Summary
Peanut nut and tree nut allergy are characterised by IgE mediated reactions to nut proteins. Nut allergy is a global disease. Limited epidemiological data suggest varying prevalence in ...different geographical areas. Primary nut allergy affects over 2% of children and 0.5% of adults in the UK. Infants with severe eczema and/or egg allergy have a higher risk of peanut allergy. Primary nut allergy presents most commonly in the first five years of life, often after the first known ingestion with typical rapid onset IgE‐mediated symptoms. The clinical diagnosis of primary nut allergy can be made by the combination of a typical clinical presentation and evidence of nut specifc IgE shown by a positive skin prick test (SPT) or specific IgE (sIgE) test. Pollen food syndrome is a distinct disorder, usually mild, with oral/pharyngeal symptoms, in the context of hay fever or pollen sensitisation, which can be triggered by nuts. It can usually be distinguish clinically from primary nut allergy. The magnitude of a SPT or sIgE relates to the probability of clinical allergy, but does not relate to clinical severity. SPT of ≥ 8 mm or sIgE ≥ 15 KU/L to peanut is highly predictive of clinical allergy. Cut off values are not available for tree nuts. Test results must be interpreted in the context of the clinical history. Diagnostic food challenges are usually not necessary but may be used to confirm or refute a conflicting history and test result. As nut allergy is likely to be a long‐lived disease, nut avoidance advice is the cornerstone of management. Patients should be provided with a comprehensive management plan including avoidance advice, patient specific emergency medication and an emergency treatment plan and training in administration of emergency medication. Regular re‐training is required.
The body-positive movement is one of many decentralized, user-generated movements on social media that seek to engender positive societal change. In support of the body-positive movement, social ...media users employ a variety of messages and images to advocate for more inclusive beauty standards across different online platforms. We examine how the nature of body-positive messaging (mainstream body positivity vs body neutrality), the degree to which images are sexualized (sexualized vs non-sexualized), and the platform that hosts body-positive content (Instagram/Flickr/blog) influence how people evaluate body-positive content online. The results indicate that the more participants felt messaging was body-neutral, the more morally appropriate and less self-interested they found the posts. The extent to which participants felt messaging was morally appropriate also led them to embrace more inclusive beauty standards. Moreover, non-sexualized (vs sexualized) images were rated more morally appropriate and less self-interested. Implications for promoting body positivity and other prosocial movements online are discussed.
Here, we verify the depigmenting action of Pouteria macrophylla fruit extract (EXT), incorporate it into a safe topical microemulsion and assess its effectiveness in a 3D pigmented skin model. ...Melanocytes-B16F10- were used to assess the EXT effects on cell viability, melanin synthesis, and melanin synthesis-related gene transcription factor expression, which demonstrated a 32% and 50% reduction of intra and extracellular melanin content, respectively. The developed microemulsion was composed of Cremophor EL®/Span 80 4:1 (w/w), ethyl oleate, and pH 4.5 HEPES buffer and had an average droplet size of 40 nm (PdI 0.40 ± 0.07). Skin irritation test with reconstituted epidermis (Skin Ethic RHETM) showed that the formulation is non-irritating. Tyrosinase inhibition was maintained after skin permeation in vitro, in which microemulsion showed twice the inhibition of the conventional emulsion (20.7 ± 2.2% and 10.7 ± 2.4%, respectively). The depigmenting effect of the microemulsion was finally confirmed in a 3D culture model of pigmented skin, in which histological analysis showed a more pronounced effect than a commercial depigmenting formulation. In conclusion, the developed microemulsion is a promising safe formulation for the administration of cutite fruit extract, which showed remarkable depigmenting potential compared to a commercial formulation.
Proponents of the body positivity (BoPo) movement prominently use social media to promote body appreciation and normalize marginalized bodies. However, companies and social media users have ...increasingly commodified the movement for self-serving reasons or economic gain. Providing a unique test of the persuasion knowledge model, this experiment examined (a) how the commodification of a prosocial movement can undermine its efficacy and (b) how the symmetry between visual and text-based messaging can influence viewer reactions. Results indicated that body positive posts on Instagram that contained self-promotion or promoted products were viewed as less morally appropriate and were less effective at promoting body appreciation and inclusivity. Practical implications are discussed and a novel boundary condition for the persuasion knowledge model is presented.
Summary
This guideline advises on the management of patients with egg allergy. Most commonly, egg allergy presents in infancy, with a prevalence of approximately 2% in children and 0.1% in adults. A ...clear clinical history and the detection of egg white‐specific IgE (by skin prick test or serum assay) will confirm the diagnosis in most cases. Egg avoidance advice is the cornerstone of management. Egg allergy often resolves and re‐introduction can be achieved at home if reactions have been mild and there is no asthma. Patients with a history of severe reactions or asthma should have reintroduction guided by a specialist. All children with egg allergy should receive measles, mumps and rubella (MMR) vaccination. Influenza and yellow fever vaccines should only be considered in egg‐allergic patients under the guidance of an allergy specialist. This guideline was prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and Clinical Immunology (BSACI) and is intended for allergists and others with a special interest in allergy. The recommendations are evidence‐based but where evidence was lacking consensus was reached by the panel of specialists on the committee. The document encompasses epidemiology, risk factors, diagnosis, treatment, prognosis and co‐morbid associations.
