Summary
Background
We observed that minute amounts of thrombin or the enzyme Russell's viper venom activating factor V (RVV‐V) added to plasma strongly diminish the potential of that plasma to ...generate thrombin after being triggered by tissue factor.
Objective
To find the mechanism behind this phenomenon.
Methods and Results
Thrombin generation (TG) initiated by tissue factor (TF) is strongly and dose‐dependently inhibited by addition of activated factor V (FVa) or by addition of a factor V activator (thrombin or RVV‐V). No inhibition is seen when TG is triggered via the intrinsic pathway or by direct activation of factor X. The effect is independent of proteins C and S and tissue factor pathway inhibitor (TFPI). In factor VII‐deficient plasma the effect is seen when it is spiked with recombinant factor VII (FVII) and to a much lesser extent when spiked with recombinant FVIIa. In a purified system, FVa also dose‐dependently inhibits the activation of FX by TF/FVII(a). The inhibitory effect is neutralized by antibodies against the light chain of FVa but not by antibodies against the heavy chain.
Conclusions
Our observations can be explained by assuming that FVa, via its light chain, binds to the complex TF/FVII(a) and prevents it from activating FX. We assume that this mechanism reduces the possibility that thrombin and factor Xa escaping from a wound area into the circulation, together with blood‐borne tissue factor, would trigger intravascular coagulation.
We report a new subdwarf B pulsator, PG 1142-037, discovered during the first full-length campaign of K2, the two-gyro mission of the Kepler space telescope. 14 periodicities have been detected ...between 0.9 and 2.5 hr with amplitudes below 0.35 parts-per-thousand. We have been able to associate all of the pulsations with low-degree, ℓ ≤ 2 modes. Follow-up spectroscopy of PG 1142 has revealed it to be in a binary with a period of 0.54 d. Phase-folding the K2 photometry reveals a two-component variation including both Doppler boosting and ellipsoidal deformation. Perhaps the most surprising and interesting result is the detection of an ellipsoidal, tidally distorted variable with no indication of rotationally induced pulsation multiplets. This indicates that the rotation period is longer than 45 d, even though the binary period is near 13 h.
2M1938+4603 (KIC 9472174) displays a spectacular light curve dominated by a strong reflection effect and rather shallow, grazing eclipses. The orbital period is 0.126 d, the second longest period yet ...found for an eclipsing sdB+dM, but still close to the minimum 0.1-d period among such systems. The phase-folded Kepler light curve was used to detrend the orbital effects from the data set. The amplitude spectrum of the residual light curve reveals a rich collection of pulsation peaks spanning frequencies from ∼50 to 4500 μHz. The presence of a complex pulsation spectrum in both the p- and g-mode regions has never before been reported in a compact pulsator. Eclipsing sdB+dM stars are very rare, with only seven systems known and only one with a pulsating primary. Pulsating stars in eclipsing binaries are especially important since they permit masses derived from seismological model fits to be cross-checked with orbital mass constraints. We present a first analysis of this star based on the Kepler 9.7-d commissioning light curve and extensive ground-based photometry and spectroscopy that allow us to set useful bounds on the system parameters. We derive a radial-velocity amplitude K1 = 65.7 ± 0.6 km s −1, inclination angle , and find that the masses of the components are M1 = 0.48 ± 0.03 M⊙ and M2 = 0.12 ± 0.01 M⊙.
