We propose to analyze ellipsometry data by using effective medium approximation (EMA) models. Thanks to EMA, having nanocrystalline reference dielectric functions and generalized critical point (GCP) ...model the physical parameters of two series of samples containing silicon nanocrystals, i.e. silicon rich oxide (SRO) superlattices and porous silicon layers (PSL), have been determined. The superlattices, consisting of ten SRO/SiO2 layer pairs, have been prepared using plasma enhanced chemical vapor deposition. The porous silicon layers have been prepared using short monopulses of anodization current in the transition regime between porous silicon formation and electropolishing, in a mixture of hydrofluoric acid and ethanol. The optical modeling of both structures is similar. The effective dielectric function of the layer is calculated by EMA using nanocrystalline components (nc-Si and GCP) in a dielectric matrix (SRO) or voids (PSL). We discuss the two major problems occurring when modeling such structures: (1) the modeling of the vertically non-uniform layer structures (including the interface properties like nanoroughness at the layer boundaries) and (2) the parameterization of the dielectric function of nanocrystals. We used several techniques to reduce the large number of fit parameters of the GCP models. The obtained results are in good agreement with those obtained by X-ray diffraction and electron microscopy. We investigated the correlation of the broadening parameter and characteristic EMA components with the nanocrystal size and the sample preparation conditions, such as the annealing temperatures of the SRO superlattices and the anodization current density of the porous silicon samples. We found that the broadening parameter is a sensitive measure of the nanocrystallinity of the samples, even in cases, where the nanocrystals are too small to be visible for X-ray scattering. Major processes like sintering, phase separation, and intermixing have been revealed as a function of annealing of the SRO superlattices.
We have developed prototypes of GEM-like detectors with resistive electrodes to be used as RICH photodetectors equipped with CsI photocathodes. The main advantages of these detectors are their ...intrinsic spark-protection and possibility to operate at high gain (∼10
5) in many gases including poorly quenched ones, allowing for the adoption of windowless configurations in which the radiator gas is also used in the chamber. Results of systematic studies of the resistive GEMs combined with CsI photocathodes are presented: their quantum efficiency, rate characteristics, long-term stability, etc. On the basis of the obtained results, we believe that the new detector will be a promising candidate for upgrading the ALICE RICH detector.
A small-size prototype of a new Ring Imaging Cherenkov (RICH) detector using for the first time pressurized C4F8O radiator gas and a photon detector consisting of MWPC equipped with a CsI ...photocathode has been built and tested at the PS accelerator at CERN. It contained all the functional elements of the detector proposed as Very High Momentum Particle Identification (VHMPID) upgrade for the ALICE experiment at LHC to provide charged hadron track-by-track identification in the momentum range starting from 5 potentially up to 25GeV/c. In the paper the equipment and its elements are described and some characteristic test results are shown.
Jet-matter interaction remains a central question and a theoretical challenge in heavy-ion physics and might become important in high-multiplicity events in proton-proton collisions at LHC energies. ...Full jet measurement at LHC offer the proper tool to investigate energy loss process and fragmentation of hard parton in the medium. Since jet reconstruction will be constrained to small cone sizes, then study of the connection between jets and surrounding environment provides a further possibility to extend our exploration. We study jets at 14 TeV and pp collisions at 7 TeV. We analyze the flavor components in jet-like environments. We introduce a definition for surrounding cones/belts and investigate flavor dependence and correlation of different hadron species produced in jets. Here, we focus on proton-triggered correlations. Our analysis can be extended for heavy ion collisions.
Recent experimental studies have revealed that lymphangiogenesis plays an important role in cancer progression, but its clinical significance in the case of non-small cell lung cancer (NSCLC) remains ...unclear. Our aim was to assess the lymphangiogenesis of human NSCLC, and to correlate this with angiogenic phenotype (angiogenic versus nonangiogenic growth pattern) and clinical behavior.
One hundred and three patients with NSCLC and complete follow-up information were included. Tumor samples were immunostained for vascular endothelial growth factor-C (VEGF-C), the lymphatic endothelial markers, LYVE-1 and D2-40/Podoplanin, and the panvascular marker, CD31. Lymphatic vessel density (LVD) and perimeters were evaluated within the tumor and peritumorally.
