected data. Methods. Five runs have been completed since January 2007. The data used here are essentially those acquired during the commissioning phase and from a long run that lasted 146 days. These enable us to give a complete overview of the instrument and platform behaviour for all environmental conditions. The ground based data processing is not described in detail because the most important method has been published elsewhere. Results. We show that the performance specifications are easily satisfied when the environmental conditions are favourable. Most of the perturbations, hence data corrections, are related to LEO perturbations: high energy particles inside the South Atlantic Anomaly (SAA), eclipses and temperature variations, and line of sight fluctuations due to the attitude control system. Straylight due to the reflected light from the earth, which is controlled by the telescope and baffle design, appears to be negligible.
Context. The CoRoT 5-month long observation runs provide us with the opportunity to analyze a large variety of red-giant stars and derive their fundamental parameters from their asteroseismic ...properties. Aims. We perform an analysis of more than 4600 CoRoT light curves to extract as much information as possible. We take into account the characteristics of both the star sample and the method to ensure that our asteroseismic results are as unbiased as possible. We also study and compare the properties of red giants in two opposite regions of the Galaxy. Methods. We analyze the time series using the envelope autocorrelation function to extract precise asteroseismic parameters with reliable error bars. We examine first the mean wide frequency separation of solar-like oscillations and the frequency of the maximum seismic amplitude, then the parameters of the excess power envelope. With the additional information of the effective temperature, we derive the stellar mass and radius. Results. We identify more than 1800 red giants among the 4600 light curves and obtain accurate distributions of the stellar parameters for about 930 targets. We are able to reliably measure the mass and radius of several hundred red giants. We derive precise information about the stellar population distribution and the red clump. By comparing the stars observed in two different fields, we find that the stellar asteroseismic properties are globally similar, but that the characteristics are different for red-clump stars. Conclusions. This study demonstrates the efficiency of statistical asteroseismology: validating scaling relations allows us to infer fundamental stellar parameters, derive precise information about red-giant evolution and interior structure, analyze and compare stellar populations from different fields.
We report on an intensive observational campaign carried out with HARPS at the 3.6 m telescope at La Silla on the star CoRoT-7. Additional simultaneous photometric measurements carried out with the ...Euler Swiss telescope have demonstrated that the observed radial velocity variations are dominated by rotational modulation from cool spots on the stellar surface. Several approaches were used to extract the radial velocity signal of the planet(s) from the stellar activity signal. First, a simple pre-whitening procedure was employed to find and subsequently remove periodic signals from the complex frequency structure of the radial velocity data. The dominant frequency in the power spectrum was found at 23 days, which corresponds to the rotation period of CoRoT-7. The 0.8535 day period of CoRoT-7b planetary candidate was detected with an amplitude of 3.3 m s-1. Most other frequencies, some with amplitudes larger than the CoRoT-7b signal, are most likely associated with activity. A second approach used harmonic decomposition of the rotational period and up to the first three harmonics to filter out the activity signal from radial velocity variations caused by orbiting planets. After correcting the radial velocity data for activity, two periodic signals are detected: the CoRoT-7b transit period and a second one with a period of 3.69 days and an amplitude of 4 m s-1. This second signal was also found in the pre-whitening analysis. We attribute the second signal to a second, more remote planet CoRoT-7c . The orbital solution of both planets is compatible with circular orbits. The mass of CoRoT-7b is $4.8\pm0.8$ ($M_{\oplus}$) and that of CoRoT-7c is $8.4\pm 0.9$ ($M_{\oplus}$), assuming both planets are on coplanar orbits. We also investigated the false positive scenario of a blend by a faint stellar binary, and this may be rejected by the stability of the bisector on a nightly scale. According to their masses both planets belong to the super-Earth planet category. The average density of CoRoT-7b is $\rho=5.6\pm 1.3\mathrm{\,g\,cm^{-3}}$, similar to the Earth. The CoRoT-7 planetary system provides us with the first insight into the physical nature of short period super-Earth planets recently detected by radial velocity surveys. These planets may be denser than Neptune and therefore likely made of rocks like the Earth, or a mix of water ice and rocks.
