In recent years, several studies have reported on the relationship between diabetes and carpal tunnel syndrome (CTS). However, due to their contradictory results, a systematic review and ...meta-analysis were conducted to investigate this subject.
This study is a systematic review and meta-analysis of studies published in ISI Web of Science, Scopus, PubMed, Cochrane, Google Scholar, and Embase databases. Heterogeneity in the studies included in the meta-analysis was evaluated using statistical tests such as the Chi-square test, I2, and forest plots. Publication bias was assessed using Begg's and Egger's tests.
This investigation analyzed data from 42 studies conducted between 1985 and 2022, with a total of 3,377,816 participants. The meta-analysis demonstrated that the odds ratio (OR) of CTS in participants with a history of diabetes compared to those without was 1.90 (95% CI: 1.64-2.21; P-value < 0.001). Given that publication bias was observed in this study (Begg's test P-value = 0.01), the modified OR was calculated with consideration of missed studies, which was 1.68 (95% CI: 1.45-1.94; P-value < 0.001).
The results of this study suggest that diabetic patients have 90% higher odds of developing CTS compared to non-diabetic individuals, which is statistically significant.
A suite of 20 cuboid fibrous diamonds from the Democratic Republic of Congo was studied to determine mineral phases crystallized from diamond-forming fluids that were trapped as inclusions in ...diamonds. We identified minerals and non-crystalline components using their compositional trends in the electron microprobe analyses of inclusions, an innovative bulk X-ray diffraction analysis and characteristic FTIR and Raman peaks. The DRC diamonds contain fluid inclusions of the Ca–carbonatitic–silicic composition. Most common phases precipitated from the fluid are found to be high-Si micas (90–30% of the solids volume), complex non-crystalline Na–Ca–Mg–Fe carbonate matter and apatite (together 5–70%), leaving a residual aqueous solution of K, Cl and carbonate ions and gaseous CO
2. A notable absence of carbonate minerals in bulk X-ray diffraction patterns combined with the vibrational spectroscopy observations on the C–O bonds indicates that C may be included in dissolved or amorphous carbonate matter. The modes of the most abundant phases are controlled by chemical trends of the bulk fluid compositions. Other relatively rare ∼
30 minerals, including various minerals with structural and coordinated H
2O, are detected by the vibrational spectroscopic and X-ray analyses. The fluid also contains some hydrocarbons associated with the carbonate material. The presence of some rare minerals and exotic compositions of solid-solution minerals in the fluid suggest crystallization from a closed system with high salinity–high aH
2O–high aCO
2 composition that persisted to relatively low temperatures and pressures. The bulk of the fluid crystallized in the diamond stability field (
P
<
7
GPa,
T
<
950
°C), but continued to form hydrocarbons, accessory and deuteric phases down to 200
°C and 0.2
GPa. Overall, the mineralogy of the fluid resembles carbonatite.
Main radiation pathways in the landscape of Armenia Arakelyan, V. B.; Khachatryan, G. E.; Nalbandyan-Schwarz, A. G. ...
International journal of radiation biology,
08/2023, Volume:
99, Issue:
8
Journal Article
Peer reviewed
To investigate sources, accumulation, and vertical migration of radionuclides in Armenia, and their impact on biota.
This review describes the radiation status in the landscape of Armenia and ...features of the impact of natural and human-generated radiation on human and non-human biotas, according to studies of Armenian scientists carried out since the middle of the last century. The mountain landscape demonstrates the diversity, speciation, and radioresistance of the biota, which arise under radiation exposure in a variable environment. Although the effects of radiation have been described for a long time, some of them require further study. It is important to present the data collected in order to produce a base line for future studies of radiation effects and interactions with other stressors caused by climate change.
Distal occlusion is one of the most common dentoalveolar anomalies and can be the reason for the obstructive sleep apnea (OSA) syndrome development among children. The aim of the study was to ...investigate the relationship between cephalometric and OSA parameters in the pediatric population. Methods: The cohort study included 39 children with OSA symptoms. Orthodontic examination consisted of a cephalometric analysis of 39 linear and angular variables. Patients underwent a sleep diagnostic study. Statistical analysis was performed using SPSS 19.0.0. Results: Of the general sample, 53.8% were mouth breathers and 46.2% had a mixed type of breathing. Moreover, 30.8% of patients had bruxism. The mean apnea-hypopnea index and oxygen desaturation index were 4.6/h and 3.9/h, respectively. A 1.06 times increase in the SNA index indicated the anterior position of the upper jaw. The MnPLSN° exceeded the norm by 1.3 times, which indicated the posterior position of the lower jaw and vertical type of the growth. An increase in ANSPNSSPT° by 1.1 times indicated an inclination of the upper jaw in the posterior position and a narrowing of the nasal passages. Patients with pediatric OSA had a significantly smaller lower airway space and MPH parameter. Conclusion: Systematic orthodontic monitoring of children with pediatric OSA is important for diagnosis and timely treatment.
Many studies have proven that promotion focus corresponds to the logic of individualistic culture, while prevention focus is characteristic of collectivistic culture. Armenia, as a post-Soviet ...country, has not been included in cross-cultural studies, since it is not viewed as a typically collectivistic or individualistic society.
To investigate how promotion and prevention regulatory foci can predict subjective well-being, as conditioned by individualistic-collectivistic cultural orientations within Armenian society, and to reveal the links between regulatory focus and subjective well-being within Armenian culture, considering the effect of personality-culture fit.
We carried out two studies. In Study 1, regression analysis was conducted to reveal how promotion and prevention foci predicted different aspects of subjective well-being. In Study 2, mediation analysis was conducted to reveal how vertical and horizontal collectivism and individualism mediate the linkage between a promotion or prevention focus, and different aspects of subjective well-being.
