The aim of the SYRMA-CT collaboration is to set-up the first clinical trial of phase-contrast breast CT with synchrotron radiation (SR). In order to combine high image quality and low delivered dose ...a number of innovative elements are merged: a CdTe single photon counting detector, state-of-the-art CT reconstruction and phase retrieval algorithms. To facilitate an accurate exam optimization, a Monte Carlo model was developed for dose calculation using GEANT4. In this study, high isotropic spatial resolution (120 μm)(3) CT scans of objects with dimensions and attenuation similar to a human breast were acquired, delivering mean glandular doses in the range of those delivered in clinical breast CT (5-25 mGy). Due to the spatial coherence of the SR beam and the long distance between sample and detector, the images contain, not only absorption, but also phase information from the samples. The application of a phase-retrieval procedure increases the contrast-to-noise ratio of the tomographic images, while the contrast remains almost constant. After applying the simultaneous algebraic reconstruction technique to low-dose phase-retrieved data sets (about 5 mGy) with a reduced number of projections, the spatial resolution was found to be equal to filtered back projection utilizing a four fold higher dose, while the contrast-to-noise ratio was reduced by 30%. These first results indicate the feasibility of clinical breast CT with SR.
Assembly and test of the gas pixel detector for X-ray polarimetry Li, H.; Feng, H.; Muleri, F. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
12/2015, Volume:
804
Journal Article
Peer reviewed
Open access
The gas pixel detector (GPD) dedicated for photoelectric X-ray polarimetry is selected as the focal plane detector for the ESA medium-class mission concept X-ray Imaging and Polarimetry Explorer ...(XIPE). Here we show the design, assembly, and preliminary test results of a small GPD for the purpose of gas mixture optimization needed for the phase A study of XIPE. The detector is assembled in house at Tsinghua University following a design by the INFN-Pisa group. The improved detector design results in a good uniformity for the electric field. Filled with pure dimethyl ether (DME) at 0.8atm, the measured energy resolution is 18% at 6keV and inversely scales with the square root of the X-ray energy. The measured modulation factor is well consistent with that from simulation, up to ~0.6 above 6keV. The residual modulation is found to be 0.30±0.15% at 6keV for the whole sensitive area, which can be translated into a systematic error of less than 1% for polarization measurement at a confidence level of 99%. The position resolution of the detector is about 80μm in FWHM, consistent with previous studies and sufficient for XIPE requirements.
X-rays are particularly suited to probing the physics of extreme objects. However, despite the enormous improvements of X-ray astronomy in imaging, spectroscopy, and timing, polarimetry remains ...largely unexplored. We propose the photoelectric polarimeter Gas Pixel Detector (GPD) as a candidate instrument to fill the gap created by more than 30 yr without measurements. The GPD, in the focus of a telescope, will increase the sensitivity of orders of magnitude. Moreover, since it can measure the energy, the position, the arrival time, and the polarization angle of every single photon, it allows us to perform polarimetry of subsets of data singled out from the spectrum, the light curve, or an image of the source. The GPD has an intrinsic, very fine imaging capability, and in this work we report on the calibration campaign carried out in 2012 at the PANTER X-ray testing facility of the Max-Planck-Institut fur extraterrestrische Physik of Garching (Germany) in which, for the first time, we coupled it with a JET-X optics module with a focal length of 3.5 m and an angular resolution of 18 arc sec at 4.5 keV. This configuration was proposed in 2012 aboard the X-ray Imaging Polarimetry Explorer (XIPE) in response to the ESA call for a small mission. We derived the imaging and polarimetric performance for extended sources like pulsar wind nebulae and supernova remnants as case studies for the XIPE configuration and also discuss possible improvements by coupling the detector with advanced optics that have a finer angular resolution and larger effective areas to study extended objects with more detail.
The Gas Pixel Detector belongs to the very limited class of gas detectors optimized for the measurement of X-ray polarization in the emission of astrophysical sources. The choice of the mixture in ...which X-ray photons are absorbed and photoelectrons propagate, deeply affects both the energy range of the instrument and its performance in terms of gain, track dimension and ultimately, polarimetric sensitivity. Here we present the characterization of the Gas Pixel Detector with a 1
cm thick cell filled with dimethyl ether (DME) at 0.79
atm, selected among other mixtures for the very low diffusion coefficient. Almost completely polarized and monochromatic photons were produced at the calibration facility built at INAF/IASF-Rome exploiting Bragg diffraction at nearly 45°. For the first time ever, we measured the modulation factor and the spectral capabilities of the instrument at energies as low as 2.0
keV, but also at 2.6, 3.7, 4.0, 5.2 and 7.8
keV. These measurements cover almost completely the energy range of the instrument and allows to compare the sensitivity achieved with that of the standard mixture, composed of helium and DME.
The Tracker subsystem of the Large Area Telescope (LAT) science instrument of the Gamma-ray Large Area Space Telescope (GLAST) mission has been completed and tested. It is the central detector ...subsystem of the LAT and serves both to convert an incident gamma-ray into an electron–positron pair and to track the pair in order to measure the gamma-ray direction. It also provides the principal trigger for the LAT. The Tracker uses silicon strip detectors, read out by custom electronics, to detect charged particles. The detectors and electronics are packaged, along with tungsten converter foils, in 16 modular, high-precision carbon-composite structures. It is the largest silicon-strip detector system ever built for launch into space, and its aggressive design emphasizes very low power consumption, passive cooling, low noise, high efficiency, minimal dead area, and a structure that is highly transparent to charged particles. The test program has demonstrated that the system meets or surpasses all of its performance specifications as well as environmental requirements. It is now installed in the completed LAT, which is being prepared for launch in early 2008.
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