Reverberation mapping measurements have been used to constrain the relationship between the size of the broad-line region and luminosity of active galactic nuclei (AGN). This \(R-L\) relation is used ...to estimate single-epoch virial black hole masses, and has been proposed for use to standardise AGN to determine cosmological distances. We present reverberation measurements made with H\(\beta\) from the six-year Australian Dark Energy Survey (OzDES) Reverberation Mapping Program. We successfully recover reverberation lags for eight AGN at \(0.12<z< 0.71\), probing higher redshifts than the bulk of H\(\beta\) measurements made to date. Our fit to the \(R-L\) relation has a slope of \(\alpha=0.41\pm0.03\) and an intrinsic scatter of \(\sigma=0.23\pm0.02\) dex. The results from our multi-object spectroscopic survey are consistent with previous measurements made by dedicated source-by-source campaigns, and with the observed dependence on accretion rate. Future surveys, including LSST, TiDES and SDSS-V, which will be revisiting some of our observed fields, will be able to build on the results of our first-generation multi-object reverberation mapping survey.
Programmed cell death, also known as apoptosis, is a normal physiologic process which occurs during embryonic development as well as in maintenance of tissue homeostasis. Increasing evidence suggests ...that alterations in cell death contribute to the pathogenesis of a number of human diseases, including cancer, viral infections, autoimmune diseases and acquired immunodeficiency syndrome (AIDS). The extraordinary research activity of the past few years has resulted in the characterization of the principal proteins involved in the apoptosis machinery. An area of particular interest has been the induction of apoptosis by two death receptor/ligand pairs, Fas/Fas Ligand and DR4-DR5/TRAIL. The identification of these molecules with the recruited signaling pathways could clarify their physiopathological implications, having a significant impact upon potential therapeutic interventions in diseases associated with cell survival alterations.
Como Coordinadora del Grupo de Ética de la Sociedad Española de Nutrición Clínica y Metabolismo (SENPE), me complace remitirle el documento elaborado por nuestro grupo de trabajo, del que nos ...sentimos especialmente satisfechos, en relación al tratamiento nutricional en la esclerosis lateral amiotrófica (ELA): MANEJO NUTRICIONAL DE LA ESCLEROSIS LATERAL AMIOTRÓFICA: RESUMEN DE RECOMENDACIONES. Agradeceríamos fuese valorado para publicación en el órgano de expresión de nuestra Sociedad, la revista Nutrición Hospitalaria, como documento de Grupos de Trabajo. Esperamos que dicho texto sea útil y sirva como guía terapéutica orientativa a los profesionales que tratan pacientes con dicha patología, en el ámbito de la Nutrición, y redunde en la mejoría de la atención a nuestros pacientes con ELA.
Mouse thymic dendritic cells (DC) have been isolated after collagenase digestion, selection of the low-density cell fraction, then depletion of T-lineage cells and other non-DC by treatment with ...specific monoclonal antibodies (mAb) and removal with anti-Ig-coated magnetic beads. The resulting DC preparation represented 0.1-0.2% of total thymic cells and contained 70-80% DC. Flow cytometry analysis of MHC class II (MHC II) expression by DC showed that 40% of DC expressed intermediate levels of MHC II, and 60% expressed high levels of this marker. Moreover, immunofluorescent 2-colour staining allowed the characterization of two clearly distinguishable DC subpopulations: MHC IIinter DC were CD45hi, CD44hi, HSAhi, whereas MHC IIhi DC were CD45lo, CD44lo, HSAlo. These results are discussed with regard to the functional significance of MHC IIinter and MHC IIhi DC subpopulations in the mouse thymus.
We cross-correlate positions of galaxies measured in data from the first three years of the Dark Energy Survey with Compton-\(y\)-maps generated using data from the South Pole Telescope (SPT) and the ...{\it Planck} mission. We model this cross-correlation measurement together with the galaxy auto-correlation to constrain the distribution of gas in the Universe. We measure the hydrostatic mass bias or, equivalently, the mean halo bias-weighted electron pressure \(\langle b_{h}P_{e}\rangle\), using large-scale information. We find \(\langle b_{h}P_{e}\rangle\) to be \(0.16^{+0.03}_{-0.04},0.28^{+0.04}_{-0.05},0.45^{+0.06}_{-0.10},0.54^{+0.08}_{-0.07},0.61^{+0.08}_{-0.06},0.63^{+0.07}_{-0.08}\) meV cm\(^{-3}\) at redshifts \(z \sim 0.30, 0.46, 0.62,0.77, 0.89, 0.97\). These values are consistent with previous work where measurements exist in the redshift range. We also constrain the mean gas profile using small-scale information, enabled by the high-resolution of the SPT data. We compare our measurements to different parametrized profiles based on the cosmo-OWLS hydrodynamical simulations. We find that our data are consistent with the simulation that assumes an AGN heating temperature of \(10^{8.5}\)K but are incompatible with the model that assumes an AGN heating temperature of \(10^{8.0}\)K. These comparisons indicate that the data prefer a higher value of electron pressure than the simulations within \(r_{500c}\) of the galaxies' halos.