We present a light-curve analysis and radial velocity study of KOI-74, an eclipsing A star + white dwarf binary with a 5.2-d orbit. Aside from new spectroscopy covering the orbit of the system, we ...used 212 d of publicly available Kepler observations and present the first complete light-curve fitting to these data, modelling the eclipses and transits, ellipsoidal modulation, reflection and Doppler beaming. Markov chain Monte Carlo simulations are used to determine the system parameters and uncertainty estimates. Our results are in agreement with earlier studies, except that we find an inclination of 87°.0 ± 0°.4, which is significantly lower than the previously published value. The altered inclination leads to different values for the relative radii of the two stars and therefore also the mass ratio deduced from the ellipsoidal modulations seen in this system. We find that the mass ratio derived from the radial velocity amplitude (q= 0.104 ± 0.004) disagrees with that derived from the ellipsoidal modulation (q= 0.052 ± 0.004 assuming corotation). This was found before, but with our smaller inclination, the discrepancy is even larger than previously reported. Accounting for the rapid rotation of the A-star, instead of assuming corotation with the binary orbit, is found to increase the discrepancy even further by lowering the mass ratio to q= 0.047 ± 0.004. These results indicate that one has to be extremely careful in using the amplitude of an ellipsoidal modulation signal in a close binary to determine the mass ratio, when a proof of corotation is not firmly established. The same problem could arise whenever an ellipsoidal modulation amplitude is used to derive the mass of a planet orbiting a host star that is not in corotation with the planet's orbit.
The radial velocities that can be inferred from the detected Doppler beaming in the light curve are found to be in agreement with our spectroscopic radial velocity determination. We also report the first measurement of Rømer delay in a light curve of a compact binary. This delay amounts to −56 ± 17 s and is consistent with the mass ratio derived from the radial velocity amplitude. The firm establishment of this mass ratio at q= 0.104 ± 0.004 leaves little doubt that the companion of KOI-74 is a low-mass white dwarf.
ABSTRACT
We present phase-resolved spectroscopy, photometry, and circular spectropolarimetry of the eclipsing polar UZ Fornacis. Doppler tomography of the strongest emission lines using the ...inside-out projection revealed the presence of three emission regions: from the irradiated face of the secondary star, the ballistic stream and the threading region, and the magnetically confined accretion stream. The total intensity spectrum shows broad emission features and a continuum that rises in the blue. The circularly polarized spectrum shows the presence of three cyclotron emission harmonics at ∼4500, 6000, and 7700 Å, corresponding to harmonic numbers 4, 3, and 2, respectively. These features are dominant before the eclipse and disappear after the eclipse. The harmonics are consistent with a magnetic field strength of ∼57 MG. We also present phase-resolved circular and linear photopolarimetry to complement the spectropolarimetry around the times of eclipse. MeerKAT radio observations show a faint source that has a peak flux density of 30.7 ± 5.4 $\mu$Jy beam−1 at 1.28 GHz at the position of UZ For.
Abstract
We report the discovery and analysis of PTF1 J085713+331843, a new eclipsing post-common-envelope detached white-dwarf–red-dwarf binary with a 2.5 h orbital period discovered by the Palomar ...Transient Factory. ULTRACAM multicolour photometry over multiple orbital periods reveals a light curve with a deep flat-bottomed primary eclipse and a strong reflection effect. Phase-resolved spectroscopy shows broad Balmer absorption lines from the DA white dwarf and phase-dependent Balmer emission lines originating on the irradiated side of the red dwarf. The temperature of the DA white dwarf is T
WD = 25 700 ± 400 K and the spectral type of the red dwarf is M3–M5. A combined modelling of the light curve and the radial velocity variations results in a white dwarf mass of
$M_\mathrm{WD} = 0.61^{+0.18}_{-0.17}\, \mathrm{M_{{\odot }}}$
and radius of
$R_\mathrm{WD} = 0.0175^{+0.0012}_{-0.0011}\, \mathrm{R_{{\odot }}}$
, and a red dwarf mass and radius of
$M_\mathrm{RD} = 0.19^{+0.10}_{-0.08}\, \mathrm{M_{{\odot }}}$
and
$R_\mathrm{RD} = 0.24^{+0.04}_{-0.04}\, \mathrm{R_{{\odot }}}$
. The system is either a detached cataclysmic variable or has emerged like from the common-envelope phase at nearly its current orbital period. In
${\sim }70$
Myr, this system will become a cataclysmic variable in the period gap.
