The aim of this study was to evaluate inter-reader, intra-investigator and inter-investigator reproducibility and correlations in the assessment of substantia nigra (SN) echogenicity and area ...measurement by a physician-sonographer (PS), a sonographic laboratory assistant (SLA) and a physician without sonographic experience (PN). A total of 22 patients with extrapyramidal symptoms were examined using transcranial sonography (TCS). SN images were encoded and evaluated by the three readers. A second TCS examination was performed after 7+/-2 d. A second investigator performed TCS examination 1 mo later. Spearman rank correlation and Pearson's correlation coefficient were used when assessing the agreement between readers. All three readers identified the same 15 patients with SN echogenicity III or more. Inter-reader SN echogenicity and area measurement correlations were r=0.55 to 0.82 and r=0.31 to 0.74 between PS and SLA and r=0.55 to 0.77 and 0.49 to 0.62 between PS and PN, respectively (p<0.05 in all cases). Intra-reader echogenicity and area measurement correlations (r=0.85 to 0.96 and r=0.51 to 0.69) were statistically significant only for PS (p<0.001). All intra- and inter-investigator correlations of SN area measurement (r=0.69 to 0.88 and r=0.5 to 0.61) and SN echogenicity (r=0.64 to 0.92 and r=0.51 to 0.69) were statistically significant (p<0.05). Semiquantitative evaluation of SN echogenicity and area using TCS is highly dependent on the experience of the sonographer. Only an experienced sonographer was able to produce very reproducible results with statistically significant correlations; SLA and PN intra-reader correlations were poor.
Der gegenwärtigen Medienlandschaft wird häufig eine Tendenz zur Offenlegung und Offenheit zugeschrieben. Social Network Sites lassen die Grenzen zwischen Privatem und Öffentlichem verschwimmen, ...Plattformen wie WikiLeaks und OpenLeaks veröffentlichen geheimes Material, über Filesharing-Netzwerke und open-content-Lizenzen werden vormals proprietäre Inhalte offen zugänglich gemacht. Verflochten sind diese Entwicklungen mit auf den ersten Blick gegenläufigen Tendenzen der Eingrenzung, der Kontrolle und der Schließung. Kommunikation im Internet bindet sich immer mehr an die Vermittlung einzelner privatwirtschaftlicher Akteure wie Google oder Facebook, online wie offline ermöglichen neue Informations- und Kommunikationstechnologien immer umfassendere Formen der Überwachung, während die Weiterverwendung von Daten unter Ausschluss der Öffentlichkeit stattfindet. Die Beiträge des vorliegenden Bandes befassen sich mit unterschiedlichen Aspekten dieses komplexen Spannungsfeldes.
Transcranial sonography in movement disorders Bartova, Petra; Skoloudik, David; Bar, Michal ...
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia,
12/2008, Volume:
152, Issue:
2
Journal Article
Peer reviewed
Open access
Transcranial sonography (TCS) in the B-mode has the ability to image, infratentorial and supratentorial brain structures. For this reason, it has potential use in the diagnosis and differential ...diagnosis of various intracranial pathologies.
The authors reviewed the contribution of TCS to the differentiation of a number of neurodegenerative diseases: in parkinsonian syndromes, TCS can evaluate echogenicity changes in specific structures such as the hyperechogenic area of the substantia nigra (SN) in Parkinson's disease and the hyperechogenic caudate nucleus in Huntington's disease as well as the hyperechogenic lentiform nucleus (LN) in dystonia and Wilson's disease. In parkinson-plus syndromes, TCS may detect changes in width of the third ventricle and of the frontal horns of the lateral ventricle. The hyperechogenic SN can also be used in healthy populations as a marker of subclinical injury to the nigrostriatal system.
TCS is a quick, safe and non-invasive method. It could be helpful in differentiation between several movement disorders together with clinical examination and other neuroimaging methods.
Social anxiety is highly prevalent but goes untreated. Although school-based CBT programs are efficacious when delivered by specialized psychologists, it is unclear whether school counselors can ...implement these interventions effectively, which is essential to promote sustainable school programs. We present an initial consultation strategy to support school counselor implementation of group CBT for social anxiety and an evaluation of counselors’ treatment fidelity. Counselors were highly adherent to the treatment, but competence varied based on measurement. Counselors and consultants demonstrated good agreement for adherence, but relatively modest correspondence in competence ratings. We discuss future directions for school-based implementation efforts informed by these initial findings.
Provider: Czech digital library/Česká digitální knihovna - Institution: National Medical Library/Národní lékařská knihovna - Data provided by Europeana Collections- Hyperechogenní a rozšířená oblast ...substantia nigra je detekovatelná u více než 90 % pacientů s Parkinsonovou nemocí (PN). U zdravé populace se však tento nález vyskytuje maximálně v 10 %. Cílem naším práce bylo zjistit zastoupení nálezu hyperechogenní či rozšířené substantia nigra u pacientů s atypickým parkinsonským syndromem (APS). Metodika: Během 15 měsíců jsme vyšetřili pomocí transkraniální sonografie 209 pacientů s PN, multisystémovou atrofií (MSA), vaskulárním parkinsonským syndromem (VP) a esenciálním tremorem (ET). Jako kontrolní skupina byli vybráni pacienti s prokázanou PN a zdraví dobrovolníci. Výsledky: Hyperechogenní SN byla nalezena u 42,9 % u pacientů s MSA, 10 % u ET, a 18,2 % u VP. Rozšířená oblast SN větší než 0,25 cm2 byla detekována u pacientů s MSA v 50 %, u VP ve 20 % a u ET ve 27,3 %. Hyperechogenní, rozšířená SN byla signifikantně častější u PN (84,7 %) a MSA (50 %) (p > 0,05) ve srovnání s VP (27,3 %), ET (20 %) a zdravými dobrovolníky (0 %). Závěr: Nález hyperechogenní, rozšířená oblast SN je signifikantně častější u pacientů s PN a MSA. TCS detekce SN může být použita jako další metoda v diferenciální diagnostice PN a atypických parkinsonských syndromů.- Petra Bártová, D. Školoudík, T. Fadrná, P. Ressner, M. Bar, R. Herzig, P. Kaňovský- Lit.: 18- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
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