El papiloma escamoso del esófago (PEE) es una lesión benigna poco frecuente, asintomática y reconocida como un hallazgo incidental durante las endoscopias.
Es un estudio retrospectivo, donde se ...revisaron los reportes de endoscopias realizadas en el Servicio de Endoscopia del Hospital Central Sur de Alta Especialidad de PEMEX en un período de 10 años, recopilando los datos de los pacientes con PEE.
En el período de estudio se realizaron 9,884 endoscopias, teniendo 31 casos de PEE corroborado por patología, con una prevalencia del 0.37%. Edad media de 55.2 años. La concordancia de la imagen endoscópica con patología fue del 83.8%. La indicación más común del estudio fue el reflujo gastroesofágico, el hallazgo endoscópico más asociado la hernia hiatal y la localización más frecuente en el tercio medio del esófago.
El PEE es una patología poco frecuente, que en nuestro hospital tuvo una prevalencia similar a la reportada en la literatura. Los hallazgos endoscópicos e indicaciones de los estudios apoyan la teoría de la etiología relacionada con el reflujo gastroesofágico. Con altos grados de sospecha por endoscopia, observando que la concordancia con patología es alta.
The esophageal squamous papilloma (ESP) is a lesion that is uncommon and asymptomatic that is incidentally recognized during endoscopies.
A retrospective study was performed that included a review of endoscopy reports over a 10 year period from the Endoscopy Department of the Hospital Central Sur de Alta Especialidad de PEMEX, and the compiling of the information of the patients with ESP.
A total of 9,884 endoscopies were performed during the study period, with 31 pathology reports on esophageal squamous papilloma, with a prevalence of 0.37%. The mean age of the cases was 55.2 years. The concordance between endoscopic image and pathology reports was 83.8%. The most frequent indication for the endoscopy was gastro-esophageal reflux, with hiatal hernia being the frequent endoscopic finding, and the middle esophagus was the most common localization during endoscopy.
The ESP is an uncommon lesion, with a higher prevalence in our hospital than reported in the literature. The endoscopic findings and indications support the etiological theory of reflux. With highly levels of suspicion by endoscopy.
Simulacion virtual de brote epidemico en una unidad de dialisis Maldonado Lopez, Lili Ana; Perez Puerto, Maria Aurelia; Gonzalez-Aller, Francisco Javier Gallego ...
Revista de la Sociedad Española de Enfermería Nefrológica,
07/2009, Volume:
12, Issue:
3
Journal Article
El esófago de Barrett es una condición donde el epitelio esofágico es reemplazado por un epitelio columnar con células caliciformes. El riesgo de evolución hacia adenocarcinoma de esófago tiene una ...prevalencia del 0.5% anual. La cromoendoscopia virtual nos permite lograr un efecto similar a las tinciones, pero con solo apretar un botón, facilitando y dirigiendo específicamente la toma de biopsias.
Determinar la utilidad de la imagen de banda estrecha (NBI) en las endoscopias de pacientes con sospecha o diagnóstico de esófago de Barrett.
Es un estudio de evaluación diagnóstica de las biopsias tomadas con luz blanca comparado con las tomadas con NBI en donde se tenga sospecha o seguimiento del esófago de Barrett en el Servicio de Endoscopia del Hospital Central Sur de Alta Especialidad de PEMEX en el período de estudio.
En el período de estudio se realizaron 1,225 panendoscopias; se tomaron 127 biopsias por sospecha de esófago de Barrett (63 fueron hechas con luz blanca y 64 con NBI) y 124 por seguimiento del mismo (71 con luz blanca y 53 con NBI). Se observó que la sensibilidad y la especificidad para las endoscopias por primera vez con luz blanca fueron del 100% y del 84% respectivamente; y con NBI la sensibilidad fue del 100% y la especificidad del 93%. Para los estudios subsecuentes con luz blanca la sensibilidad fue del 92% y la especificidad del 92%; y con el uso de NBI la sensibilidad fue del 92% y la especificidad del 93%.
El uso de NBI en los estudios de endoscopia con sospecha de esófago de Barrett aumenta la especificidad.
Barrett esophagus is a condition that develops when the normal epithelium is replaced by a columnar epithelium with caliciform cells, with a prevalence of 5%. The risk of adenocarcinoma of the esophagus is 0.5% per year. Virtual chromoendoscopy gives similar results to using stains, but with only at the push of a button, specifically helps to direct the taking of biopsies.
Determine the usefulness of the narrow band imaging (NBI) in the endoscopies of patients with suspected or known Barrett esophagus.
An diagnosis evaluation study was performed on the biopsies taken with light compared with NBI of all the consecutive patients that had an endoscopy with the suspicion of or a known Barrett esophagus in the Endoscopy Service of the Hospital Central Sur de Alta Especialidad de PEMEX in the period of the study.