LVDs at the tumor periphery were significantly higher in lymph node metastatic tumors (P < 0.005) and high LVDs correlated with poor overall survival (P < 0.001). However, this tendency proved to be significant only in the angiogenic tumor group (P < 0.001). Although 68% of the patients with nonangiogenic tumors had lymph node metastasis (P = 0.0048 versus angiogenic tumors), in the patient group with nonangiogenic NSCLCs, there was no information from the LVDs in any investigated tumor area (P > 0.05). In contrast to angiogenic tumors, which had actively sprouting lymphatics in all of the investigated tumor areas, nonangiogenic tumors showed no Ki67 staining intratumorally.
Our results reveal tumor lymphangiogenesis as a novel prognostic indicator for the risk of lymph node metastasis in NSCLC. Moreover, it also provides the first evidence that nonangiogenic NSCLCs mainly co-opt host tissue lymphatics during their growth, in contrast to most of the angiogenic tumors, which expand with concomitant lymphangiogenesis.
We report on the R&D results for a Very High Momentum Particle Identification (VHMPID) detector, which was proposed to extend the charged hadron track-by-track identification in the momentum range ...from 5 to 25 GeV/c in the ALICE experiment at CERN. It is a RICH detector with focusing geometry using pressurized perfluorobutane (C sub(4)F sub(8)O) as a Cherenkov radiator. A MWPC with a CsI photocathode was investigated as the baseline option for the photon detector. The results of beam tests performed on RICH prototypes using both liquid C sub(6)F sub(14) radiator (in proximity focusing geometry for reference measurements) and pressurized C sub(4)F sub(8)O gaseous radiator will be shown in this paper. In addition, we present studies of a CsI based gaseous photon detector equipped with a MWPC having an adjustable anode-cathode gap, aiming at the optimization of the chamber layout and performance in the detection of single photoelectrons.
Context.
Optical interferometry is at a key development stage. The Very Large Telescope Interferometer (VLTI) has established a stable, robust infrastructure for long-baseline interferometry that is ...usable by general astronomical observers. The present second-generation instruments offer a wide wavelength coverage and improved performance. Their sensitivity and measurement accuracy lead to data and images of high reliability.
Aims.
We have developed the Multi AperTure mid-Infrared SpectroScopic Experiment (MATISSE) to access, for the first time, high resolution imaging in a wide spectral domain. Many front-line topics are explored with this new equipment, including: stellar activity and mass loss; planet formation and evolution in the gas and dust disks around young stars; and environment interaction and accretion processes around super massive black holes in active galactic nuclei.
Methods.
The instrument is a spectro-interferometric imager in the transmission windows called
L
,
M
, and
N
, from 2.8 to 13.0 microns, combining four optical beams from the VLTI’s unit or auxiliary telescopes. Its concept, related observing procedure, data reduction, and calibration approach, is the product of 30 years of instrumental research and has benefitted from the expertise developed in the frame of the VLTI’s first generation instruments. The instrument utilises a multi-axial beam combination that delivers spectrally dispersed fringes. The signal provides the following quantities at several spectral resolutions: photometric flux, coherent fluxes, visibilities, closure phases, wavelength differential visibilities and phases, and aperture-synthesis imaging.
Results.
This article provides an overview of the physical principle of the instrument and its functionalities. The motivation of the choice of the instrumental concept and the characteristics of the delivered signal are detailed with a description of the observing modes and of their performance limit. MATISSE offers four spectral resolutions in
L
&
M
bands, namely 30, 500, 1000 and 3400, and 30 and 220 in the
N
band, and it provides an angular resolution down to 3 mas for the shortest wavelengths. The MATISSE stand-alone sensitivity limits are 60 mJy in
L
and 300 mJy in
N
. The paper gives details of the sensitivity limits for the different measurables and their related precision criteria, considering telescope configurations and spectral resolutions. We also discuss the gain provided with the GRA4MAT fringe tracker. An ensemble of data and reconstructed images illustrate the first acquired key observations.
Conclusions.
The instrument has been in operation at Cerro Paranal, ESO, Chile, since 2018, and has been open for science use by the international community since April 2019. The first scientific results are being published now.
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