Abstract Purpose To examine the relationship between children's and adolescents' experiences with cyberbullying and traditional bullying and psychological health, physical health, and academic ...performance. Methods Nine hundred thirty-one students in grades 6 through 12 completed an anonymous survey examining their experiences with cyberbullying and traditional bullying. Also included were measures of anxiety, depression, self-esteem, physical well-being, school attendance, and academic performance. Results Participants were categorized as belonging to one of four groups: cyber victims, cyberbullies, cyber bully/victims, and those not involved in cyberbullying. A similar categorization was done with traditional bullying. Those in the bully/victim groups (and particularly the cyber bully/victim group) had the most negative scores on most measures of psychological health, physical, health, and academic performance. Conclusions There appears to be a substantial, although not perfect, overlap between involvement in traditional bullying and cyberbullying. Additionally, the physical, psychological, and academic correlates of the two types of bullying resembled one another.
The study presents the comparison of detection and recognition of concealed objects covered with various types of clothing by using passive imagers operating in a terahertz (THz) range at 1.2 mm ...(250 GHz) and a mid-wavelength infrared (MWIR) at 3–6 μm (50–100 THz). During this study, large dataset of images presenting various items covered with various types of clothing has been collected. The detection and classification algorithms aimed to operate robustly at high processing speed across these two spectrums. Properties of both spectrums, theoretical limitations, performance of imagers and physical properties of fabrics in both spectral domains are described. The paper presents a comparison of two deep learning–based processing methods. The comparison of the original results of various experiments for the two spectrums is presented.
The current study examined the role of the components of the Protection Motivation Theory of Health (PMT) in predicting protective health behaviors related to the COVID-19 virus. Through a snowball ...sampling procedure, in Wave 1 424 respondents completed a survey in March 2020. One hundred thirteen of these participants completed the same survey in Wave 2 in May 2020. Consistent with research on SARS, females and older individuals engaged in the behaviors more often than men and younger individuals. After accounting for these variables in predicting frequency of protective health behaviors, components of the PMT accounted for an additional 12% of the variance in Wave 1 and 16% in Wave 2, with perceived severity and outcome efficaciousness correlating positively with frequency. Anticipatory regret mediated the relationship between PMT and protective health behavior frequency. The results suggest that public health announcements that are tailored toward the severity of the virus and the efficacy of the health behaviors in decreasing the spread of the virus may meet with more success than those that heighten people's vulnerability to the disease.
Although the Internet has transformed the way our world operates, it has also served as a venue for cyberbullying, a serious form of misbehavior among youth. With many of today's youth experiencing ...acts of cyberbullying, a growing body of literature has begun to document the prevalence, predictors, and outcomes of this behavior, but the literature is highly fragmented and lacks theoretical focus. Therefore, our purpose in the present article is to provide a critical review of the existing cyberbullying research. The general aggression model is proposed as a useful theoretical framework from which to understand this phenomenon. Additionally, results from a meta-analytic review are presented to highlight the size of the relationships between cyberbullying and traditional bullying, as well as relationships between cyberbullying and other meaningful behavioral and psychological variables. Mixed effects meta-analysis results indicate that among the strongest associations with cyberbullying perpetration were normative beliefs about aggression and moral disengagement, and the strongest associations with cyberbullying victimization were stress and suicidal ideation. Several methodological and sample characteristics served as moderators of these relationships. Limitations of the meta-analysis include issues dealing with causality or directionality of these associations as well as generalizability for those meta-analytic estimates that are based on smaller sets of studies (k < 5). Finally, the present results uncover important areas for future research. We provide a relevant agenda, including the need for understanding the incremental impact of cyberbullying (over and above traditional bullying) on key behavioral and psychological outcomes.
Standard first-line therapy for metastatic, squamous non-small-cell lung cancer (NSCLC) is platinum-based chemotherapy or pembrolizumab (for patients with programmed death ligand 1 PD-L1 expression ...on ≥50% of tumor cells). More recently, pembrolizumab plus chemotherapy was shown to significantly prolong overall survival among patients with nonsquamous NSCLC.
In this double-blind, phase 3 trial, we randomly assigned, in a 1:1 ratio, 559 patients with untreated metastatic, squamous NSCLC to receive 200 mg of pembrolizumab or saline placebo for up to 35 cycles; all the patients also received carboplatin and either paclitaxel or nanoparticle albumin-bound nab-paclitaxel for the first 4 cycles. Primary end points were overall survival and progression-free survival.
After a median follow-up of 7.8 months, the median overall survival was 15.9 months (95% confidence interval CI, 13.2 to not reached) in the pembrolizumab-combination group and 11.3 months (95% CI, 9.5 to 14.8) in the placebo-combination group (hazard ratio for death, 0.64; 95% CI, 0.49 to 0.85; P<0.001). The overall survival benefit was consistent regardless of the level of PD-L1 expression. The median progression-free survival was 6.4 months (95% CI, 6.2 to 8.3) in the pembrolizumab-combination group and 4.8 months (95% CI, 4.3 to 5.7) in the placebo-combination group (hazard ratio for disease progression or death, 0.56; 95% CI, 0.45 to 0.70; P<0.001). Adverse events of grade 3 or higher occurred in 69.8% of the patients in the pembrolizumab-combination group and in 68.2% of the patients in the placebo-combination group. Discontinuation of treatment because of adverse events was more frequent in the pembrolizumab-combination group than in the placebo-combination group (13.3% vs. 6.4%).