Cite this as: A. T. Clark, I. Skypala, S. C. Leech, P. W. Ewan, P. Dugué, N. Brathwaite, P. A. J. Huber and S. M. Nasser, Clinical & Experimental Allergy, 2010 (40) 1116–1129.
•Body-positive images shared on social media can enhance positive body image.•We experimentally document how the beneficial effects of these images can be diminished.•Sexualized images led to more ...support of traditional beauty ideals and self-serving reasons.•Sexualized images also instigated other-objectification.•Images thought to be digitally modified were less effective and more negatively evaluated.
The body positive movement on social media seeks to challenge narrow conceptualizations of beauty that media outlets traditionally perpetuate and reinforce. Through a 2 × 2 between-subjects online experiment, we examined how the nature and authenticity of body-positive imagery on social media affects female viewers and their evaluations of body-positive content (N = 425, Mage = 35.47, SDage = 13.52). Specifically, participants viewed and reacted to a series of 10 body-positive images of women on social media varying in their degree of sexualization (sexualized vs. non-sexualized) and evidence of digital photo modifications (modification icons vs. no modification icons). A control group that featured landscape images was also included. Results indicate body-positive images that are considered sexualized and are believed to be digitally modified can undercut the movement’s intended aims: Participants who viewed body-positive images that were sexualized (vs. non-sexualized) and included photo modification icons (vs. no modification icons) reported greater endorsement of traditional beauty ideals (e.g., thinness) and thought the images were shared for self-serving reasons (e.g., to gain likes/shares/endorsements); these relationships were mediated by the extent to which viewers believed these images were sexualized and digitally modified. Further, results indicate that sexualized body-positive images can instigate sexual objectification of others and oneself. Those who viewed control images (vs. experimental body-positive images) produced significantly fewer sexually objectifying words about others and themselves. Implications for both viewers and producers (e.g., individuals, corporations) of body-positive imagery on social media are discussed in light of objectification theory.
Our work adopted an intersectional approach to investigate how women’s racial identity may influence how they evaluate and are impacted by body-positive imagery of women on social media. In a 2 × 2 × ...2 experiment (N = 975), we examined how source race (Black vs White) and sexualization (non-sexualized vs sexualized) in body-positive images affect Black and White viewers’ impressions of self-interest, moral appropriateness, and body positivity. Results indicated that viewers generally responded more favorably to non-sexualized (vs sexualized) images: Participants reported less self-interested motivations for sharing, found the images more morally appropriate, and believed they were more effective representations of body positivity. Results also revealed that Black (vs White) viewers tended to express more appreciation for body-positive imagery, regardless of source race or sexualization. Findings not only advance our theoretical understanding of sexual objectification with more diverse depictions and broader sampling, but also provide practical suggestions for advocates of the body-positive movement.
To determine the socio-economic determinants of obesity in adults in The Bahamas.
A subpopulation of adults 21 to 60 years was analysed for socio-economic differences in obesity levels. Data from the ...2001 Bahamas Living Conditions Survey, a nationwide comprehensive household survey which included anthropometric measurements, were used. Bivariate and binary logistic regression methods for complex samples were employed.
Overall obesity prevalence was 32% (38% female, 25% male, p = < 0.0001). An inverse relationship by education appeared to be the strongest predictor for all persons (OR = 0.78, CI 0.67, 0.90; p < 0.0001). This relationship was also evident for females (OR = 0.71, CI 0.59, 0.85; p < 0.0001) while a positive relationship existed by economic level for males (OR = 1.23, CI 1.07, 1.41; p = 0.005). There was a difference in food group expenditure for starchy vegetables only (p = 0.049). Other food group household expenditure, urban residence and female headed households showed no significant differences by obesity.
In line with international trends, obesity rates are high in The Bahamas, and especially affect females of lower socio-economic status. Public policy that targets this group is necessary to address this health concern.
Data are lacking on long-term effects of HIV behavioural intervention programmes. In this study, we report intervention effects 36 months postintervention on condom use and relevant outcome variables ...from the theory-based programme 'Focus on Youth in the Caribbean' (FOYC). Participants (1360 sixth-grade youth) were randomized by school into: (1) FOYC, plus one of two brief parent interventions or (2) the control condition 'Wondrous Wetlands', plus a brief parent intervention. Mixed effect analysis demonstrated significant programme effects, including enhanced HIV/AIDS knowledge (effect size D = 0.44, 95% confidence interval CI: 0.43, 0.46), increased self-efficacy of (D = 0.42, 95% CI: 0.30, 0.54), skills for (D = 0.62, 95% CI: 0.56, 0.64) and intention to use a condom (D = 0.20, 95% CI: 0.03, 0.37). Youth who received FOYC plus the parental monitoring intervention had higher condom use rates (odds ratio = 1.49, 95% CI: 0.97, 2.28). Feedback effects from key variables were also detected, supporting the sustained effect.
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