We present the update of the SModelS database with the simplified model results from CMS searches for supersymmetry at Run 2 with 36 fb−1 of data. The constraining power of these new results is ...compared to that of the 8 TeV results within the context of a full model, the pMSSM. The new database, v1.1.2, is publicly available and can readily be employed for physics studies with SModelS.
Natural SUSY at LHC with right-sneutrino LSP Chatterjee, Arindam; Dutta, Juhi; Rai, Santosh Kumar
The journal of high energy physics,
06/2018, Volume:
2018, Issue:
6
Journal Article
Peer reviewed
Open access
A
bstract
We study an extension of the minimal supersymmetric standard model (MSSM) with additional right-handed singlet neutrino superfields. While such an extension incorporates a mechanism for the ...neutrino mass, it also opens up the possibility of having the right-sneutrinos (
ν
˜
) as the lightest supersymmetric particle (LSP). In this work, we focus on the viability of rather small (≲500 GeV) higgsino mass parameter (
μ
), an important ingredient for “naturalness”, in the presence of such a LSP. For simplicity, we assume that the bino and wino mass parameters are much heavier; thus we only consider (almost) pure and compressed higgsino-like states, with small
O
1
0
−
2
gaugino admixture which nevertheless still affect the decay of the low-lying higgsino-like states, thus significantly affecting the proposed signatures at colliders. Considering only prompt decays of the higgino-like states, especially the lightest chargino, we discuss the importance of leptonic channels consisting of up to two leptons with large missing transverse energy to probe this scenario at the Large Hadron Collider (LHC). In addition we also comment on the dark matter predictions for the studied scenario.
A
bstract
Search for compressed supersymmetry at multi-TeV scale, in the presence of a light gravitino dark matter, can get sizable uplift while looking into the associated fat- jets with missing ...transverse momenta as a signature of the boson produced in the decay process of much heavier next-to-lightest sparticle. We focus on the hadronic decay of the ensuing Higgs and/or
Z
boson giving rise to at least two fat-jets and
in the final state. We perform a detailed background study adopting a multivariate analysis using a boosted decision tree to provide a robust investigation to explore the discovery potential for such signal at 14 TeV LHC considering different benchmark points satisfying all the theoretical and experimental constraints. This channel provides the best discovery prospects with most of the benchmarks discoverable within an integrated luminosity of
ℒ
= 200 fb
−
1
. Kinematic observables are investigated in order to distinguish between compressed and uncompressed spectra having similar event yields.
A
bstract
Presence of the light gravitino as dark matter candidate in a supersymmetric (SUSY) model opens up interesting collider signatures consisting of one or more hard photons together with ...multiple jets and missing transverse energy from the cascade decay. We investigate such signals at the 13 TeV LHC in presence of compressed SUSY spectra, consistent with the Higgs mass as well as collider and dark matter constraints. We analyse and compare the discovery potential in different benchmark scenarios consisting of both compressed and uncompressed SUSY spectra, considering different levels of compression and intermediate decay modes. Our conclusion is that compressed spectra upto 2.5 TeV are likely to be probed even before the high luminosity run of LHC. Kinematic variables are also suggested, which offer distinction between compressed and uncompressed spectra yielding similar event rates for photons + multi-jets +
.
Long-term storage and stability of DNA is of paramount importance in biomedical applications. Ever since the emergence of ionic liquids (ILs) as alternate green solvents to aqueous and organic ...solvents, their exploration for the extraction and application of DNA need conscientious understanding of the binding characteristics and molecular interactions between IL and DNA. Choline amino acid ILs (CAAILs) in this regard seem to be promising due to their non-cytotoxic, completely biobased and environment-friendly nature. To unravel the key factors for the strength and binding mechanism of CAAILs with DNA, various spectroscopic techniques, molecular docking, and molecular dynamics simulations were employed in this work. UV–Vis spectra indicate multimodal binding of CAAILs with DNA, whereas dye displacement studies through fluorescence emission confirm the intrusion of IL molecules into the minor groove of DNA. Circular dichorism spectra show that DNA retains its native B-conformation in CAAILs. Both isothermal titration calorimetry and molecular docking studies provide an estimate of the binding affinity of DNA with CAAILs ≈ 4 kcal/mol. The heterogeneity in binding modes of CAAIL-DNA system with evolution of time was established by molecular dynamics simulations. Choline cation while approaching DNA first binds at surface through electrostatic interactions, whereas a stronger binding at minor groove occurs via van der Waals and hydrophobic interactions irrespective of anions considered in this study. We hope this result can encourage and guide the researchers in designing new bio-ILs for biomolecular studies in future.