In patients with previously untreated metastatic, squamous NSCLC, the addition of pembrolizumab to chemotherapy with carboplatin plus paclitaxel or nab-paclitaxel resulted in significantly longer overall survival and progression-free survival than chemotherapy alone. (Funded by Merck Sharp & Dohme; KEYNOTE-407 ClinicalTrials.gov number, NCT02775435 .).
Abstract Purpose Electronic communications technologies are affording children and adolescents new means of bullying one another. Referred to as electronic bullying, cyberbullying, or online social ...cruelty, this phenomenon includes bullying through e-mail, instant messaging, in a chat room, on a website, or through digital messages or images sent to a cell phone. The present study examined the prevalence of electronic bullying among middle school students. Methods A total of 3,767 middle school students in grades 6, 7, and 8 who attend six elementary and middle schools in the southeastern and northwestern United States completed a questionnaire, consisting of the Olweus Bully/Victim Questionnaire and 23 questions developed for this study that examined participants’ experiences with electronic bullying, as both victims and perpetrators. Results Of the students, 11% that they had been electronically bullied at least once in the last couple of months (victims only); 7% indicated that they were bully/victims; and 4% had electronically bullied someone else at least once in the previous couple of months (bullies only). The most common methods for electronic bullying (as reported by both victims and perpetrators) involved the use of instant messaging, chat rooms, and e-mail. Importantly, close to half of the electronic bully victims reported not knowing the perpetrator’s identity. Conclusions Electronic bullying represents a problem of significant magnitude. As children’s use of electronic communications technologies is unlikely to wane in coming years, continued attention to electronic bullying is critical. Implications of these findings for youth, parents, and educators are discussed.
The incidence of insulin resistance and type 2 diabetes (T2D) is increasing at alarming rates. In the quest to understand the underlying causes of and to identify novel therapeutic targets to treat ...T2D, scientists have become increasingly reliant on the use of rodent models. Here, we provide a discussion on the regulation of rodent glucose metabolism, highlighting key differences and similarities that exist between rodents and humans. In addition, some of the issues and considerations associated with assessing glucose homeostasis and insulin action are outlined. We also discuss the role of the liver vs. skeletal muscle in regulating whole body glucose metabolism in rodents, emphasizing the importance of defective hepatic glucose metabolism in the development of impaired glucose tolerance, insulin resistance, and T2D.
We investigate the importance of the far red wing of the Lya line of hydrogen in the atmospheres of cool white dwarfs of pure hydrogen composition. We find that this absorption process dominates all ...important sources of opacity in the blue part of the optical spectrum of these stars. Our successful fits to the spectra of cool DA/DC white dwarfs indicate that the far red wing of the Lya line is the source of opacity that had been missing in the models. The observed sequence of cool white dwarfs in color-color diagrams is very well reproduced by our new pure hydrogen atmosphere models, suggesting that the atmospheric composition of the coolest DC white dwarfs must be revisited.
Two studies generated profiles of cyberbullying/cyberincivility and traditional bullying/incivility in adults, particularly within the workplace. In Study 1, 20% of 3,699 participants had the ...majority of cyberbullying victimization and 7.5% had the majority of traditional bullying victimization occur in adulthood, with 30% saying they were bullied at work. Relationships between bullying and negative outcomes were found. Because of the clear evidence of bullying and cyberbullying in the workplace in Study 1, Study 2 addressed the relationship of these constructs to workplace incivility. Workplace face-to-face incivility and bullying were related among 321 participants, as were workplace cyberbullying and cyberincivility. Face-to-face incivility was more common than online incivility, face-to-face bullying, or online bullying, yet all four behaviors were associated with negative outcomes. Differences in intentionality, acceptability, and severity were observed, with workplace face-to-face bullying perceived as the most severe and having the greatest intentionality to harm. These results emphasize the importance of studying bullying among adults, and highlight the conceptual independence of bullying and incivility. Correlates of workplace aggression are discussed using job demands-resources theory.
Abstract
Neutrino events from IceCube have recently been associated with multiple astrophysical sources. Interestingly, these likely detections represent three distinct astrophysical source types: ...active galactic nuclei (AGNs), blazars, and tidal disruption events (TDEs). Here, we compute the expected contributions of AGNs, blazars, and TDEs to the overall cosmic neutrino flux detected by IceCube based on the associated events, IceCube’s sensitivity, and the source types’ astrophysical properties. We find that, despite being the most commonly identified sources, blazars cannot contribute more than 11% of the total flux (90% credible level), consistent with existing limits from stacked searches. On the other hand, we find that either AGNs or TDEs could contribute more than 50% of the total flux (90% credible level), although stacked searches further limit the TDE contribution to ≲30%. We also find that so-far unknown source types contribute at least 10% of the total cosmic flux with a probability of 80%. We assemble a pie chart that shows the most likely fractional contribution of each source type to IceCube’s total neutrino flux.
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