A total of 1,225 upper endoscopies were performed during the study period, with 127 biopsies taken due to the suspicion of Barrett esophagus (63 with white light and 64 with NBI). There were also 124 biopsies taken for follow-up of Barrett esophagus (71 with white light and 53 with NBI). The sensitivity and specificity of the white light endoscopies was 100% and 84%, respectively, and with NBI the sensitivity was 100% and specificity 93%. For the follow-up studies of Barrett esophagus with white light, the sensitivity and specificity were both 92%, and in the NBI follow-up studies the sensitivity was 92% and specificity 93%.
The use of NBI for studies of suspected Barrett esophagus increases the specificity and PPV compared with white light.
Simulación virtual de brote epidémico en una unidad de diálisis Jiménez Jaén, Purificación; Maldonado López, Lili Ana; Gras Baeza, María Ángeles ...
Revista de la Sociedad Española de Enfermería Nefrológica,
09/2009, Volume:
12, Issue:
3
Journal Article
Simulación virtual de brote epidémico en una unidad de diálisis Jiménez Jaén, Purificación; Maldonado López, Lili Ana; Gras Baeza, María Ángeles ...
Revista de la Sociedad Española de Enfermería Nefrológica,
09/2009, Volume:
12, Issue:
3
Journal Article
Xanthomonas axonopodis pv. manihotis (Xam) is the causal agent of bacterial blight of cassava, which is among the main components of human diet in Africa and South America. Current information about ...the molecular pathogenicity factors involved in the infection process of this organism is limited. Previous studies in other bacteria in this genus suggest that advanced draft genome sequences are valuable resources for molecular studies on their interaction with plants and could provide valuable tools for diagnostics and detection. Here we have generated the first manually annotated high-quality draft genome sequence of Xam strain CIO151. Its genomic structure is similar to that of other xanthomonads, especially Xanthomonas euvesicatoria and Xanthomonas citri pv. citri species. Several putative pathogenicity factors were identified, including type III effectors, cell wall-degrading enzymes and clusters encoding protein secretion systems. Specific characteristics in this genome include changes in the xanthomonadin cluster that could explain the lack of typical yellow color in all strains of this pathovar and the presence of 50 regions in the genome with atypical nucleotide composition. The genome sequence was used to predict and evaluate 22 variable number of tandem repeat (VNTR) loci that were subsequently demonstrated as polymorphic in representative Xam strains. Our results demonstrate that Xanthomonas axonopodis pv. manihotis strain CIO151 possesses ten clusters of pathogenicity factors conserved within the genus Xanthomonas. We report 126 genes that are potentially unique to Xam, as well as potential horizontal transfer events in the history of the genome. The relation of these regions with virulence and pathogenicity could explain several aspects of the biology of this pathogen, including its ability to colonize both vascular and non-vascular tissues of cassava plants. A set of 16 robust, polymorphic VNTR loci will be useful to develop a multi-locus VNTR analysis scheme for epidemiological surveillance of this disease.
Xanthomonas axonopodis pv. manihotis (Xam) is the causal agent of bacterial blight of cassava, which is among the main components of human diet in Africa and South America. Current information about ...the molecular pathogenicity factors involved in the infection process of this organism is limited. Previous studies in other bacteria in this genus suggest that advanced draft genome sequences are valuable resources for molecular studies on their interaction with plants and could provide valuable tools for diagnostics and detection. Here we have generated the first manually annotated high-quality draft genome sequence of Xam strain CIO151. Its genomic structure is similar to that of other xanthomonads, especially Xanthomonas euvesicatoria and Xanthomonas citri pv. citri species. Several putative pathogenicity factors were identified, including type III effectors, cell wall-degrading enzymes and clusters encoding protein secretion systems. Specific characteristics in this genome include changes in the xanthomonadin cluster that could explain the lack of typical yellow color in all strains of this pathovar and the presence of 50 regions in the genome with atypical nucleotide composition. The genome sequence was used to predict and evaluate 22 variable number of tandem repeat (VNTR) loci that were subsequently demonstrated as polymorphic in representative Xam strains. Our results demonstrate that Xanthomonas axonopodis pv. manihotis strain CIO151 possesses ten clusters of pathogenicity factors conserved within the genus Xanthomonas. We report 126 genes that are potentially unique to Xam, as well as potential horizontal transfer events in the history of the genome. The relation of these regions with virulence and pathogenicity could explain several aspects of the biology of this pathogen, including its ability to colonize both vascular and non-vascular tissues of cassava plants. A set of 16 robust, polymorphic VNTR loci will be useful to develop a multi-locus VNTR analysis scheme for epidemiological surveillance of this disease.
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