We present results from the final 6 months of a survey to search for pulsations in white dwarfs (WDs) and hot subdwarf stars with the Kepler spacecraft. Spectroscopic observations are used to ...separate the objects into accurate classes, and we explore the physical parameters of the subdwarf B (sdB) stars and white dwarfs in the sample. From the Kepler photometry and our spectroscopic data, we find that the sample contains five new pulsators of the V1093 Her type, one AM CVn type cataclysmic variable and a number of other binary systems.
This completes the survey for compact pulsators with Kepler. No V361 Hya type of short-period pulsating sdB stars were found in this half, leaving us with a total of one single multiperiodic V361 Hya and 13 V1093 Her pulsators for the full survey. Except for the sdB pulsators, no other clearly pulsating hot subdwarfs or white dwarfs were found, although a few low-amplitude candidates still remain. The most interesting targets discovered in this survey will be observed throughout the remainder of the Kepler mission, providing the most long-term photometric data sets ever made on such compact, evolved stars. Asteroseismic investigations of these data sets will be invaluable in revealing the interior structure of these stars and will boost our understanding of their evolutionary history.
We report on extended photometry of two pulsating subdwarf B (sdB) stars in close binaries. For both cases, we use rotational splitting of the pulsation frequencies to show that the sdB component ...rotates much too slowly to be in synchronous rotation. We use a theory of tidal interaction in binary stars to place limits on the mass ratios that are independent of estimates based on the radial velocity curves. The companions have masses below 0.26 M⊙. The pulsation spectra show the signature of high-overtone g-mode pulsation. One star, KIC 11179657, has a clear sequence of g modes with equal period spacings as well as several periodicities that depart from that trend. KIC 02991403 shows a similar sequence, but has many more modes that do not fit the simple pattern.
The survey phase of the Kepler Mission includes a number of hot subdwarf B (sdB) stars to search for non-radial pulsations. We present our analysis of two sdB stars that are found to be g-mode ...pulsators of the V1093 Her class. These two stars also display the distinct irradiation effect typical of sdB stars with a close M-dwarf companion with orbital periods of less than half a day. Because the orbital period is so short, the stars should be in synchronous rotation, and if so, the rotation period should imprint itself on the multiplet structure of the pulsations. However, we do not find clear evidence for such rotational splitting. Though the stars do show some frequency spacings that are consistent with synchronous rotation, they also display multiplets with splittings that are much smaller. Longer-duration time series photometry will be needed to determine if those small splittings are in fact rotational splitting, or caused by slow amplitude or phase modulation. Further data should also improve the signal-to-noise ratio, perhaps revealing lower-amplitude periodicities that could confirm the expectation of synchronous rotation. The pulsation periods seen in these stars show period spacings that are suggestive of high-overtone g-mode pulsations.
The project Massive Unseen Companions to Hot Faint Underluminous Stars from SDSS (MUCHFUSS) aims to discover subdwarf-B stars with massive compact companions such as overmassive white dwarfs (M > 1.0 ...M sub(middot in circle)), neutron stars or black holes. From the 127 subdwarfs with substantial radial-velocity variations discovered in the initial survey, a number of interesting objects have been selected for extensive follow-up. After an initial photometry run with BUSCA revealed that FBS 0117+396 is photometrically variable both on long and short timescales, we chose it as an auxiliary target during a 6-night multi-color photometry run with Ultracam. Spectroscopy was obtained at a number of observatories in order to determine the binary period and obtain a radial-velocity amplitude. After establishing an orbital period of P = 0.252 d, and removing the signal associated with the irradiated hemisphere of the M-dwarf companion, we were able to detect ten pulsation periods in the Fourier spectrum of the light curve. Two pulsation modes are found to have short periods of 337 and 379 s, and at least eight modes are found with periods between 45 min and 2.5 h. This establishes that FBS 0117+396 is an sdB+dM reflection binary, in which the primary is a hybrid pulsator, and the first one found with this particular melange of flavours.
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