In prior work, fully inorganic perovskite nanocrystals of cesium lead halide (CsPbX3, X = Cl, Br, I), representing bright and tunable photoluminescence, have been synthesized using hot-inject ...approach and anion exchange reaction. Regrettably, the air instability and poor water resistant properties still hindered its application owing to their extremely fast reaction kinetics and easy anion exchange. Herein, we report a facile melting–quenching technique of CsPbX3 (X = Br, I) quantum dots (QDs) glass, and it also shows a tunable photoluminescence (520–698nm) controlled by the molar ratios of halide precursors. This melting–quenching CsPbX3 QDs glass exhibits high luminescent intensity, narrow photoluminescence (PL) emission, including the similar bandgap energies as CsPbX3 QDs solution. The chemical stability and tunable emission make perovskite QDs glass appealing for lighting display, particularly for warm lighting source, which realize the application of solid-state lighting for CsPbX3 QDs.
Perovskite materials have received extensive attention as optical gain media. However, it is tough to realize lasing using such materials on account of the unstable structure of MAPbI
3
/CsPbI
3
...nanocrystals (NCs), and the propensity for mixed-halogen perovskites to undergo phase decomposition into bromine-rich and iodide-rich regions under intense laser irradiation. To solve this issue, we fabricated CsPbX
3
(X = Br, I) NCs, which were embedded into a glassy matrix with high stability. In addition, by doping Br
−
ions into the CsPbI
3
NCs to partially replace I
−
ions, the optical efficiency and the optical gain properties were found to be significantly improved. Here, under 800 nm pulse laser excitation, red random lasing was realized with the assistance of such anion modulation. Moreover, we demonstrate that the perovskite NCs glasses (PNG) show strong water stability after immersion in water for one week, seeding a promise for application in high-definition (HD) displays and photonic devices.
•The quantum yield of the obtained ternary AgInS2 QDs was up to 62% with the emission peak of 642nm under the excitation of 460nm.•Colorful luminescent Ag–Zn–In–S QDs were obtained by adding Zn salts ...directly as well as Ag and In precursors.•The obtained highly luminescent quantum dots showed promising applications in the white light emitting diodes (W-LED).•The electroluminescence (EL) of AgInS2 QDs was observed in QD-LED device.
Silver indium sulfide (AIS) quantum dots (QDs) with different Ag/In molar ratios were synthesized via a hot-injection method. Intense photoluminescence (PL) originating from the donor–acceptor pair recombination were observed for all the samples and the emission peak blue-shifted from 739 to 632nm, being similar to the behavior of the absorption onset as the Ag/In ratios decreased. The highest PL quantum yield (QY) of the obtained ternary AIS QDs was ca. 62% with an optimum ratio of Ag/In=1/4. Compared with AIS QDs, when Zn ions were introduced, the absorption spectra of the obtained quaternary Ag–Zn–In–S QDs were blue-shifted, and their emission peaks moved to higher energies accordingly, showing a tunable emission from red to green by altering the band gap energy. In order to further study the electroluminescence (EL) as well as looking forward to the applications in the optoelectronic devices of the obtained highly luminescent nanoparticles, the colloidal AIS QDs were deposited as thin films to the sandwich-like structured QD-LED. The experimental results showed that the obtained EL device exhibited EL emission originated from QDs thin films by adjusting the turn on voltage, which is for the first time to realize EL of AIS QDs in such QD-LED.
In this report, a mixed‐metal cation‐based halide perovskite (HP) CsPb1−xTixBr3 quantum dots (QDs) were first embedded in the B–Si–Zn glasses using a traditional approach of melt quenching and heat ...treating. A battery of test results such as photoluminescence, X‐ray diffraction, and time‐resolved attenuation prove that Ti ions do not destroy the properties of CsPbBr3, and they are successfully doped into CsPbBr3. At the same time, the doping of Ti ions also reduces the toxicity of lead. By altering the ratio of Pb/Ti, we determined the optimum ratio of CsPb0.7Ti0.3Br3 QDs through experimental data. Due to the excellent optical properties and stability of CsPb0.7Ti0.3Br3 QDs glass, it was designed to construct the white‐light emitting diode device with tunable color coordinate, color rendering index, correlated color temperature, and a high luminous efficiency compared with CsPbBr3 QDs glass, which may be a promising candidate for the field of lighting and displays.
Display omitted
Currently, the exploration of non-rare-earth Mn4+-activated oxide red phosphor is of great demand for phosphor-converted warm white-light-emitting diodes (W-LEDs). Here, Mg2TiO4:Mn4+ ...and Mg2TiO4:Mn4+,Zn2+ red phosphors were prepared using a solid-state reaction route and exhibited a strong red emission peaked at ∼657nm. The microstructure and luminescent performance of the obtained red phosphors were investigated. Additionally, the concentration quenching and nephelauxetic effect of Mn4+ in the Mg2TiO4 host lattice were evaluated in detail. Moreover, Mg2TiO4:Mn4+,Zn2+ manifests an enhanced luminescence intensity compared to the sample without Zn2+ doping with a quantum efficiency of 38.2% and good thermal resistance of ΔE=0.36eV. As proof of concept, when we incorporated Mg2TiO4:Mn4+,Zn2+ and commercial YAG:Ce3+ into the package of a blue LED chip, a warm white light was produced with a high colour rendering index and a low correlated colour temperature; thus, they have promise as an application as a colour converter in the field of warm W-LEDs.
