COVID-19 has been associated with negative results in patients with A blood group and with a better evolution in O blood group individuals.
Because the evidence regarding ABO blood groups and COVID ...was empirically not that clear in our country, we tested the association regarding COVID-19 and blood groups.
Adult patients were enrolled in this prospective, case-control, observational multicenter study. Patients with a confirmed diagnosis of COVID-19 were assigned to one of three groups based on the clinical presentation of the infection. Age, gender, ABO and Rh blood groups, body mass index, history of diabetes mellitus or high blood pressure, and smoking were recorded directly or from their clinical charts. ABO blood group was obtained from 5,000 blood donors (50% each gender). Atherothrombotic variables were compared with a nation-wide data collection.
A total of 2,416 patients with COVID-19 were included (women:39.6%; men:60.4%). There were no significant differences between cases and controls in terms of age. O blood group was the most frequently found in healthy donors and COVID-19 patients, but this blood group was significantly higher in COVID-19 patients vs. healthy donors. ABO blood group was not associated with the final health status in COVID-19 patients. Obesity, diabetes mellitus, hypertension and smoking were significantly more frequent among COVID-19 patients.
The proposed protective effect of the O blood group in COVID-19 patients could not be reproduced in the Mexican population while some atherothrombotic risk factors had a significant effect on the clinical evolution.
Abstract The aim of this study was to identify if the prevalence of dental pain (past and / or present) is associated with caries experience in Mexican children, as well as to characterize factors ...associated with dental pain. A cross-sectional study was conducted in a consecutive sample of 309 children 2 to 12 years old who were patients at a dental school clinic in Toluca, Mexico. Data were collected from clinical records. The dependent variable had three categories: 0 = have never had dental pain, 1 = had dental pain before the appointment, and 2 = current dental pain. Non-parametric statistical tests were used in the analysis. A multivariate multinomial logistic regression model was generated in Stata 11.0. Average age was 5.71 ± 2.43 years and 50.8% were boys. The joint dmft+DMFT index was 9.11 ± 4.19. It was observed that 56.6% of children did not report having experienced dental pain, 30.7% reported having previously had dental pain, and 12.6% had pain when the clinical appointment took place. In the multivariate model, variables associated (p < .05) with previous dental pain were age (OR = 1.13); the dmft + DMFT index (OR = 1.13), having had a last dental visit for curative/emergency reasons (OR = 2.41) and prior experience of dental trauma (OR = 2.59). For current pain, only the joint dmft + DMFT index (OR = 1.10, p < 0.05) had significant associations. Almost half of the children had experienced dental pain in their lifetime. Since caries experience is a factor associated with dental pain, decreasing caries levels may ameliorate suffering from dental pain in children.
Artisanal and small-scale gold-mining activities performed in mountain areas of the Southern Ecuadorian Amazon have incorporated several heavy metals into the aquatic systems, thus increasing the ...risk of exposure in populations living in adjacent zones. Therefore, the objective of this study was to evaluate the contamination levels of mercury (Hg) and manganese (Mn) in several rivers of the Nangaritza River basin and assess the exposure in school-aged children residing near the gold-mining zones. River water and sediment samples were collected from a highly contaminated (HE
x
) and a moderately contaminated (ME
x
) zones. Hair Mn (MnH) and urinary Hg (HgU) levels were determined in school-aged children living in both zones. High concentrations of dissolved Mn were found in river waters of the HE
x
zone (between 2660 and 3990 µg l
−1
); however, Hg levels, in general, were lower than the detection limit (DL; <1.0 µg l
−1
). Similarly, Mn levels in sediments were also increased (3090 to 4086 µg g
−1
). Median values of MnH in children of the HEx and MEx zones were 5.5 and 3.4 µg g
−1
, respectively, whereas the median values of HgU concentrations in children living in the HEx and MEx zones were 4.4 and 0.62 µg g-creat
−1
, respectively. Statistically significant differences were observed between both biomarkers in children from the HEx and MEx zones. In addition, boys presented significantly greater MnH levels in both zones. The greater MnH values were found in children living in alluvial areas, whereas children living in the high mountain areas, where some ore-processing plants are located close to or inside houses and schools, had the greater HgU concentrations. In summary, the data reported in this paper highlights that artisanal and small-scale gold-mining activities can not only produce mercurial contamination, that can also release other heavy metals (such as Mn) that may pose a risk to human health.
