We present high signal-to-noise measurements of three-point shear correlations and the third moment of the mass aperture statistic using the first 3 years of data from the Dark Energy Survey. We ...additionally obtain the first measurements of the configuration and scale dependence of the four three-point shear correlations which carry cosmological information. With the third-order mass aperture statistic, we present tomographic measurements over angular scales of 4 to 60 arcminutes with a combined statistical significance of 15.0σ. Using the tomographic information and measuring also the second-order mass aperture, we additionally obtain a skewness parameter and its redshift evolution. We find that the amplitudes and scale-dependence of these shear 3pt functions are in qualitative agreement with measurements in a mock galaxy catalog based on N-body simulations, indicating promise for including them in future cosmological analyses. We validate our measurements by showing that B-modes, parity-violating contributions and PSF modeling uncertainties are negligible, and determine that the measured signals are likely to be of astrophysical and gravitational origin.
Abstract
We report the discovery of a stellar overdensity 8° north of the centre of the Small Magellanic Cloud (SMC; Small Magellanic Cloud Northern Over-Density; SMCNOD), using data from the first ...2 yr of the Dark Energy Survey (DES) and the first year of the MAGellanic SatelLITEs Survey (MagLiteS). The SMCNOD is indistinguishable in age, metallicity and distance from the nearby SMC stars, being primarily composed of intermediate-age stars (6 Gyr, Z=0.001), with a small fraction of young stars (1 Gyr, Z=0.01). The SMCNOD has an elongated shape with an ellipticity of 0.6 and a size of ∼ 6° × 2°. It has an absolute magnitude of MV ≅ −7.7, rh = 2.1 kpc, and μV(r < rh) = 31.2 mag arcsec−2. We estimate a stellar mass of ∼105 M⊙, following a Kroupa mass function. The SMCNOD was probably removed from the SMC disc by tidal stripping, since it is located near the head of the Magellanic Stream, and the literature indicates likely recent Large Magellanic Cloud-SMC encounters. This scenario is supported by the lack of significant H i gas. Other potential scenarios for the SMCNOD origin are a transient overdensity within the SMC tidal radius or a primordial SMC satellite in advanced stage of disruption.
Accurate estimation of tuber size distribution (TSD) parameters in discretely categorized potato (Solanum tuberosum L) yield samples is desirable for estimating modal tuber sizes, which is ...fundamental to yield prediction. In the current work, systematic yield digs were conducted on five commercial fields (N = 119) to compare the Weibull, Gamma and Gaussian distribution functions for relative-likelihood-based goodness-of-fit to the observed discrete distributions. Parameters were estimated using maximum likelihood estimation (MLE) for the three distributions but were also derived using the percentiles approach for the Weibull distribution to compare accuracy against the MLE approaches. The relationship between TSD and soil nutrient variability was examined using the best-fitting model's parameters. The percentiles approach had lower overall relative likelihood than the MLE approaches across five locations, but had consistently lower Root Mean Square Error in the marketable tuber size range. Negative relationships were observed between the percentile-based shape parameter and the concentrations of Phosphorus and Nitrogen, with significant (non-zero-overlapping 95% confidence interval) regression coefficients for P (−0.74 ± 0.33 for distribution of proportional tuber numbers and −1.3 ± 0.62 for tuber weights). Stem density was negatively associated with the scale and mode of tuber number (regression coefficients −0.98 ± 0.63 and −1.08 ± 0.78 respectively) and tuber weight (regression coefficients −0.99 ± 0.78 and −1.04 ± 0.69 respectively) distributions. Phosphorus is negatively related to the scale of the tuber-number-based distribution while positively associating with the tuber weight distribution. The results suggest that excess P application was associated with the increase in small tubers that did not contribute significant weight to the final yield.
We derive cosmological constraints from the probability distribution function (PDF) of evolved large-scale matter density fluctuations. We do this by splitting lines of sight by density based on ...their count of tracer galaxies, and by measuring both gravitational shear around and counts-in-cells in overdense and underdense lines of sight, in Dark Energy Survey (DES) First Year and Sloan Digital Sky Survey (SDSS) data. Our analysis uses a perturbation theory model O. Friedrich et al., Phys. Rev. D 98, 023508 (2018) and is validated using N-body simulation realizations and log-normal mocks. It allows us to constrain cosmology, bias and stochasticity of galaxies with respect to matter density and, in addition, the skewness of the matter density field. From a Bayesian model comparison, we find that the data weakly prefer a connection of galaxies and matter that is stochastic beyond Poisson fluctuations on ≤20 arcmin angular smoothing scale. The two stochasticity models we fit yield DES constraints on the matter density Ωm=0.26−0.03+0.04 and Ωm=0.28−0.04+0.05 that are consistent with each other. These values also agree with the DES analysis of galaxy and shear two-point functions (3x2pt, DES Collaboration et al.) that only uses second moments of the PDF. Constraints on σ8 are model dependent (σ8=0.97−0.06+0.07 and 0.80−0.07+0.06 for the two stochasticity models), but consistent with each other and with the 3 x 2pt results if stochasticity is at the low end of the posterior range. As an additional test of gravity, counts and lensing in cells allow to compare the skewness S3 of the matter density PDF to its ΛCDM prediction. We find no evidence of excess skewness in any model or data set, with better than 25 per cent relative precision in the skewness estimate from DES alone.
