The intermediate-mass star β Pictoris is known to be surrounded by a structured edge-on debris disk within which a gas giant planet was discovered orbiting at 8−10 AU. The physical properties of β ...Pic b were previously inferred from broad- and narrow-band 0.9−4.8 μm photometry. We used commissioning data of the Gemini Planet Imager (GPI) to obtain new astrometry and a low-resolution (R ~ 35−39) J-band (1.12−1.35 μm) spectrum of the planet. We find that the planet has passed the quadrature. We constrain its semi-major axis to ≤10 AU (90% prob.) with a peak at 8.9+0.4-0.6 AU. The joint fit of the planet astrometry and the most recent radial velocity measurements of the star yields a planet dynamical mass lower than 20 MJup (≥96% prob.). The extracted spectrum of β Pic b is similar to those of young L1-1.5+1 dwarfs. We used the spectral type estimate to revise the planet luminosity to log (L/L⊙) = −3.90 ± 0.07. The 0.9−4.8 μm photometry and spectrum are reproduced for Teff = 1650 ± 150 K and a log g ≤ 4.7 dex by 12 grids of PHOENIX-based and LESIA atmospheric models. For the most recent system age estimate (21 ± 4 Myr), the bolometric luminosity and the constraints on the dynamical mass of β Pic b are only reproduced by warm- and hot-start tracks with initial entropies Si> 10.5 kB/baryon. These initial conditions may result from an inefficient accretion shock and/or a planetesimal density at formation higher than in the classical core-accretion model. Considering a younger age for the system or a conservative formation time for β Pic b does not change these conclusions.
Context. PDS 70 is a young (5.4 Myr), nearby (~113 pc) star hosting a known transition disk with a large gap. Recent observations with SPHERE and NACO in the near-infrared (NIR) allowed us to detect ...a planetary mass companion, PDS 70 b, within the disk cavity. Moreover, observations in Hα with MagAO and MUSE revealed emission associated to PDS 70 b and to another new companion candidate, PDS 70 c, at a larger separation from the star. PDS 70 is the only multiple planetary system at its formation stage detected so far through direct imaging. Aims. Our aim is to confirm the discovery of the second planet PDS 70 c using SPHERE at VLT, to further characterize its physical properties, and search for additional point sources in this young planetary system. Methods. We re-analyzed archival SPHERE NIR observations and obtained new data in Y, J, H and K spectral bands for a total of four different epochs. The data were reduced using the data reduction and handling pipeline and the SPHERE data center. We then applied custom routines (e.g., ANDROMEDA and PACO) to subtract the starlight. Results. We re-detect both PDS 70 b and c and confirm that PDS 70 c is gravitationally bound to the star. We estimate this second planet to be less massive than 5 MJup and with a Teff around 900 K. Also, it has a low gravity with logg between 3.0 and 3.5 dex. In addition, a third object has been identified at short separation (~0.12′′) from the star and gravitationally bound to the star. Its spectrum is however very blue, meaning that we are probably seeing stellar light reflected by dust and our analysis seems to demonstrate that it is a feature of the inner disk. We cannot however completely exclude the possibility that it is a planetary mass object enshrouded by a dust envelope. In this latter case, its mass should be of the order of a few tens of M⊕. Moreover, we propose a possible structure for the planetary system based on our data, and find that this structure cannot be stable on a long timescale.
Context. The study of high-contrast imaged brown dwarfs and exoplanets depends strongly on evolutionary models. To estimate the mass of a directly imaged substellar object, its extracted photometry ...or spectrum is used and adjusted with model spectra together with the estimated age of the system. These models still need to be properly tested and constrained. HD 4747B is a brown dwarf close to the H burning mass limit, orbiting a nearby (d = 19.25 ± 0.58 pc), solar-type star (G9V); it has been observed with the radial velocity method for over almost two decades. Its companion was also recently detected by direct imaging, allowing a complete study of this particular object. Aims. We aim to fully characterize HD 4747B by combining a well-constrained dynamical mass and a study of its observed spectral features in order to test evolutionary models for substellar objects and to characterize its atmosphere. Methods. We combined the radial velocity measurements of High Resolution Echelle Spectrometer (HIRES) and CORALIE taken over two decades and high-contrast imaging of several epochs from NACO, NIRC2, and SPHERE to obtain a dynamical mass. From the SPHERE data we obtained a low-resolution spectrum of the companion from Y to H band, and two narrow band-width photometric measurements in the K band. A study of the primary star also allowed us to constrain the age of the system and its distance. Results. Thanks to the new SPHERE epoch and NACO archival data combined with previous imaging data and high-precision radial velocity measurements, we were able to derive a well-constrained orbit. The high eccentricity (e = 0.7362 ± 0.0025) of HD 4747B is confirmed, and the inclination and the semi-major axis are derived (i = 47.3 ± 1.6°, a = 10.01 ± 0.21 au). We derive a dynamical mass of mB = 70.0 ± 1.6 MJup, which is higher than a previous study but in better agreement with the models. By comparing the object with known brown dwarfs spectra, we derive a spectral type of L9 and an effective temperature of 1350 ± 50 K. With a retrieval analysis we constrain the oxygen and carbon abundances and compare them with the values from the HR 8799 planets.