The use of multiparametric magnetic resonance imaging (mpMRI) has become a common technique used in guiding biopsy and developing treatment plans for prostate lesions. While this technique is ...effective, non-invasive methods such as radiomics have gained popularity for extracting imaging features to develop predictive models for clinical tasks. The aim is to minimize invasive processes for improved management of prostate cancer (PCa). This study reviews recent research progress in MRI-based radiomics for PCa, including the radiomics pipeline and potential factors affecting personalized diagnosis. The integration of artificial intelligence (AI) with medical imaging is also discussed, in line with the development trend of radiogenomics and multi-omics. The survey highlights the need for more data from multiple institutions to avoid bias and generalize the predictive model. The AI-based radiomics model is considered a promising clinical tool with good prospects for application.
RNF20, an E3 ligase critical for monoubiquitination of histone H2B at lysine 120 (H2Bub), has been implicated in the regulation of various cellar processes; however, its physiological roles in ...adipocytes remain poorly characterized. Here, we report that the adipocyte-specific knockout of Rnf20 (ASKO) in mice led to progressive fat loss, organomegaly and hyperinsulinemia. Despite signs of hyperinsulinemia, normal insulin sensitivity and improved glucose tolerance were observed in the young and aged CD-fed ASKO mice. In addition, high-fat dietfed ASKO mice developed severe liver steatosis. Moreover, we observed that the ASKO mice were extremely sensitive to a cold environment due to decreased expression levels of brown adipose tissue (BAT) selective genes, including uncoupling protein 1 ( Ucp1), and impaired mitochondrial functions. Significantly decreased levels of peroxisome proliferator-activated receptor gamma ( Pparγ) were observed in the gonadal white adipose tissues (gWAT) from the ASKO mice, suggesting that Rnf20 regulates adipogenesis, at least in part, through Pparγ. Rosiglitazone-treated ASKO mice exhibited increased fat mass compared to that of the non-treated ASKO mice. Collectively, our results illustrate the critical role of RNF20 in control of white and brown adipose tissue development and physiological function.
Beige adipose tissue has been considered to have potential applications in combating obesity and its related metabolic diseases. However, the mechanisms of acute cold-stimulated beige formation still ...remain largely unknown. Here, transcriptional analysis of acute cold-stimulated (4 °C for 4 h) subcutaneous white adipose tissue (sWAT) was conducted to determine the molecular signatures that might be involved in beige formation. Histological analysis confirmed the appearance of beige adipocytes in acute cold-treated sWAT. The RNA-sequencing data revealed that 714 genes were differentially expressed (
-value < 0.05 and fold change > 2), in which 221 genes were upregulated and 493 genes were downregulated. Gene Ontology (GO) analyses showed that the upregulated genes were enriched in the GO terms related to lipid metabolic process, fatty acid metabolic process, lipid oxidation, fatty acid oxidation, etc. In contrast, downregulated genes were assigned the GO terms of regulation of immune response, regulation of response to stimulus, defense response, etc. The expressions of some browning candidate genes were validated in cold-treated sWAT and 3T3-L1 cell browning differentiation. In summary, our results illustrated the transcriptional response of sWAT to acute cold exposure and identified the genes, including
,
,
, and
, involved in beige adipocyte formation in mice.
Fat deposition, which influences pork production, meat quality and growth efficiency, is an economically important trait in pigs. Numerous studies have demonstrated that stearoyl-CoA desaturase ...(SCD), a key enzyme that catalyzes the conversion of saturated fatty acids into monounsaturated fatty acids, is associated with fatty acid composition in pigs. As
was observed to be significantly induced in 3T3-L1 preadipocytes differentiation, we hypothesized that it plays a role in porcine adipocyte differentiation and fat deposition. In this study, we revealed that
is highly expressed in adipose tissues from seven-day-old piglets, compared to its expression in tissues from four-month-old adult pigs. Moreover, we found that
and lipogenesis-related genes were induced significantly in differentiated porcine adipocytes. Using CRISPR/Cas9 technology, we generated
porcine embryonic fibroblasts (PEFs) and found that the loss of
led to dramatically decreased transdifferentiation efficiency, as evidenced by the decreased expression of known lipid synthesis-related genes, lower levels of oil red O staining and significantly lower levels of triglyceride content. Our study demonstrates the critical role of
expression in porcine adipocyte differentiation and paves the way for identifying it as the promising candidate gene for less fat deposition in pigs.
PDF