We evaluate the consistency between lensing and clustering probes of large-scale structure based on measurements of projected galaxy clustering from BOSS combined with overlapping galaxy-galaxy ...lensing from three surveys: DES Y3, HSC Y1, and KiDS-1000. An intra-lensing-survey study finds good agreement between these lensing data. We model the observations using the Dark Emulator and fit the data at two fixed cosmologies: Planck, with \(S_8=0.83\), and a Lensing cosmology with \(S_8=0.76\). For a joint analysis limited to scales with \(R>5.25h^{-1}\)Mpc, we find that both cosmologies provide an acceptable fit to the data. Full utilisation of the small-scale clustering and lensing measurements is hindered by uncertainty in the impact of baryon feedback and assembly bias, which we account for with a reasoned theoretical error budget. We incorporate a systematic scaling parameter for each redshift bin, \(A\), that decouples the lensing and clustering to capture any inconsistency. When a wide range of scales (\(0.15<R<60h^{-1}\)Mpc) are incorporated, we find different results for the consistency of clustering and lensing between the two cosmologies. Limiting the analysis to the bins for which the impact of the selection of the lens sample is expected to be minimal, for the low-\(S_8\) Lensing cosmology, the measurements are consistent with \(A\)=1; \(A=0.91\pm0.04\) using DES+KiDS and \(A=0.97\pm0.06\) using HSC. For the Planck cosmology case, we find a discrepancy: \(A=0.79\pm0.03\) using DES+KiDS and \(A=0.84\pm0.05\) using HSC. We demonstrate that a kSZ-based estimate for baryonic effects alleviates some of the discrepancy in the Planck cosmology. This analysis demonstrates the statistical power of these small-scale measurements, but also indicates that caution is still warranted given current uncertainties in modelling baryonic effects, assembly bias, and selection effects in the foreground sample.
We characterise the properties and evolution of Bright Central Galaxies (BCGs) and the surrounding intracluster light (ICL) in galaxy clusters identified in overlapping regions of the Dark Energy ...Survey and Atacama Cosmology Telescope Survey (DES-ACT), covering the redshift range \(0.20<z<0.80\). Using this sample, we measure no change in the ICL's stellar content (between 50-300\,kpc) over this redshift range in clusters with log\(_{10}(M_{\rm 200m,SZ}\)/M\(_{\odot})>\)14.4. We also measure the stellar mass - halo mass (SMHM) relation for the BCG+ICL system and find that the slope, \(\beta\), which characterises the dependence of \(M_{\rm 200m,SZ}\) on the BCG+ICL stellar mass, increases with radius. The outskirts are more strongly correlated with the halo than the core, which supports that the BCG+ICL system follows a two-phase growth, where recent growth (\(z<2\)) occurs beyond the BCG's core. Additionally, we compare our observed SMHM relation results to the IllustrisTNG 300-1 cosmological hydrodynamic simulations and find moderate qualitative agreement in the amount of diffuse light. However, the SMHM relation's slope is steeper in TNG300-1 and the intrinsic scatter is lower, likely from the absence of projection effects in TNG300-1. Additionally, we find that the ICL exhibits a colour gradient such that the outskirts are bluer than the core. Moreover, for the lower halo mass clusters (log\(_{10}(M_{\rm 200m,SZ}\)/M\(_{\odot})<\)14.59 ), we detect a modest change in the colour gradient's slope with lookback time, which combined with the absence of stellar mass growth may suggest that lower mass clusters have been involved in growth via tidal stripping more recently than their higher mass counterparts.
In a strain of K. lactis , the RAG2 gene is found as a recessive allelic form, rag2 . The strain cannot grow on glucose if the respiratory pathway is blocked by mitochondrial inhibitors. The RAG2 ...gene has been cloned and its nucleotide sequence determined. The 557 amino acids long open reading frame has a homology of 56,5% with mouse neuroleukine which has recently been shown to be identical to the phosphoglucose isomerase.
Results are presented for six nuclei from Be to Pb on the structure function ratios
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2
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C(
x) and their
A dependence in deep inelastic muon scattering at 200 GeV incident muon energy. The data ...cover the kinematic range 0.01 <
x < 0.8 with
Q
2 ranging from 2 to 70 GeV
2. The
A dependence of nuclear structure function ratios is parametrised and compared to various models.
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