c-Myc promotes cell growth and transformation by ill-defined mechanisms. c-myc(-/-) mice die by embryonic day 10.5 (E10.5) with defects in growth and in cardiac and neural development. Here we report ...that the lethality of c-myc(-/-) embryos is also associated with profound defects in vasculogenesis and primitive erythropoiesis. Furthermore, c-myc(-/-) embryonic stem (ES) and yolk sac cells are compromised in their differentiative and growth potential. These defects are intrinsic to c-Myc, and are in part associated with a requirement for c-Myc for the expression of vascular endothelial growth factor (VEGF), as VEGF can partially rescue these defects. However, c-Myc is also required for the proper expression of other angiogenic factors in ES and yolk sac cells, including angiopoietin-2, and the angiogenic inhibitors thrombospondin-1 and angiopoietin-1. Finally, c-myc(-/-) ES cells are dramatically impaired in their ability to form tumors in immune-compromised mice, and the small tumors that sometimes develop are poorly vascularized. Therefore, c-Myc function is also necessary for the angiogenic switch that is indispensable for the progression and metastasis of tumors. These findings support the model wherein c-Myc promotes cell growth and transformation, as well as vascular and hematopoietic development, by functioning as a master regulator of angiogenic factors.
Context.
Detecting and characterizing substellar companions for which the luminosity, mass, and age can be determined independently is of utter importance to test and calibrate the evolutionary ...models due to uncertainties in their formation mechanisms. HD 19467 is a bright and nearby star hosting a cool brown dwarf companion detected with radial velocities and imaging, making it a valuable object for such studies.
Aims.
We aim to further characterize the orbital, spectral, and physical properties of the HD 19467 system.
Methods.
We present new high-contrast imaging data with the SPHERE and NaCo instruments. We also analyze archival data from the instruments HARPS, NaCo, HIRES, UVES, and ASAS. Furthermore, we use proper motion data of the star from H
IPPARCOS
and
Gaia
.
Results.
We refined the properties of the host star and derived an age of 8.0
+2.0
−1.0
Gyr based on isochrones, gyrochronology, and chemical and kinematic arguments. This age estimate is slightly younger than previous age estimates of ~9–11 Gyr based on isochrones. No orbital curvature is seen in the current imaging, radial velocity, and astrometric data. From a joint fit of the data, we refined the orbital parameters for HD 19467B, including: a period of 398
+95
−93
yr, an inclination of 129.8
+8.1
−5.1
deg, an eccentricity of 0.56 ± 0.09, a longitude of the ascending node of 134.8 ± 4.5 deg, and an argument of the periastron of 64.2
+5.5
−6.3
deg. We assess a dynamical mass of 74
+12
−9
M
J
. The fit with atmospheric models of the spectrophotometric data of the companion indicates an atmosphere without clouds or with very thin clouds, an effective temperature of 1042
+77
−71
K, and a high surface gravity of 5.34
+0.8
−0.9
dex. The comparison to model predictions of the bolometric luminosity and dynamical mass of HD 19467B, assuming our system age estimate, indicates a better agreement with the Burrows et al. (1997, ApJ, 491, 856) models; whereas, the other evolutionary models used tend to underestimate its cooling rate.
HD 95086 is an intermediate-mass debris-disk-bearing star. VLT/NaCo 3.8 μm observations revealed it hosts a 5 ± 2 MJup companion (HD 95086 b) at ≃56 AU. Follow-up observations at 1.66 and 2.18 μm ...yielded a null detection, suggesting extremely red colors for the planet and the need for deeper direct-imaging data. In this Letter, we report H-(1.7 μm) and K1-(2.05 μm) band detections of HD 95086 b from Gemini Planet Imager (GPI) commissioning observations taken by the GPI team. The planet position in both spectral channels is consistent with the NaCo measurements and we confirm it to be comoving. Our photometry yields colors of H − L′ = 3.6 ± 1.0 mag and K1 − L′ = 2.4 ± 0.7 mag, consistent with previously reported 5-σ upper limits in H and Ks. The photometry of HD 95086 b best matches that of 2M 1207 b and HR 8799 cde. Comparing its spectral energy distribution with the BT-SETTL and LESIA planet atmospheric models yields Teff ~ 600–1500 K and log g ~ 2.1–4.5. Hot-start evolutionary models yield M = 5 ± 2 MJup. Warm-start models reproduce the combined absolute fluxes of the object for M = 4–14 MJup for a wide range of plausible initial conditions (Sinit = 8–13 kB/baryon). The color−magnitude diagram location of HD 95086 b and its estimated Teff and log g suggest that the planet is a peculiar L − T transition object with an enhanced amount of photospheric dust.