Glial progenitor cells (GPCs) are a potential source of malignant gliomas. We used A2B5-based sorting to extract tumorigenic GPCs from human gliomas spanning World Health Organization grades II–IV. ...Messenger RNA profiling identified a cohort of genes that distinguished A2B5+ glioma tumor progenitor cells (TPCs) from A2B5+ GPCs isolated from normal white matter. A core set of genes and pathways was substantially dysregulated in A2B5+ TPCs, which included the transcription factor SIX1 and its principal cofactors, EYA1 and DACH2. Small hairpin RNAi silencing of SIX1 inhibited the expansion of glioma TPCs in vitro and in vivo, suggesting a critical and unrecognized role of the SIX1-EYA1-DACH2 system in glioma genesis or progression. By comparing the expression patterns of glioma TPCs with those of normal GPCs, we have identified a discrete set of pathways by which glial tumorigenesis may be better understood and more specifically targeted.
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•Gene expression in normal versus neoplastic A2B5+ glioma tumor progenitor cells (TPCs) was profiled•A2B5+ TPCs transit from proneural to mesenchymal phenotype with glioma progression•SIX1 and EYA1 are overexpressed in A2B5+ TPCs at all stages of glioma progression•Inhibition of SIX1 suppresses glioma TPC expansion in vitro and in vivo
A discrete fraction of tumor progenitor cells (TPCs) may be responsible for the initiation, recurrence, and treatment resistance of glioma. To identify pathways to treat these tumors, Auvergne, Goldman, and colleagues compared the expression profiles of A2B5-defined glioma TPCs at varying stages of progression with those of normal adult human glial progenitor cells. They identify a discrete cohort of genes and pathways that are associated with the earliest stages of glioma formation and are maintained throughout progression. Targeting these pathways may permit more effective glioma treatment.
Context. The first asteroseismology results from CoRoT are presented, on a star showing Sun-like oscillations. We have analyzed a 60 day lightcurve of high-quality photometric data collected by CoRoT ...on the F5 V star HD 49933. The data reveal a rich spectrum of overtones of low-degree p modes. Aims. Our aim was to extract robust estimates of the key parameters of the p modes observed in the power spectrum of the lightcurve. Methods. Estimation of the mode parameters was performed using maximum likelihood estimation of the power spectrum. A global fitting strategy was adopted whereby 15 mode orders of the mode spectrum (45 modes) were fitted simultaneously. Results. The parameter estimates that we list include mode frequencies, peak linewidths, mode amplitudes, and a mean rotational frequency splitting. We find that the average large frequency (overtone) spacing derived from the fitted mode frequencies is 85.9 ± 0.15 μHz. The frequency of maximum amplitude of the radial modes is at 1760 μHz, where the observed rms mode amplitude is 3.75 ± 0.23 ppm. The mean rotational splitting of the non-radial modes appears to be in the range ≈2.7 μHz to ≈3.4 μHz. The angle of inclination offered by the star, as determined by fits to the amplitude ratios of the modes, appears to be in the range ≈50 degrees to ≈62 degrees.
Aims: The CoRoT and Kepler satellites have provided thousands of red-giant oscillation spectra. The analysis of these spectra requires efficient methods of identifying all eigenmode parameters. ...Methods: The assumption of new scaling laws allowed us to construct a theoretical oscillation pattern. We then obtained a highly precise determination of the large separation by correlating the observed patterns with this reference. Results: We demonstrate that this pattern is universal and are able to unambiguously assign the eigenmode radial orders and angular degrees. This solves one of the remaining problems of asteroseismology, hence allowing precise theoretical investigation of red-giant interiors.
