I propose, as geometric structure in an internal space, a helical field that is responsible for intrinsic properties of point particles, particularly, electron. For the novel theoretical development, ...plasma astrophysical analogy is made extensively. Transition between our conventional space and the infinitesimal space is considered in an operational manner. It is shown that rotational eigenvalue equation satisfied by the vector field equivalent to Gromeka-Beltrami flow provides a coordinate-rotor that captures complex orthogonality between the internal coordinate space and isotopic, angular momentum space. Self-consistent normalization of rotational coordinate owing to the rotor is compared to renormalization of electric charge. It is also found that chiral asymmetry of the helical eigenflows can be reflected in electroweak symmetry breaking. The theoretical prototype suggests possible geometrical features of a fundamental framework ruling matters and forces with higher dimensions.
We present high-resolution H-band polarized intensity (FWHM = 0".1:14 AU) and L'-band imaging data (FWHM = 0".11: 15 AU) of the circumstellar disk around the weak-lined T Tauri star PDS 70 in ...Centaurus at a radial distance of 28 AU (0".2) up to 210 AU (1".5). In both images, a giant inner gap is clearly resolved for the first time, and the radius of the gap is ~70 AU. Our data show that the geometric center of the disk shifts by ~6 AU toward the minor axis. We confirm that the brown dwarf companion candidate to the north of PDS 70 is a background star based on its proper motion. As a result of spectral energy distribution fitting by Monte Carlo radiative transfer modeling, we infer the existence of an optically thick inner disk at a few AU. Combining our observations and modeling, we classify the disk of PDS 70 as a pre-transitional disk. Furthermore, based on the analysis of L'-band imaging data, we put an upper limit of ~30 to ~50 M sub(J) on the mass of companions within the gap. Taking into account the presence of the large and sharp gap, we suggest that the gap could be formed by dynamical interactions of sub-stellar companions or multiple unseen giant planets in the gap.
We report high-resolution 1.6 Delta *mm polarized intensity (PI) images of the circumstellar disk around the Herbig Ae star AB Aur at a radial distance of 22 AU (015) up to 554 AU (385), which have ...been obtained by the high-contrast instrument HiCIAO with the dual-beam polarimetry. We revealed complicated and asymmetrical structures in the inner part (140 AU) of the disk while confirming the previously reported outer (r 200 AU) spiral structure. We have imaged a double ring structure at ~40 and ~100 AU and a ring-like gap between the two. We found a significant discrepancy of inclination angles between two rings, which may indicate that the disk of AB Aur is warped. Furthermore, we found seven dips (the typical size is ~45 AU or less) within two rings, as well as three prominent PI peaks at ~40 AU. The observed structures, including a bumpy double ring, a ring-like gap, and a warped disk in the innermost regions, provide essential information for understanding the formation mechanism of recently detected wide-orbit (r > 20 AU) planets.
Piwi-interacting RNAs (piRNAs) silence transposons in animal germ cells. piRNAs are thought to derive from long transcripts spanning transposon-rich genomic loci and to direct an autoamplification ...loop in which an antisense piRNA, bound to Aubergine or Piwi protein, triggers production of a sense piRNA bound to the PIWI protein Argonaute3 (Ago3). In turn, the new piRNA is envisioned to produce a second antisense piRNA. Here, we describe strong loss-of-function mutations in
ago3, allowing a direct genetic test of this model. We find that Ago3 acts to amplify piRNA pools and to enforce on them an antisense bias, increasing the number of piRNAs that can act to silence transposons. We also detect a second, Ago3-independent piRNA pathway centered on Piwi. Transposons targeted by this second pathway often reside in the
flamenco locus, which is expressed in somatic ovarian follicle cells, suggesting a role for piRNAs beyond the germline.
We present high-resolution, H-band imaging observations, collected with Subaru/HiCIAO, of the scattered light from the transitional disk around SAO 206462 (HD 135344B). Although previous sub-mm ...imagery suggested the existence of a dust-depleted cavity at r < or =, slant 46 AU, our observations reveal the presence of scattered light components as close as 0".2 (~28 AU) from the star. Moreover, we have discovered two small-scale spiral structures lying within 0".5 (~70 AU). We present models for the spiral structures using the spiral density wave theory, and derive a disk aspect ratio of h ~ 0.1, which is consistent with previous sub-mm observations. This model can potentially give estimates of the temperature and rotation profiles of the disk based on dynamical processes, independently from sub-mm observations. It also predicts the evolution of the spiral structures, which can be observable on timescales of 10-20 years, providing conclusive tests of the model. While we cannot uniquely identify the origin of these spirals, planets embedded in the disk may be capable of exciting the observed morphology. Assuming that this is the case, we can make predictions on the locations and, possibly, the masses of the unseen planets. Such planets may be detected by future multi-wavelength observations.
Mitochondria play a key role in determining cell fate during exposure to stress. Their role during ischemia/reperfusion is particularly critical because of the conditions that promote both apoptosis ...by the mitochondrial pathway and necrosis by irreversible damage to mitochondria in association with mitochondrial permeability transition (MPT). MPT is caused by the opening of permeability transition pores in the inner mitochondrial membrane, leading to matrix swelling, outer membrane rupture, release of apoptotic signaling molecules such as cytochrome c from the intermembrane space, and irreversible injury to the mitochondria. During ischemia (the MPT priming phase), factors such as intracellular Ca2+ accumulation, long-chain fatty acid accumulation, and reactive oxygen species progressively increase mitochondrial susceptibility to MPT, increasing the likelihood that MPT will occur on reperfusion (the MPT trigger phase). Because functional cardiac recovery ultimately depends on mitochondrial recovery, cardioprotection by ischemic and pharmacological preconditioning must ultimately involve the prevention of MPT. Investigations into this area are beginning to unravel some of the mechanistic links between cardioprotective signaling and mitochondria.
The evolution of young massive protoplanetary disks toward planetary systems is expected to correspond to structural changes in observational appearance, which includes the formation of gaps and the ...depletion of dust and gas. A special group of disks around Herbig Ae/Be stars do not show prominent silicate emission features, although they still bear signs of flaring disks, the presence of gas, and small grains. We focus our attention on four key Herbig Ae/Be stars to understand the structural properties responsible for the absence of silicate feature emission. The absence of silicate emission features is due to the presence of large gaps in the critical temperature regime. Many, if not all Herbig disks with spectral energy distribution classification "group I", are disks with large gaps and can be characterized as (pre-)transitional. An evolutionary path from the observed group I to the observed group II sources seems no longer likely. Instead, both might derive from a common ancestor.
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