Aims. HR 2562 is an F5V star located at ~33 pc from the Sun hosting a substellar companion that was discovered using the Gemini planet imager (GPI) instrument. The main objective of the present paper ...is to provide an extensive characterization of the substellar companion, by deriving its fundamental properties. Methods. We observed HR 2562 with the near-infrared branch composed by the integral field spectrograph (IFS) and the infrared dual band spectrograph (IRDIS) of the spectro-polarimetric high-contrast exoplanet research (SPHERE) instrument at the very large telescope (VLT). During our observations IFS was operating in the Y J band, while IRDIS was observing with the H broadband filter. The data were reduced with the dedicated SPHERE GTO pipeline, which is custom designed for this instrument. On the reduced images, we then applied the post-processing procedures that are specifically prepared to subtract the speckle noise. Results. The companion is clearly detected in both IRDIS and IFS datasets. We obtained photometry in three different spectral bands. The comparison with template spectra allowed us to derive a spectral type of T2–T3 for the companion. Using both evolutionary and atmospheric models we inferred the main physical parameters of the companion obtaining a mass of 32 ± 14 MJup, Teff = 1100 ± 200 K, and log g = 4.75 ± 0.41.
Context. Jets are rarely associated with pre-main sequence intermediate-mass stars. This contrasts with the frequent detection of jets in lower mass or younger stars. Optical and near-IR observations ...of jet-driving sources are often hindered by the presence of a natal envelope. Aims. Jets around partly embedded sources are a useful diagnostic to constrain the geometry of the concealed protoplanetary disk. We intend to clarify how the jet-driving mechanisms are affected by both spatial anisotropies and episodic variations at the (sub-)au scale from the star. Methods. We obtained a rich set of high-contrast VLT/SPHERE observations from 0.6 to 2.2 μm of the young intermediate-mass star RY Tau. Given the proximity to the Sun of this source, our images have the highest spatial resolution ever obtained for an atomic jet (down to ~4 au). Results. Optical observations in polarized light show no sign of the protoplanetary disk detected by ALMA. Instead, we observed a diffuse signal resembling a remnant envelope with an outflow cavity. The jet is detected in the Hα, S II at 1.03 μm, He I at 1.08 μm, and Fe II lines in the 1.25 μm and 1.64 μm. The jet appears to be wiggling and its radial width increasing with the distance is complementary to the shape of the outflow cavity suggesting a strong interaction with jet and envelope. Through the estimated tangential velocity (~100 km s−1), we revealed a possible connection between the launching time of the jet substructures and the stellar activity of RY Tau. Conclusions. RY Tau is at an intermediate stage toward the dispersal of the natal envelope. This source shows episodic increases of mass accretion and ejection similarly to other known intermediate-mass stars. The amount of observed jet wiggle is consistent with the presence of a precessing disk warp or misaligned inner disk that would be induced by an unseen planetary or sub-stellar companion at sub- or few-au scales respectively. The high disk mass of RY Tau and of two other jet-driving intermediate-mass stars, HD 163296 and MWC480, suggests that massive, full disks are more efficient at launching prominent jets.
Induction of the Arf tumor suppressor gene by elevated thresholds of mitogenic signals activates a p53-dependent transcriptional response that triggers either growth arrest or apoptosis, thereby ...countering abnormal cell proliferation. Conversely, Arf inactivation is associated with tumor development. Expression of Arf in tissues of adult mice is difficult to detect, possibly because its induction leads to the arrest or elimination of incipient tumor cells. We replaced coding sequences of exon 1β of the mouse cellular Arf gene with a cDNA encoding GFP, thereby producing Arf-null animals in which GFP expression is driven by the intact Arf promoter. The Arf promoter was induced in several biologic settings previously shown to elicit mouse p19Arfexpression. Inactivation of Arf in this manner led to the outgrowth of tumor cells expressing GFP, thereby providing direct evidence that the Arf promoter monitors latent oncogenic signals in vivo.
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