Neurofibromatosis type 1 (NF1) is a common tumor-predisposition disorder due to germline mutations in the tumor suppressor gene NF1. A virtually pathognomonic finding of NF1 is the plexiform ...neurofibroma (PN), a benign, likely congenital tumor that arises from bi-allelic inactivation of NF1. PN can undergo transformation to a malignant peripheral nerve sheath tumor, an aggressive soft-tissue sarcoma. To better understand the non-NF1 genetic contributions to PN pathogenesis, we performed whole-exome sequencing, RNASeq profiling and genome-wide copy-number determination for 23 low-passage Schwann cell cultures established from surgical PN material with matching germline DNA. All resected tumors were derived from routine debulking surgeries. None of the tumors were considered at risk for malignant transformation at the time; for example, there was no pain or rapid growth. Deep (~500X) NF1 exon sequencing was also conducted on tumor DNA. Non-NF1 somatic mutation verification was performed using the Ampliseq/IonTorrent platform. We identified 100% of the germline NF1 mutations and found somatic NF1 inactivation in 74% of the PN. One individual with three PNs had different NF1 somatic mutations in each tumor. The median number of somatic mutations per sample, including NF1, was one (range 0-8). NF1 was the only gene that was recurrently somatically inactivated in multiple tumors. Gene Set Enrichment Analysis of transcriptome-wide tumor RNA sequencing identified five significant (FDR<0.01) and seven trending (0.01⩽FDR<0.02) gene sets related to DNA replication, telomere maintenance and elongation, cell cycle progression, signal transduction and cell proliferation. We found no recurrent non-NF1 locus copy-number variation in PN. This is the first multi-sample whole-exome and whole-transcriptome sequencing study of NF1-associated PN. Taken together with concurrent copy-number data, our comprehensive genetic analysis reveals the primacy of NF1 loss as the driver of PN tumorigenesis.
We use the UKIDSS Ultra Deep Survey to trace the evolution of galaxy clustering to z= 3. Using photometric redshifts derived from data covering the wavelength range 0.3–4.5 μm, we examine this ...clustering as a function of absolute K-band luminosity, colour and star formation rate. Comparing the deprojected clustering amplitudes, we find that red galaxies are more strongly clustered than blue galaxies out to at least z= 1.5, irrespective of rest-frame K-band luminosity. We then construct passive and star-forming samples based on stellar age, colour and star formation histories calculated from the best-fitting templates. The clustering strength of star-forming galaxies declines steadily from r0≃ 7 h−1 Mpc at z≃ 2 to r0≃ 3 h−1 Mpc at z≃ 0, while passive galaxies have clustering strengths up to a factor of 2 higher. Within the passive and star-forming subsamples, however, we find very little dependence of galaxy clustering on K-band luminosity. Galaxy ‘passivity’ appears to be the strongest indicator of clustering strength. We compare these clustering measurements with those predicted for dark matter haloes and conclude that passive galaxies typically reside in haloes of mass M≥ 1013 M⊙ while luminous star-forming galaxies occupy haloes an order of magnitude less massive over the range 0.5 < z < 1.5. The decline in the clustering strength of star-forming galaxies with decreasing redshift indicates a decline in the hosting halo mass for galaxies of a given luminosity. We find evidence for convergence of clustering in star-forming and passive galaxies around z∼ 2, which is consistent with this being the epoch at which the red sequence of galaxies becomes distinct.
We investigate the effects of dense environments on galaxy evolution by examining how the properties of galaxies in the z = 1.6 protocluster Cl 0218.3-0510 depend on their location. We determine ...galaxy properties using spectral energy distribution fitting to 14-band photometry, including data at three wavelengths that tightly bracket the Balmer and 4000 A breaks of the protocluster galaxies. We find that two-thirds of the protocluster galaxies, which lie between several compact groups, are indistinguishable from field galaxies. The other third, which reside within the groups, differ significantly from the intergroup galaxies in both colour and specific star formation rate. We find that the fraction of red galaxies within the massive protocluster groups is twice that of the intergroup region. These excess red galaxies are due to enhanced fractions of both passive galaxies (1.7 times that of the intergroup region) and dusty star-forming galaxies (3 times that of the intergroup region). We infer that some protocluster galaxies are processed in the groups before the cluster collapses. These processes act to suppress star formation and change the mode of star formation from unobscured to obscured.
