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  • Kaempferol induces programm... Kaempferol induces programmed cell death in Naegleria fowleri
    Lê, Hương Giang; Kang, Jung-Mi; Võ, Tuấn Cường Phytomedicine (Stuttgart), 10/2023, Volume: 119
    Journal Article
    Peer reviewed

    BACKGROUNDNaegleria fowleri is a brain-eating amoeba causing a fatal brain infection called primary amoebic meningoencephalitis (PAM). Despite its high mortality over 95%, effective therapeutic drug ...
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  • Prevalence of glucose-6-pho... Prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency among malaria patients in Upper Myanmar
    Lee, Jinyoung; Kim, Tae Im; Kang, Jung-Mi ... BMC infectious diseases, 03/2018, Volume: 18, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Glucose-6-phosphate dehydrogenase (G6PD; EC 1.1.1.49) deficiency is one of the most common X-linked recessive hereditary disorders in the world. Primaquine (PQ) has been used for radical cure of P. ...
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  • Genetic polymorphism of mer... Genetic polymorphism of merozoite surface protein-3 in Myanmar Plasmodium falciparum field isolates
    Lê, Hương Giang; Thái, Thị Lam; Kang, Jung-Mi ... Malaria journal, 05/2020, Volume: 19, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Plasmodium falciparum merozoite surface protein-3 (PfMSP-3) is a target of naturally acquired immunity against P. falciparum infection and is a promising vaccine candidate because of its critical ...
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  • Changing pattern of the gen... Changing pattern of the genetic diversities of Plasmodium falciparum merozoite surface protein-1 and merozoite surface protein-2 in Myanmar isolates
    Lê, Hương Giang; Kang, Jung-Mi; Jun, Hojong ... Malaria journal, 07/2019, Volume: 18, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Plasmodium falciparum merozoite surface protein-1 (PfMSP-1) and -2 (PfMSP-2) are major blood-stage vaccine candidate antigens. Understanding the genetic diversity of the genes, pfmsp-1 and pfmsp-2, ...
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  • Genetic diversity of Plasmo... Genetic diversity of Plasmodium vivax and Plasmodium falciparum lactate dehydrogenases in Myanmar isolates
    Lee, Jinyoung; Kim, Tae Im; Lê, Hương Giang ... Malaria journal, 02/2020, Volume: 19, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Plasmodium lactate dehydrogenase (pLDH) is a major target in diagnosing the erythrocytic stage of malaria parasites because it is highly expressed during blood-stage parasites and is distinguished ...
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  • Population genetic structur... Population genetic structure and natural selection of Plasmodium falciparum apical membrane antigen-1 in Myanmar isolates
    Kang, Jung-Mi; Lee, Jinyoung; Moe, Mya ... Malaria journal, 02/2018, Volume: 17, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Plasmodium falciparum apical membrane antigen-1 (PfAMA-1) is one of leading blood stage malaria vaccine candidates. However, genetic variation and antigenic diversity identified in global PfAMA-1 are ...
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  • Genetic polymorphism and na... Genetic polymorphism and natural selection of circumsporozoite protein in Myanmar Plasmodium vivax
    Võ, Tuấn Cường; Lê, Hương Giang; Kang, Jung-Mi ... Malaria journal, 09/2020, Volume: 19, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Circumsporozoite surface protein (CSP) of malaria parasites has been recognized as one of the leading vaccine candidates. Clinical trials of vaccines for vivax malaria incorporating Plasmodium vivax ...
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  • Fowlerstefin, a cysteine pr... Fowlerstefin, a cysteine protease inhibitor of Naegleria fowleri, induces inflammatory responses in BV-2 microglial cells in vitro
    Thái, Thị Lam; Kang, Jung-Mi; Lê, Hương Giang ... Parasites & vectors, 01/2020, Volume: 13, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Naegleria fowleri is a free-living amoeba that causes an opportunistic fatal infection known as primary amoebic meningoencephalitis (PAM) in humans. Cysteine proteases produced by the amoeba may play ...
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  • Genetic polymorphism and na... Genetic polymorphism and natural selection of circumsporozoite surface protein in Plasmodium falciparum field isolates from Myanmar
    Lê, Hương Giang; Kang, Jung-Mi; Moe, Mya ... Malaria journal, 10/2018, Volume: 17, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Plasmodium falciparum circumsporozoite protein (PfCSP) is one of the most extensively studied malaria vaccine candidates, but the genetic polymorphism of PfCSP within and among the global P. ...
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  • Spatio-temporal analysis of... Spatio-temporal analysis of genetic diversity of merozoite surface protein-3 alpha in Myanmar Plasmodium vivax isolates
    Võ, Tuấn Cường; Kang, Jung-Mi; Lê, Hương Giang ... Infection, genetics and evolution, 09/2024, Volume: 123
    Journal Article
    Peer reviewed
    Open access

    Myanmar aims to eliminate malaria by 2030. However, recent increase of malaria incidence is a great challenge to archive that goal. Increasing prevalence of Plasmodium vivax also hinders this ...
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