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  • On the BFGS monolithic algo... On the BFGS monolithic algorithm for the unified phase field damage theory
    Wu, Jian-Ying; Huang, Yuli; Nguyen, Vinh Phu Computer methods in applied mechanics and engineering, 03/2020, Volume: 360
    Journal Article
    Peer reviewed

    Despite the popularity in modeling complex and arbitrary crack configurations in solids, phase-field damage models suffer from burdensome computational cost. This issue arises largely due to the ...
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  • Comprehensive implementatio... Comprehensive implementations of phase-field damage models in Abaqus
    Wu, Jian-Ying; Huang, Yuli Theoretical and applied fracture mechanics, April 2020, 2020-04-00, 20200401, Volume: 106
    Journal Article
    Peer reviewed

    •Three different implementation strategies of phase-field damage models in Abaqus are addressed.•The sources codes and input files of all these three implementation schemes can be open ...
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  • A variationally consistent ... A variationally consistent phase-field anisotropic damage model for fracture
    Wu, Jian-Ying; Nguyen, Vinh Phu; Zhou, Hao ... Computer methods in applied mechanics and engineering, 01/2020, Volume: 358
    Journal Article
    Peer reviewed

    In the phase-field modeling of fracture in brittle and quasi-brittle solids, it is crucial to represent the asymmetric tensile/compressive material behavior. Existing phase-field models generally ...
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  • Methodological implementati... Methodological implementation of mixed linear models in multi-locus genome-wide association studies
    Wen, Yang-Jun; Zhang, Hanwen; Ni, Yuan-Li ... Briefings in bioinformatics, 07/2018, Volume: 19, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Abstract The mixed linear model has been widely used in genome-wide association studies (GWAS), but its application to multi-locus GWAS analysis has not been explored and assessed. Here, we ...
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  • Three-dimensional phase-fie... Three-dimensional phase-field modeling of mode I + II/III failure in solids
    Wu, Jian-Ying; Huang, Yuli; Zhou, Hao ... Computer methods in applied mechanics and engineering, 01/2021, Volume: 373
    Journal Article
    Peer reviewed

    One major merit of phase-field models for fracture is that cracks nucleation, propagation, branching, merging, coalescence and even fragmentation, etc., can be accounted for seamlessly within a ...
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  • Immunogenicity and safety o... Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: a randomised, double-blind, placebo-controlled, phase 2 trial
    Zhu, Feng-Cai; Guan, Xu-Hua; Li, Yu-Hua ... The Lancet (British edition), 08/2020, Volume: 396, Issue: 10249
    Journal Article
    Peer reviewed
    Open access

    This is the first randomised controlled trial for assessment of the immunogenicity and safety of a candidate non-replicating adenovirus type-5 (Ad5)-vectored COVID-19 vaccine, aiming to determine an ...
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  • Improving power and accurac... Improving power and accuracy of genome-wide association studies via a multi-locus mixed linear model methodology
    Wang, Shi-Bo; Feng, Jian-Ying; Ren, Wen-Long ... Scientific reports, 01/2016, Volume: 6, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Genome-wide association studies (GWAS) have been widely used in genetic dissection of complex traits. However, common methods are all based on a fixed-SNP-effect mixed linear model (MLM) and single ...
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  • Synergistic Modulation of E... Synergistic Modulation of Electronic Interaction to Enhance Intrinsic Activity and Conductivity of Fe-Co-Ni Hydroxide Nanotube for Highly Efficient Oxygen Evolution Electrocatalyst
    Huang, Huanfeng; Ning, Shunlian; Xie, Yanyu ... Small (Weinheim an der Bergstrasse, Germany), 09/2023, Volume: 19, Issue: 36
    Journal Article
    Peer reviewed
    Open access

    The large-scale hydrogen production and application through electrocatalytic water splitting depends crucially on the development of highly efficient, cost-effective electrocatalysts for oxygen ...
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  • 3D cell culture models: Dru... 3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration
    Wang, Hongbing; Brown, Paul C.; Chow, Edwin C.Y. ... Clinical and translational science, September 2021, Volume: 14, Issue: 5
    Journal Article
    Peer reviewed
    Open access

    Nonclinical testing has served as a foundation for evaluating potential risks and effectiveness of investigational new drugs in humans. However, the current two‐dimensional (2D) in vitro cell culture ...
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  • The pharmacology, toxicolog... The pharmacology, toxicology and therapeutic potential of anthraquinone derivative emodin
    CUI, Ya; CHEN, Liu-Jing; HUANG, Tu ... Chinese journal of natural medicines, June 2020, 2020-06-00, 20200601, Volume: 18, Issue: 6
    Journal Article

    Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is a derived anthraquinone compound extracted from roots and barks of pharmaceutical plants, including Rheum palmatum, Aloe vera, Giant knotweed, ...
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