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hits: 41
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  • Synthesis, conformational a... Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment
    Bermejo, Iris A; Navo, Claudio D; Castro-López, Jorge ... Chemical science, 03/2020, Volume: 11, Issue: 15
    Journal Article
    Peer reviewed
    Open access

    The Tn antigen (GalNAc-α-1-O-Thr/Ser) is a well-known tumor-associated carbohydrate determinant. The use of glycopeptides that incorporate this structure has become a significant and promising niche ...
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  • Tn Antigen Mimics Based on sp(2)-Iminosugars with Affinity for an anti-MUC1 Antibody
    Fernández, Elena M Sánchez; Navo, Claudio D; Martínez-Sáez, Nuria ... Organic letters, 08/2016, Volume: 18, Issue: 15
    Journal Article
    Peer reviewed

    The first examples of amino acid (Ser/Thr)-sp(2)-iminosugar glycomimetic conjugates featuring an α-O-linked pseudoanomeric linkage are reported. The key synthetic step involves the completely ...
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  • Tn Antigen Mimics Based on ... Tn Antigen Mimics Based on sp 2‑Iminosugars with Affinity for an anti-MUC1 Antibody
    Fernández, Elena M. Sánchez; Navo, Claudio D; Martínez-Sáez, Nuria ... Organic letters, 08/2016, Volume: 18, Issue: 15
    Journal Article
    Peer reviewed

    The first examples of amino acid (Ser/Thr)–sp 2-iminosugar glycomimetic conjugates featuring an α-O-linked pseudoanomeric linkage are reported. The key synthetic step involves the completely ...
Full text
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  • A leaky mutation in CD3D di... A leaky mutation in CD3D differentially affects αβ and γδ T cells and leads to a Tαβ-Tγδ+B+NK+ human SCID
    Gil, Juana; Busto, Elena M; Garcillán, Beatriz ... The Journal of clinical investigation, 10/2011, Volume: 121, Issue: 10
    Journal Article
    Peer reviewed
    Open access

    T cells recognize antigens via their cell surface TCR and are classified as either αβ or γδ depending on the variable chains in their TCR, α and β or γ and δ, respectively. Both αβ and γδ TCRs also ...
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6.
  • Synthesis, conformational a... Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp 2 -iminosugar fragment
    Bermejo, Iris A.; Navo, Claudio D.; Castro-López, Jorge ... Chemical science (Cambridge), 04/2020, Volume: 11, Issue: 15
    Journal Article
    Peer reviewed

    The Tn antigen (GalNAc-α-1- O -Thr/Ser) is a well-known tumor-associated carbohydrate determinant. The use of glycopeptides that incorporate this structure has become a significant and promising ...
Full text

PDF
7.
  • CD3γ-independent pathways i... CD3γ-independent pathways in TCR-mediated signaling in mature T and iNKT lymphocytes
    Reiné, Jesús; Busto, Elena M.; Muñoz-Ruiz, Miguel ... Cellular immunology, 2011, 2011-00-00, 20110101, Volume: 271, Issue: 1
    Journal Article
    Peer reviewed

    ► We analyze signaling events in human CD3γ−/− primary and HVS-transformed T cells. ► CD3γ is dispensable for certain early signaling pathways and late iNKT cell functions. ► Other signaling pathways ...
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  • A leaky mutation in CD3D di... A leaky mutation in CD3D differentially affects [alpha][beta] and [gamma][delta] T cells and leads to a T[alpha][beta]-T[gamma][delta]+B+NK+ human SCID.(Brief report)(severe combined immunodeficiency)
    Gordillo, Isabel; Garcia-Rodriguez, Maria Cruz; Diaz-Alderete, Andrea ... The Journal of clinical investigation, 10/2011, Volume: 121, Issue: 10
    Journal Article
    Peer reviewed

    T cells recognize antigens via their cell surface TCR and are classified as either alphabeta or gammadelta depending on the variable chains in their TCR, alpha and betaor gamma and delta, ...
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  • A leaky mutation in CD3D di... A leaky mutation in CD3D differentially affects [alpha][Beta] and [gamma][delta] T cells and leads to a T[alpha][Beta]^sup -^T[gamma][delta]^sup +^B^sup +^NK^sup +^ human SCID
    Gil, Juana; Busto, Elena M; Garcillán, Beatriz ... The Journal of clinical investigation, 10/2011, Volume: 121, Issue: 10
    Journal Article
    Peer reviewed

    T cells recognize antigens via their cell surface TCR and are classified as either αbeta or γδ depending on the variable chains in their TCR, α and beta or γ and δ, respectively. Both αbeta and γδ ...
Full text
10.
  • Synthesis, conformational a... Synthesis, conformational analysis and assays of an anti-cancer vaccine that features an unnatural antigen based on an sp-iminosugar fragment
    Bermejo, Iris A; Navo, Claudio D; Castro-López, Jorge ... Chemical science (Cambridge), 04/2020, Volume: 11, Issue: 15
    Journal Article

    The Tn antigen (GalNAc-α-1- O -Thr/Ser) is a well-known tumor-associated carbohydrate determinant. The use of glycopeptides that incorporate this structure has become a significant and promising ...
Full text

PDF
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hits: 41

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