Context. The detection of pulsational frequencies in stellar photometry is required as input for asteroseismological modelling. The second short run (SRa02) of the CoRoT mission has provided ...photometric data of unprecedented quality and time-coverage for a number of O-type stars. Aims: We analyse the CoRoT data corresponding to three hot O-type stars, describing the properties of their light curves and search for pulsational frequencies, which we then compare to theoretical model predictions. Methods: We determine the amplitude spectrum of the data, using the Lomb-Scargle and a multifrequency HMM-like technique. Frequencies are extracted by prewhitening, and their significance is evaluated under the assumption that the light curve is dominated by red noise. We search for harmonics, linear combinations, and regular spacings among these frequencies. We use simulations with the same time sampling as the data as a powerful tool to judge the significance of our results. From the theoretical point of view, we use the MAD non-adiabatic pulsation code to determine the expected frequencies of excited modes. Results: A substantial number of frequencies is listed, but none can be convincingly identified as being connected to pulsations. The amplitude spectrum is dominated by red noise. Theoretical modelling shows that all three O-type stars can have excited modes, but the relation between the theoretical frequencies and the observed spectrum is not obvious. Conclusions: The dominant red noise component in the hot O-type stars studied here clearly points to a different origin than the pulsations seen in cooler O stars. The physical cause of this red noise is unclear, but we speculate on the possibility of sub-surface convection, granulation, or stellar wind inhomogeneities being responsible.
Context. The star HD 49385 is the first G-type solar-like pulsator observed in the seismology field of the space telescope CoRoT. The satellite collected 137 days of high-precision photometric data ...on this star, confirming that it presents solar-like oscillations. HD 49385 was also observed in spectroscopy with the NARVAL spectrograph in January 2009. Aims. Our goal is to characterize HD 49385 using both spectroscopic and seismic data. Methods. The fundamental stellar parameters of HD 49385 are derived with the semi-automatic software VWA, and the projected rotational velocity is estimated by fitting synthetic profiles to isolated lines in the observed spectrum. A maximum likelihood estimation is used to determine the parameters of the observed p modes. We perform a global fit, in which modes are fitted simultaneously over nine radial orders, with degrees ranging from $\ell$ = 0 to $\ell$ = 3 (36 individual modes). Results. Precise estimates of the atmospheric parameters (Teff, M/H, log g) and of the ν sin i of HD 49385 are obtained. The seismic analysis of the star leads to a clear identification of the modes for degrees $\ell$ = 0,1,2. Around the maximum of the signal (ν $\simeq$ 1013 μHz), some peaks are found significant and compatible with the expected characteristics of $\ell$ = 3 modes. Our fit yields robust estimates of the frequencies, linewidths and amplitudes of the modes. We find amplitudes of ~5.6 ± 0.8 ppm for radial modes at the maximum of the signal. The lifetimes of the modes range from one day (at high frequency) to a bit more than two days (at low frequency). Significant peaks are found outside the identified ridges and are fitted. They are attributed to mixed modes.
Context. The CoRoT satellite has recently discovered the transits of an Earth-like planet across the disc of a late-type magnetically active star dubbed CoRoT-7, while a second planet was detected ...after filtering out the radial velocity (hereafter RV) variations due to stellar activity. Aims. We investigate the magnetic activity of CoRoT-7 and use the results for a better understanding of the impact of magnetic activity on stellar RV variations. Methods. We derived the longitudinal distribution of active regions on CoRoT-7 from a maximum entropy spot model of the CoRoT lightcurve. Assuming that each active region consists of dark spots and bright faculae in a fixed proportion, we synthesized the expected RV variations. Results. Active regions are mainly located at three active longitudes that appear to migrate at different rates, probably as a consequence of surface differential rotation, for which a lower limit of ΔΩ/Ω = 0.058 ± 0.017 is found. The synthesized activity-induced RV variations reproduce the amplitude of the observed RV curve and are used to study the impact of stellar activity on planetary detection. Conclusions. In spite of the non-simultaneous CoRoT and HARPS observations, our study confirms the validity of the method previously adopted to filter out RV variations induced by stellar activity. We find a false-alarm probability <10-4 that the RV oscillations attributed to CoRoT-7b and CoRoT-7c are spurious effects of noise and activity. Additionally, our model suggests that other periodicities found in the observed RV curve of CoRoT-7 could be explained by active regions whose visibility is modulated by a differential stellar rotation with periods ranging from 23.6 to 27.6 days.