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  • Evolution pathways of IgE r... Evolution pathways of IgE responses to grass and mite allergens throughout childhood
    Custovic, Adnan, MD, PhD; Sonntag, Hans-Joachim, MRes; Buchan, Iain E., MD, PhD ... Journal of allergy and clinical immunology, 12/2015, Volume: 136, Issue: 6
    Journal Article
    Peer reviewed
    Open access

    Background Little is known about longitudinal patterns of the development of IgE to distinct allergen components. Objective We sought to investigate the evolution of IgE responses to allergenic ...
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  • Assessing life-space mobili... Assessing life-space mobility for a more holistic view on wellbeing in geriatric research and clinical practice
    Taylor, Joanne K.; Buchan, Iain E.; van der Veer, Sabine N. Aging clinical and experimental research, 04/2019, Volume: 31, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Life-space mobility (LSM) is a holistic measure of resilience to physical decline and social isolation in later life. To promote its use as an outcome in geriatric studies and in clinical practice, ...
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  • Collider Bias Is Only a Par... Collider Bias Is Only a Partial Explanation for the Obesity Paradox
    Sperrin, Matthew; Candlish, Jane; Badrick, Ellena ... Epidemiology, 2016-July, Volume: 27, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    BACKGROUND:“Obesity paradox” refers to an association between obesity and reduced mortality (contrary to an expected increased mortality). A common explanation is collider stratification ...
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  • Long-term Glycemic Variability and Risk of Adverse Outcomes: A Systematic Review and Meta-analysis
    Gorst, Catherine; Kwok, Chun Shing; Aslam, Saadia ... Diabetes care, 12/2015, Volume: 38, Issue: 12
    Journal Article
    Peer reviewed
    Open access

    Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c ...
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  • Outcome-sensitive multiple ... Outcome-sensitive multiple imputation: a simulation study
    Kontopantelis, Evangelos; White, Ian R; Sperrin, Matthew ... BMC medical research methodology, 01/2017, Volume: 17, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Multiple imputation is frequently used to deal with missing data in healthcare research. Although it is known that the outcome should be included in the imputation model when imputing missing ...
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  • Trajectories of lung function during childhood
    Belgrave, Danielle C M; Buchan, Iain; Bishop, Christopher ... American journal of respiratory and critical care medicine, 05/2014, Volume: 189, Issue: 9
    Journal Article
    Peer reviewed
    Open access

    Developmental patterns of lung function during childhood may have major implications for our understanding of the pathogenesis of respiratory disease throughout life. To explore longitudinal ...
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  • Lung function trajectories ... Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies
    Belgrave, Danielle C M; Granell, Raquel; Turner, Steve W ... The lancet respiratory medicine, 07/2018, Volume: 6, Issue: 7
    Journal Article
    Peer reviewed
    Open access

    Maximal lung function in early adulthood is an important determinant of mortality and COPD. We investigated whether distinct trajectories of lung function are present during childhood and whether ...
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