We report on the results of nuclear magnetic and quadrupole resonances of Cu in Cu2Fe2Ge4O13 consisting of weakly coupled Cu dimers and Fe chains. In the antiferromagnetic state below 39 K, we ...observed nuclear resonance of Cu under the internal magnetic field at the Cu site. An analysis of the internal field based on the square-planar coordination of Cu2+suggests that the 3d hole is mainly in the dx2−y2 orbital. In Cu2Sc2Ge4O13 including only Cu dimers, we observed oscillation of Cu spin-echo intensity as a function of the separation time between π/2 and π pulses. This is caused by indirect nuclear spin coupling mediated by strong intradimer exchange coupling of the electronic spins, indicating that the dimers are magnetically well isolated in these materials.
To evaluate the significance of achieving deep remission by induction therapy in lupus nephritis (LN) patients.
We assessed consecutive patients undergoing induction therapy for active LN. ...Achievement of complete renal response (CR) was defined as a urine protein creatinine ratio (UPCR) ≤0.5 g/gCr, and deep remission (DR) was defined as a UPCR ≤0.15 g/gCr with stabilisation of serum creatinine levels assessed every 2-3 months. We compared renal flare and damage accrual rates among patients with CR, CR without DR, and DR at 3, 6, and 12 months and later.
Fifty-nine Asian patients were enrolled, and the median observation period was 48.6 months. Of these, 55 patients achieved CR, and 33 achieved DR within 12 months of receiving induction therapy. The patients with DR within 12 months experienced a significantly lower rate of subsequent renal flare (p<0.001) and damage accrual (p=0.046) than those without CR, those with DR after 12 months, and those with no DR but CR within 12 months. In addition, younger age, shorter disease duration, lower urine protein at baseline, and earlier renal response were associated with DR within 12 months.
Achievement of DR within 12 months after induction therapy should be a treatment target for active LN, as it has implications for preventing renal flare and damage accrual.
A double phase (liquid/gas) xenon prototype detector of a 0.3 l active volume for WIMPs direct search has been constructed and tested. Proportional scintillation signals are observed by a multi-wire ...anode mounted in gas phase after ionization electrons drifted successfully long distance in liquid xenon. Both direct and proportional scintillation were used to discriminate electron recoil from nuclear recoil. Basic performances of the detector and the rejection efficiency of background gamma rays were demonstrated.
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