In order to place constraints on cosmology through optical surveys of galaxy clusters, one must first understand the properties of those clusters. To this end, we introduce the Mass Analysis Tool for ...Chandra (MATCha), a pipeline that uses a parallellized algorithm to analyze archival Chandra data. MATCha simultaneously calculates X-ray temperatures and luminosities and performs centering measurements for hundreds of potential galaxy clusters using archival X-ray exposures. We run MATCha on the redMaPPer SDSS DR8 cluster catalog and use MATCha's output X-ray temperatures and luminosities to analyze the galaxy cluster temperature-richness, luminosity-richness, luminosity-temperature, and temperature-luminosity scaling relations. We detect 447 clusters and determine 246 r2500 temperatures across all redshifts. Within 0.1 < z < 0.35, we find that r2500 TX scales with optical richness (λ) as with an intrinsic scatter of ( ). We investigate the distribution of offsets between the X-ray center and redMaPPer center within 0.1 < z < 0.35, finding that 68%.3 6.5% of clusters are well-centered. However, we find a broad tail of large offsets in this distribution, and we explore some of the causes of redMaPPer miscentering.
We perform the first blind analysis of cluster abundance data. Specifically, we derive cosmological constraints from the abundance and weak-lensing signal of \redmapper\ clusters of richness ...\(\lambda\geq 20\) in the redshift range \(z\in0.1,0.3\) as measured in the Sloan Digital Sky Survey (SDSS). We simultaneously fit for cosmological parameters and the richness--mass relation of the clusters. For a flat \(\Lambda\)CDM cosmological model with massive neutrinos, we find \(S_8 \equiv \sigma_{8}(\Omega_m/0.3)^{0.5}=0.79^{+0.05}_{-0.04}\). This value is both consistent and competitive with that derived from cluster catalogues selected in different wavelengths. Our result is also consistent with the combined probes analyses by the Dark Energy Survey (DES) and the Kilo-Degree Survey (KiDS), and with the Cosmic Microwave Background (CMB) anisotropies as measured by \planck. We demonstrate that the cosmological posteriors are robust against variation of the richness--mass relation model and to systematics associated with the calibration of the selection function. In combination with Baryon Acoustic Oscillation (BAO) data and Big-Bang Nucleosynthesis (BBN) data, we constrain the Hubble rate to be \(h=0.66\pm 0.02\), independent of the CMB. Future work aimed at improving our understanding of the scatter of the richness--mass relation has the potential to significantly improve the precision of our cosmological posteriors. The methods described in this work were developed for use in the forthcoming analysis of cluster abundances in the DES. Our SDSS analysis constitutes the first part of a staged-unblinding analysis of the full DES data set.
We present a direct measurement of the mean halo occupation distribution (HOD) of galaxies taken from the eleventh data release (DR11) of the Sloan Digital Sky Survey-III Baryon Oscillation ...Spectroscopic Survey (BOSS). The HOD of BOSS low-redshift (LOWZ: \(0.2 < z < 0.4\)) and Constant-Mass (CMASS: \(0.43 <z <0.7\)) galaxies is inferred via their association with the dark-matter halos of 174 X-ray-selected galaxy clusters drawn from the XMM Cluster Survey (XCS). Halo masses are determined for each galaxy cluster based on X-ray temperature measurements, and range between \({\rm log_{10}} (M_{180}/M_{\odot}) = 13-15\). Our directly measured HODs are consistent with the HOD-model fits inferred via the galaxy-clustering analyses of Parejko et al. for the BOSS LOWZ sample and White et al. for the BOSS CMASS sample. Under the simplifying assumption that the other parameters that describe the HOD hold the values measured by these authors, we have determined a best-fit alpha-index of 0.91\(\pm\)0.08 and \(1.27^{+0.03}_{-0.04}\) for the CMASS and LOWZ HOD, respectively. These alpha-index values are consistent with those measured by White et al. and Parejko et al. In summary, our study provides independent support for the HOD models assumed during the development of the BOSS mock-galaxy catalogues that have subsequently been used to derive BOSS cosmological constraints.
