Dye effluents resulted from various industries are noxious both for the environment and for living beings. Therefore, contaminated wastewaters rise important concerns and require adequate treatment ...methodologies. In the last years, many procedures going from the advanced oxidation processes to the retention on different materials possessing adsorption properties were developed and applied for removing persistent dyes. Sorption of Congo Red dye was investigated in this paper. In the studied conditions, the adsorbent material prepared from cherry stones by physical activation through calcination was able to remove more than 90% of the targeted pollutant. Data fitted with high accuracy (correlation coefficient superior of 0.99) the pseudo-second-order kinetics and Freundlich isotherm model.
The present paper was dedicated to the study of endocrine disruptors removal from ultra-pure and real water solutions by adsorption on two types of activated carbon. This category of compounds ...includes natural substances such as hormones (reproductive, thyroid) or corticosteroids but also numerous chemicals as polycyclic aromatic hydrocarbons, dioxins, pharmaceuticals or pesticides. Their removal constitute an important preoccupation worldwide due to the fact that they are recognized as affecting the human health in a negative way. Among them, bisphenol A (BPA) and ethinylestradiol (EE2), are widely used for plastic and respectively for oral contraceptive pills production. The adsorption efficiencies of tested activated carbons on the BPA and EE2 removal were investigated using batch adsorption experiments. The recorded results revealed that the used adsorbents possess a high adsorption capacity (1521 μmol/g on NC90 and 1395 μmol/g on F400 for BPA and 1667μmol/g on NC90 and 1196 μmol/g on F400 for EE2) which recommends them for pollutant removal from real water.
Rhodospirillum rubrum was grown continuously and photoheterotrophically under light limitation using a cylindrical photobioreactor in which the steady state biomass concentration was varied between ...0.4 to 4 kg m(-3) at a constant radiant incident flux of 100 W m(-2). Kinetic and stoichiometric models for the growth are proposed. The biomass productivities, acetate consumption rate and the CO2 production rate can be quantitatively predicted to a high level of accuracy by the proposed model calculations.
Recent retrospective studies suggest potential large patient’s benefit through proper timing of immune checkpoint blockers (ICB). The association between ICB treatment timing and patient survival, ...neoplastic response and toxicities was investigated, together with interactions with performance status (PS) and sex.
A cohort of patients with metastatic or locally advanced solid tumors, who received pembrolizumab, nivolumab, atezolizumab, durvalumab, or avelumab, alone or with concomitant chemotherapy, between November 2015 and March 2021, at the Centre Leon Bérard (France), was retrospectively studied.
361 patients were investigated (80% non-small cell lung cancer patients, mean SD age: 63 11 years, 39% of women, 83% PS0–1 at first infusion, 19% received concomitant chemotherapy). ICB were administered from 07:25 to 17:21 and optimal morning/afternoon cut-off was 11:37. Morning infusions were associated with increased OS as compared to afternoon (median 30.3 vs 15.9 months, p = 0.0024; HR 1.56 1.17-2.1, p = 0.003). A strong PS-timing interaction was found (PS0-1 patients, HR=1.53 1.10-2.12, p = 0.011; PS2–3 patients, HR=0.50 0.25–0.97, p = 0.042). Morning PS0–1 patients displayed increased OS (median 36.7 vs 21.3 months, p = 0.023), partial/complete response rate (58% vs 41%, p = 0.027), and grade1–3 toxicities (49% vs 34%, p = 0.028). Mortality risk ratio between infusions at worst time-of-day, estimated at 13:36 12:48–14:23, and in early morning was equal to 4.8 (2.3-10.1, p = 0.008). Timing differences in toxicities resulted significant only in female patients (women vs men: p < 0.001 vs 0.4).
Early morning ICB infusion was associated with increased OS, response, and toxicities in patients with PS0–1 as compared to later infusions within the day. Prospective randomized trials are needed to confirm this retrospective study.
•Early morning Immune Checkpoint Blockade (ICB) was associated with increased survival and response.•All ICB timing differences were observed in patients with PS0-1 but not with PS2-3.•Best vs Worst ICB timing resulted in a-4.8-fold difference in patient mortality risk.•ICB toxicities were highly timing-dependent in women and not in men.
This paper presents a historical analysis of the development of the capacitating programs of the teachers of agriculture in the province of Guantánamo from the first of January 1959 until the year ...2015 taking into account the following indicators: content of the capacitating, forms of capacitating, and socioeconomic and productive conditions in which it develops. The results obtained constitute a reference material for the researchers of this topic.
En el presente trabajo se hace un análisis histórico del desarrollo de la superación de los profesores de Agropecuaria en la provincia de Guantánamo desde el primero de enero de 1959 hasta el año 2015 teniendo en cuenta los siguientes indicadores: contenido de la superación, formas de superación utilizadas, y condiciones socioeconómicas y productivas en que se desarrolla. Los resultados obtenidos constituyen un material de consulta para los investigadores de esta temática.
The prevalence of Yersinia enterocolitica in meat products was assessed by four methods: cold enrichment in trypticase soy broth (A), enrichment in modified Rappaport broth at 25 °C (B), ...concentration by immunomagnetic separation (C) and yadA nested PCR (D). Furthermore, the pathogenic potentials of the isolates were established by phenotypic and genotypic tests, and their genomic relationships were determined by pulsed-field gel electrophoresis (PFGE). A total of 238 samples were collected at retail level in the city of San Luis, Argentina, during the period 2007–2008. The highest Yersinia prevalence in meat products was observed by method D (92 positive samples), followed by methods A (13 positive samples) and C (5 positive samples); however, no isolation was obtained by method B. Fourteen Y. enterocolitica and 4 Yersinia intermedia strains were recovered by culture. All Y. enterocolitica 2/O:9 strains gave results related to virulence by phenotypic tests and exhibited the genotype virF+myfA+ail+ystA+. Two biotype 1A strains showed a genotype virF−myfA−ail+ystA+ystB+. The 14 Y. enterocolitica strains isolated during this work plus one reference strain were separated into 11 genomic types by PFGE. This genomic heterogeneity of the isolates shows the diversity of Y. enterocolitica strains in our region. It is the first time that IMS was used to search Y. enterocolitica strains from naturally contaminated meat products.
► Nested-PCR method showed the highest Yersinia prevalence in meat foods. ► Fourteen Yersinia enterocolitica (5.88%) and 4 Yersinia intermedia (1.68%) were recovered. ► All Y. enterocolitica 2/O:9 and some biotype 1A strains resulted to be virulent. ► A total of 11 genomic types (GTs) were obtained by PFGE.
Las insuficiencias que se revelan en las asignaturas técnicas para elaborar tareas docentes integradoras permitió considerar pertinente un sistema de acciones que garantice la preparación de los ...profesores en este sentido, elevar el nivel de aprendizaje de los estudiantes, y su mejor desempeño durante la práctica laboral. Se presenta un modelo de tarea docente integradora basado en los principios de profesionalización, fundamentalización y sistematización de la Enseñanza Técnica Profesional.
PDF
