The study that we present is part of the preparation work for the setup of the FOOT (FragmentatiOn Of Target) experiment whose main goal is the measurement of the double differential cross sections ...of fragments produced in nuclear interactions of particles with energies relevant for particle therapy. The present work is focused on the characterization of the gas-filled drift chamber detector composed of 36 sensitive cells, distributed over two perpendicular views. Each view consists of six consecutive and staggered layers with three cells per layer. We investigated the detector efficiency and we performed an external calibration of the space–time relations at the level of single cells. This information was then used to evaluate the drift chamber resolution. An external tracking system realized with microstrip silicon detectors was adopted to have a track measurement independent on the drift chamber. The characterization was performed with a proton beam at the energies of 228 and 80 MeV. The overall hit detection efficiency of the drift chamber has been found to be 0.929±0.008, independent on the proton beam energy. The spatial resolution in the central part of the cell is about 150±10μ m and 300±10μ m and the corresponding detector angular resolution has been measured to be 1.62±0.16 mrad and 2.1±0.4 mrad for the higher and lower beam energies, respectively. In addition, the best value on the intrinsic drift chamber resolution has been evaluated to be in the range 60−100μ m. In the framework of the FOOT experiment, the drift chamber will be adopted in the pre-target region, and will be exploited to measure the projectile direction and position, as well as for the identification of pre-target fragmentation events.
Introduzione: Il delirium pediatrico, spesso identificato come sindrome di terapia intensiva, è associato ad una maggiore degenza ospedaliera ed all’insorgenza di sindromi post traumatiche e disturbi ...neuro cognitivi anche dopo l’ospedalizzazione. Mentre per i soggetti adulti o comunque con età superiore ai 12 anni i criteri diagnostici e gli strumenti validati per una diagnosi precoce sono ben delineati, in età pediatrica l’identificazione dei fattori predisponenti al delirium, è molto complicata. La specificità cognitiva della popolazione e l’esigua presenza di strumenti validati specifici, rendono tale sindrome fortemente sottostimata. Obiettivo: identificare specifici strumenti atti alla precoce individuazione dei fattori predisponenti il delirium pediatrico. Metodo: Revisione sistematica e Meta-analisi (se applicabile).A seconda della comparabilità degli studi reperiti, sarà condotta una meta-analisi. In tal caso, i risultati saranno riassunti in misure relative e assolute o differenza media, a seconda del tipo di risultato. Sarà effettuata l’analisi per la sensibilità ed eterogeneità. Conclusioni: l’identificazione di strumenti per lo screening precoce dei fattori predittivi del delirium in età pediatrica e specifico per le differenti fasce di età, potrà rappresentare uno strumento di supporto nella pratica clinica infermieristica e potrebbe determinare una rilevazione di questa sindrome spesso misconosciuta durante la degenza dei piccoli pazienti,permettendo l’erogazione di interventi assistenziali specifici da parte dell’equipe assistenziale.
Tau neutrinos are the least studied particle in the Standard Model. This whitepaper discusses the current and expected upcoming status of tau neutrino physics with attention to the broad experimental ...and theoretical landscape spanning long-baseline, beam-dump, collider, and astrophysical experiments. This whitepaper was prepared as a part of the NuTau2021 Workshop.
High fat and/or carbohydrate intake are associated with an elevated risk for obesity and chronic diseases such as diabetes and cardiovascular diseases. The harmful effects of a high fat diet could be ...different, depending on dietary fat quality. In fact, high fat diets rich in unsaturated fatty acids are considered less deleterious for human health than those rich in saturated fat. In our previous studies, we have shown that rats fed a high fat diet developed obesity and exhibited a decrease in oxidative capacity and an increase in oxidative stress in liver mitochondria. To investigate whether polyunsaturated fats could attenuate the above deleterious effects of high fat diets, energy balance and body composition were assessed after two weeks in rats fed isocaloric amounts of a high-fat diet (58.2% by energy) rich either in lard or safflower/linseed oil. Hepatic functionality, plasma parameters, and oxidative status were also measured. The results show that feeding on safflower/linseed oil diet attenuates the obesogenic effect of high fat diets and ameliorates the blood lipid profile. Conversely, hepatic steatosis and mitochondrial oxidative stress appear to be negatively affected by a diet rich in unsaturated fatty acids.
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