Autism and Paediatric Dentistry: A Scoping Review Herrera-Moncada, Mónica; Campos-Lara, Phenélope; Hernández-Cabanillas, Juan Carlos ...
Oral health & preventive dentistry,
2019, Volume:
17, Issue:
3
Journal Article
Peer reviewed
The objectives of this scoping review were: first, to pose a research question; second, to identify relevant studies to answer the research question; third, to select and retrieve the studies; ...fourth, to chart the critical data; and finally, to collate, summarise, and report the results from selected articles on the dental management of children affected with autism.
Relevant articles (randomised controlled trials, reviews, observational studies, and clinical case reports) published over an 11-year period were identified and retrieved from five internet databases: PubMed, Embase/Ovid, Cochrane Library, Google Scholar, and EBSCO.
By title and abstract screening and after removing duplicates, 25 articles were finally included in the present scoping review. According to the extracted data, the following four clinical issues were found to be most important: patient behavioural control, prevalence/incidence of dental caries, adverse effects and interactions with medications, and orthodontic management. Additionally, several useful clinical recommendations are provided.
Paediatric dentists should bear in mind that early diagnosis and treatment, effective communication skills, and a long-term follow-up of children with autism continue to be the best approaches for achieving enhanced patient psychological well-being and consequently a better quality of life.
Key Clinical Message
The evaluation of first‐degree family members is very important to detect additional cases of polyglandular autoimmune syndrome type 2. The genetic evaluation of human leukocyte ...antigen (HLA) may be useful in the study of this syndrome. This study is the first report of an HLA study of this syndrome in a Mexican family.
The evaluation of first‐degree family members is very important to detect additional cases of polyglandular autoimmune syndrome type 2. The genetic evaluation of human leukocyte antigen (HLA) may be useful in the study of this syndrome. This study is the first report of an HLA study of this syndrome in a Mexican family.
We describe updates to the \redmapper{} algorithm, a photometric red-sequence cluster finder specifically designed for large photometric surveys. The updated algorithm is applied to ...\(150\,\mathrm{deg}^2\) of Science Verification (SV) data from the Dark Energy Survey (DES), and to the Sloan Digital Sky Survey (SDSS) DR8 photometric data set. The DES SV catalog is locally volume limited, and contains 786 clusters with richness \(\lambda>20\) (roughly equivalent to \(M_{\rm{500c}}\gtrsim10^{14}\,h_{70}^{-1}\,M_{\odot}\)) and \(0.2<z<0.9\). The DR8 catalog consists of 26311 clusters with \(0.08<z<0.6\), with a sharply increasing richness threshold as a function of redshift for \(z\gtrsim 0.35\). The photometric redshift performance of both catalogs is shown to be excellent, with photometric redshift uncertainties controlled at the \(\sigma_z/(1+z)\sim 0.01\) level for \(z\lesssim0.7\), rising to \(\sim0.02\) at \(z\sim0.9\) in DES SV. We make use of \emph{Chandra} and \emph{XMM} X-ray and South Pole Telescope Sunyaev-Zeldovich data to show that the centering performance and mass--richness scatter are consistent with expectations based on prior runs of \redmapper{} on SDSS data. We also show how the \redmapper{} \photoz{} and richness estimates are relatively insensitive to imperfect star/galaxy separation and small-scale star masks.
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