Dark Matter phenomenology in 2HDMS Moortgat-Pick, Gudrid; Dutta, Juhi; Li, Cheng ...
SciPost physics proceedings,
09/2023
12
Journal Article
Peer reviewed
Open access
The constituents of dark matter are still an unresolved puzzle. Several Beyond Standard Model (BSM) Physics offer suitable candidates. In this study here we consider the Two Higgs Doublet model ...augmented with a complex scalar singlet (2HDMS) and focus on the dark matter phenomenology of 2HDMS with the complex scalar singlet as the dark matter candidate. The parameter space allowed from existing experimental constraints from dark matter, flavour physics and collider searches has been studied. The discovery potential for such a 2HDMS at HL-LHC and at future
e^+e^-
e
+
e
−
colliders has been worked out.
Branched DNA (bDNA) nanostructures have emerged as self-assembled biomaterials and are being considered for biomedical applications. Herein, we report the biophysical interaction between ...self-assembled bDNA nanostructure with circulating protein bovine serum albumin (BSA) and cellular enzyme bovine liver catalase (BLC). The binding between bDNA and BSA or BLC was confirmed through the decrease in fluorescence spectra. The Stern-Volmer data supports for non-covalent bonding with ~1 binding site in case of BSA and BLC thus advocating a static binding. Furthermore, FTIR and ITC study confirmed the binding of bDNAs with proteins through hydrogen bonding and van der Waals interaction. The negative free energy observed in ITC represent spontaneous reaction for BLC-bDNA interaction. The biophysical interaction between bDNA nanostructures and proteins was also supported by DLS and zeta potential measurement. With an increase in bDNA concentrations up to 100 nM, no significant change in absorbance and CD spectra was observed for both BLC and BSA which suggests structural stability and unaffected secondary conformation of proteins in presence of bDNA. Furthermore, the catalytic activity of BLC was unaltered in presence of bDNAscr even with increasing the incubation period from 1 h to 24 h. Interestingly, the time-dependent decrease in activity of BLC was protected by bDNAmix. The thermal melting study suggests a higher Tm value for proteins in presence of bDNAmix which demonstrates that interaction with bDNAmix increases the thermal stability of proteins. Collectively these data suggest that self-assembled DNA nanostructure may bind to BSA for facilitating circulation in plasma or binding to intracellular proteins like BLC for stabilization, however the secondary conformation of protein or catalytic activity of enzyme is unaltered in presence of bDNA nanostructure. Thus, the newly established genomic sequence-driven self-assembled DNA nanostructure can be explored for in vitro or in vivo experimental work in recent future.
Display omitted
•Self-assembled DNA nanostructure binds to bovine serum albumin and bovine liver catalase though non-covalent interactions.•Conformational and thermal stability of BSA and BLC is confirmed in presence of branched DNA nanostructures.•Enthalpy-driven exothermic reaction for BLC-bDNA complex supports the protective role of bDNA towards enzymatic activity of BLC.
The presence of a Higgsino-like neutralino next-to-lightest sparticle (NLSP) and a keV scale gravitino (G) LSP opens up new decay modes of the NLSP, mainly to a Higgs/Z boson and the LSP. Besides, a ...keV-scale gravitino as a warm dark matter candidate salvages a relatively light Higgsino-like NLSP from dark matter constraints. We focus on the prospects of observing at least one b jet and two opposite sign leptons with a large missing transverse momenta ( ≥ 1 b+ ℓ+ℓ− + ET) signal at the LHC. A distinguishing feature of this scenario is the production of longitudinal Z bosons in neutralino decays, unlike in the case of gauginolike neutralinos, where the Z is mostly transverse. The polarization information of the parent Z boson gets reflected in the angular distributions of the decay leptons and in some other variables derived therefrom.
PDF