Abstract
Measurements of the galaxy stellar mass function are crucial to understand the formation of galaxies in the Universe. In a hierarchical clustering paradigm, it is plausible that there is a ...connection between the properties of galaxies and their environments. Evidence for environmental trends has been established in the local Universe. The Dark Energy Survey (DES) provides large photometric data sets that enable further investigation of the assembly of mass. In this study, we use ∼3.2 million galaxies from the (South Pole Telescope) SPT-East field in the DES science verification (SV) data set. From grizY photometry, we derive galaxy stellar masses and absolute magnitudes, and determine the errors on these properties using Monte Carlo simulations using the full photometric redshift probability distributions. We compute galaxy environments using a fixed conical aperture for a range of scales. We construct galaxy environment probability distribution functions and investigate the dependence of the environment errors on the aperture parameters. We compute the environment components of the galaxy stellar mass function for the redshift range 0.15 < z < 1.05. For z < 0.75, we find that the fraction of massive galaxies is larger in high-density environment than in low-density environments. We show that the low-density and high-density components converge with increasing redshift up to z ∼ 1.0 where the shapes of the mass function components are indistinguishable. Our study shows how high-density structures build up around massive galaxies through cosmic time.
Although RNA-Seq data provide unprecedented isoform-level expression information, detection of alternative isoform regulation (AIR) remains difficult, particularly when working with an incomplete ...transcript annotation. We introduce JunctionSeq, a new method that builds on the statistical techniques used by the well-established DEXSeq package to detect differential usage of both exonic regions and splice junctions. In particular, JunctionSeq is capable of detecting differential usage of novel splice junctions without the need for an additional isoform assembly step, greatly improving performance when the available transcript annotation is flawed or incomplete. JunctionSeq also provides a powerful and streamlined visualization toolset that allows bioinformaticians to quickly and intuitively interpret their results. We tested our method on publicly available data from several experiments performed on the rat pineal gland and Toxoplasma gondii, successfully detecting known and previously validated AIR genes in 19 out of 19 gene-level hypothesis tests. Due to its ability to query novel splice sites, JunctionSeq is still able to detect these differences even when all alternative isoforms for these genes were not included in the transcript annotation. JunctionSeq thus provides a powerful method for detecting alternative isoform regulation even with low-quality annotations. An implementation of JunctionSeq is available as an R/Bioconductor package.
We present the results of a new and improved study of the morphological and spectral evolution of massive galaxies over the redshift range 1 < z < 3. Our analysis is based on a bulge–disc ...decomposition of 396 galaxies with M
* > 1011 M⊙ uncovered from the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS) Wide Field Camera 3 (WFC3)/IR imaging within the Cosmological Evolution Survey (COSMOS) and UKIRT Infrared Deep Sky Survey (UKIDSS) UDS survey fields. We find that, by modelling the H
160 image of each galaxy with a combination of a de Vaucouleurs bulge (Sérsic index n = 4) and an exponential disc (n = 1), we can then lock all derived morphological parameters for the bulge and disc components, and successfully reproduce the shorter-wavelength J
125, i
814, v
606
HST images simply by floating the magnitudes of the two components. This then yields sub-divided four-band HST photometry for the bulge and disc components which, with no additional priors, is well described by spectrophotometric models of galaxy evolution. Armed with this information, we are able to properly determine the masses and star formation rates for the bulge and disc components, and find that: (i) from z = 3 to 1 the galaxies move from disc dominated to increasingly bulge dominated, but very few galaxies are pure bulges/ellipticals by z = 1; (ii) while most passive galaxies are bulge dominated, and most star-forming galaxies disc dominated, 18 ± 5 per cent of passive galaxies are disc dominated, and 11 ± 3 per cent of star-forming galaxies are bulge dominated, a result which needs to be explained by any model purporting to connect star formation quenching with morphological transformations; (iii) there exists a small but significant population of pure passive discs, which are generally flatter than their star-forming counterparts (whose axial ratio distribution peaks at b/a ≃ 0.7); (iv) flatter/larger discs re-emerge at the highest star formation rates, consistent with recent studies of sub-mm galaxies, and with the concept of a maximum surface density for star formation activity.