Regression analysis replicated the findings of other studies, showing that promotion focus has a great predictive role in subjective well-being, while prevention focus neither predicts or obviates different aspects of subjective well-being. Mediation analysis indicated that vertical collectivism had a partially mediating effect on the linkage between promotion and cognitive, emotional, and psychological aspects of subjective well-being. Vertical individualism had a mediating effect on the linkage between prevention and social well-being.
Vertical collectivism is a consistent pattern in people experiencing subjective well-being when they behave in a promotion-based way in different settings in the Armenian cultural context.
Under conditions of make to order manufacturing in the micrologistic system of the enterprise, problems arise due to inefficient use of production capacities due to irrational use of productive labor ...resources. In order to solve the problem of material flow parameters of logistical optimization by increasing production «flexibility» in the production chain, we propose an algorithm of operational control through redistribution of industrial labor resources of an industrial enterprise. Practical application of this algorithm allows increasing flexibility of the enterprise to meet the market demand for products on individual orders, and to increase the efficiency of its activities.
Non‐alcoholic fatty liver disease (NAFLD) is frequently linked to metabolic disorders and is prevalent in obese and diabetic patients. The pathophysiology of NAFLD involves multiple factors, ...including insulin resistance (IR), oxidative stress (OS), inflammation, and genetic predisposition. Recently, there has been an emphasis on the use of herbal remedies with many people around the world resorting to phytonutrients or nutraceuticals for treatment of numerous health challenges in various national healthcare settings. Pomegranate (Punica granatum) parts, such as juice, peel, seed and flower, have high polyphenol content and is well known for its antioxidant capabilities. Pomegranate polyphenols, such as hydrolyzable tannins, anthocyanins, and flavonoids, have high antioxidant capabilities that can help lower the OS and inflammation associated with NAFLD. The study aimed to investigate whether pomegranate parts could attenuate OS, inflammation, and other risk factors associated with NAFLD, and ultimately prevent the development of the disease. The findings of this study revealed that: 1. pomegranate juice contains hypoglycemic qualities that can assist manage blood sugar levels, which is vital for avoiding and treating NAFLD. 2. Polyphenols from pomegranate flowers increase paraoxonase 1 (PON1) mRNA and protein levels in the liver, which can help protect liver enzymes and prevent NAFLD. 3. Punicalagin (PU) is one of the major ellagitannins found in pomegranate, and PU‐enriched pomegranate extract (PE) has been shown to inhibit HFD‐induced hyperlipidemia and hepatic lipid deposition in rats. 4. Pomegranate fruit consumption, which is high in antioxidants, can decrease the activity of AST and ALT (markers of liver damage), lower TNF‐α (a marker of inflammation), and improve overall antioxidant capacity in NAFLD patients. Overall, the polyphenols in pomegranate extracts have antioxidant, anti‐inflammatory, hypoglycemic, and protective effects on liver enzymes, which can help prevent and manage NAFLD effects on liver enzymes, which can help prevent and manage NAFLD.
Non‐alcoholic fatty liver disease (NAFLD) is a common chronic liver disease characterized by fat accumulation in the liver. Pomegranate has been shown to have beneficial effects on insulin resistance and obesity, which are linked to NAFLD pathogenesis. A study investigated the potential protective effect of pomegranate peel extract (PPE) against oxidative stress in the liver of rats with NAFLD. The results showed that PPE improved liver enzymes, inhibited lipogenesis, and enhanced the cellular redox status in the liver tissue of rats with NAFLD.
We consider the observational aspects of the value of dark energy density from quantum vacuum fluctuations based initially on the Gurzadyan–Xue model. We reduce the Djorgovski–Gurzadyan integral ...equation to a differential equation for the co-moving horizon and then, by means of the obtained explicit form for the luminosity distance, we construct the Hubble diagram for two classes of observational samples. For supernova and gamma-ray burst data we show that this approach provides viable predictions for distances up to
z
≃ 9, quantitatively at least as good as those provided by the Λ cold dark matter model. The Hubble parameter dependence
H
(
z
) of the two models also reveals mutual crossing at
z
= 0.4018, the interpretation of which is less evident.
•In total, 1123 neurologists from 27 countries participated.•Many respondents reported to discuss SUDEP only rarely.•The propensity to tell all patients was higher among those with epilepsy ...fellowship.
To investigate the opinions and attitudes of neurologists on the counseling about sudden unexpected death in epilepsy (SUDEP) worldwide.
Practicing neurologists from around the world were invited to participate in an online survey. On February 18th, 2021, we emailed an invitation including a questionnaire (using Google-forms) to the lead neurologists from 50 countries. The survey anonymously collected the demographic data of the participants and answers to the questions about their opinions and attitudes toward counseling about SUDEP.
In total, 1123 neurologists from 27 countries participated; 41.5% of the respondents reported they discuss the risk of SUDEP with patients and their care-givers only rarely. Specific subgroups of patients who should especially be told about this condition were considered to be those with poor antiseizure medication (ASM) adherence, frequent tonic-clonic seizures, or with drug-resistant epilepsy. The propensity to tell all patients with epilepsy (PWE) about SUDEP was higher among those with epilepsy fellowship. Having an epilepsy fellowship and working in an academic setting were factors associated with a comfortable discussion about SUDEP. There were significant differences between the world regions.
Neurologists often do not discuss SUDEP with patients and their care-givers. While the results of this study may not be representative of practitioners in each country, it seems that there is a severe dissociation between the clinical significance of SUDEP and the amount of attention that is devoted to this matter in daily practice by many neurologists around the world.
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